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Psilocybin Produced in Yeast

phys.org

11–20 of 214 posts

Re: Psilocybin Produced in Yeast

#11
post #10
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Hey, drug on wars still exists in the world. You can get excessive jail time just for having some (regardless of quantity) marijuana on you - and that is in "western" country. It was not so long ago that "marijuana had no possible medical application" and was scheduled as a class A drug in UK (and I think, still is). There is a lot of stigma, and decades of bad science, propaganda, and manufactured hatred run deep. R…

Cannabis was downgraded from class A to a class C drug in the UK in 2004, but was upgraded to class B five years later.

https://en.wikipedia.org/wiki/Drugs_controlled_by_the_UK_Mis...

Re: Psilocybin Produced in Yeast

#12
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

It’s not hard or expensive to turn brown rice flour and vermiculite into mushrooms. The bit about expensive to create a pharmaceutical compound growing from a mushroom is just silly. Extraction can’t be that expensive.

Re: Psilocybin Produced in Yeast

#13
post #10

Earlier quoted context omitted.

Hey, drug on wars still exists in the world. You can get excessive jail time just for having some (regardless of quantity) marijuana on you - and that is in "western" country. It was not so long ago that "marijuana had no possible medical application" and was scheduled as a class A drug in UK (and I think, still is). There is a lot of stigma, and decades of bad science, propaganda, and manufactured hatred run deep. R…

Cannabis was downgraded from class A to a class C drug in the UK in 2004, but was upgraded to class B five years later. https://en.wikipedia.org/wiki/Drugs_controlled_by_the_UK_Mis...

[deleted]

Re: Psilocybin Produced in Yeast

#14
post #10
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Hey, drug on wars still exists in the world. You can get excessive jail time just for having some (regardless of quantity) marijuana on you - and that is in "western" country. It was not so long ago that "marijuana had no possible medical application" and was scheduled as a class A drug in UK (and I think, still is). There is a lot of stigma, and decades of bad science, propaganda, and manufactured hatred run deep. R…

You can go to jail for alcohol too. Just depends where you are.

Re: Psilocybin Produced in Yeast

#15
post #14
post #10

Earlier quoted context omitted.

Hey, drug on wars still exists in the world. You can get excessive jail time just for having some (regardless of quantity) marijuana on you - and that is in "western" country. It was not so long ago that "marijuana had no possible medical application" and was scheduled as a class A drug in UK (and I think, still is). There is a lot of stigma, and decades of bad science, propaganda, and manufactured hatred run deep. R…

You can go to jail for alcohol too. Just depends where you are.

[deleted]

Re: Psilocybin Produced in Yeast

#16
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

As far as I understand it's too inconsistent, i.e. very unevenly distributed within one fruiting body. Not sure if that's the reason, but: if you ever bought mushrooms/truffles in the Netherlands, there is no psylocibin content on the box. And if you try googling, the estimates vary pretty wildly (although it's possible that it's just a lack or proper research)

Also not everyone enjoys the taste of mushrooms or truffles. And psychedelic entities don't care whether they are coming from naturally occurring or synthesized psylocibin ;)

Also, humility and appreciation come in different shapes: for example I recall that Shulgin never consumed his pure psychedelics with juice because he could distinguish 'chemical' tastes and had appreciation for that

Re: Psilocybin Produced in Yeast

#17
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Someone more knowledgeable please step in to correct me but: I think what can be desirable from this process is the lack of variability in the product when you produce it at scale.

Re: Psilocybin Produced in Yeast

#18
post #12
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

It’s not hard or expensive to turn brown rice flour and vermiculite into mushrooms. The bit about expensive to create a pharmaceutical compound growing from a mushroom is just silly. Extraction can’t be that expensive.

> Extraction can’t be that expensive.

From the article, apparently yes it can: "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms"

Re: Psilocybin Produced in Yeast

#19
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

I do wonder what is lost, too. Some folks talk about "mushroom pills" (simply powdered, full spectrum mushrooms) and some talk about "psilocybin extract". It's my understanding that different psilocybe mushrooms species have different effects due to varying levels of not just psilocybin, but psilocin (psilocybin metabolizes to psilocin, but it is also in many species), baeocystin (mexicanas tend to be higher in this) and norbaeocystin.

Re: Psilocybin Produced in Yeast

#20
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

As far as I understand it's too inconsistent, i.e. very unevenly distributed within one fruiting body. Not sure if that's the reason, but: if you ever bought mushrooms/truffles in the Netherlands, there is no psylocibin content on the box. And if you try googling, the estimates vary pretty wildly (although it's possible that it's just a lack or proper research) Also not everyone enjoys the taste of mushrooms or truff…

With regards to the taste, grinding them up and mixing them into melted chocolate will negate all taste issues (or consistency, I find the getting bits stuck in your teeth is what really sucks).
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