Covid-19 at a homeless shelter in Boston: Implications for universal testing

Post by irishcoffee » Wed, Apr 15, 2020, 6:26 PM UTC

smallgovt wrote: post #17

jcp2fa wrote: post #6

> Cough (7.5%), shortness of breath (1.4%), and fever (0.7%) were all uncommon among COVID-positive individuals It seems the more important point here is that the majority of the COVID-positive individuals were asymptomatic, putting another datapoint towards the conclusion that there are orders of magnitude more people that have this disease than have tested positive. We need more studies to gather data on these asym…

> We need more studies to gather data on these asymptomatic cases if we want to reopen the economy soon. I don't understand what's so hard about measuring population infection rate. Assuming the population infection rate is between 1-10%, we would only need to do around ~500 randomized tests to achieve a 95% confidence interval of +/- 1%. For example, let's say we tested 500 random NYC residents for COVID and found t…

Post by irishcoffee » Wed, Apr 15, 2020, 6:29 PM UTC

gnulinux wrote: post #16

drtillberg wrote: post #12

Earlier quoted context omitted.

There are several variables here but it's also important to keep in mind that the 36% positive rate in this cohort presumably does not include people who had the virus and recovered.

A Diamond Princess ex-passenger died as late as March 24. The first patient was tested positive on February 1, and the ship was quarantined on Feb 4, and everyone left the ship on March 1. It doesn't seem unlikely you can die from this virus a month (or even two months?) after testing positive. Or maybe I'm missing something?

Post by downerending » Wed, Apr 15, 2020, 6:34 PM UTC

Post by Retric » Wed, Apr 15, 2020, 6:36 PM UTC

gnulinux wrote: post #26

Retric wrote: post #20

Earlier quoted context omitted.

No for several reasons. The Dimond Princess had over 100 crew of young healthy adults test positive and only 25% where asymptotic long term. Additionally South Korea has a massive effort into contact traction which demonstrated just how rapidly the disease spread. Their mortality numbers looked to be about 0.6% early on, but eventually hit 2% a month after the peak with people spending weeks in critical condition. On…

When we say long term here, do we mean within the 14 day incubation period that's been going around? Or does this imply incubation period is likely a lot more than 14 days, maybe in the order of months?

Post by autokad » Wed, Apr 15, 2020, 6:38 PM UTC

raphlinus wrote: post #18

gnulinux wrote: post #8

Earlier quoted context omitted.

It seems to indicate this disease infected a lot more than what we see, and maybe mortality rate is lower than what we currently assume. Maybe it's around 0.1% to 0.5%. So is it possible this disease appeared in China way before December, maybe a few months back. Then in December it reached a saturation point (i.e. infected hundreds of thousands of people, so deaths started to get noticed by respiratory specialists).…

No. We know from genomic analysis [1] that "The common ancestor of circulating viruses appears to have emerged in Wuhan, China, in late Nov or early Dec 2019." It's fun to speculate about other possibilities, but I personally like to stick to what the science tells us. [1]: https://twitter.com/nextstrain/status/1248707010750640128