Earlier quoted context omitted.
There is another point too, which also to some extend goes against your point—that we model epidemiology in standard ways, and that in order to use those standard ways we need the parameters in the set of differential equations. And these do make predictions based on the equilibria. I am not saying they solve everything, but they are routinely used to for example calculate how many people need to be vaccinated to sto…
The point of the parent is you can't actually find R_0 because R_0 depends on the behaviors of millions of people which cumulatively are based on billions of factors. R_0 isn't a constant, it's an equation. Mathematically, unless you get really lucky or have a very idealized system, the standard models underfit the actual system. The models can still be useful though, e.g. 'we must reduce r0 below r_critical to elimi…
Why it’s so hard to make a good Covid-19 model
81–90 of 96 posts
Re: Why it’s so hard to make a good Covid-19 model
#82Re: Why it’s so hard to make a good Covid-19 model
#83Earlier quoted context omitted.
you can predict human behavior with big data and linear models/embeddings with a few billion parameters. This works so unbelievably well, I expect that eventually health modelling folks will do this, provided they have enough high quality data.
Alice gives Bob a number, x, and tells Bob to calculate f(x), where f(x) is defined as the partial function with goedel index x applied to input x. She says that if or when Bob finishes, he should come bring her his answer and they'll get drinks together. Given parameter x, do Bob and Alice ever get drinks together?
Re: Why it’s so hard to make a good Covid-19 model
#84Earlier quoted context omitted.
Even without changing behavior, R0 can change as a virus enters different conditions. The flu in the winter (aka: Flu season) has higher R0 than the flu in the summer. Even if all humans acted the same in both cases. R0 is assumed to be a constant so that the math / models work. But it really changes dramatically in practice. Maybe someone else will eventually make a model where the constant is more... constant. But…
How certain of this are we (for the flu)? When I've looked into it, I've found it difficult to assess the degree to which we are looking at "behavior changes between seasons" vs "the season matters". Reasons the season might matter: Thicker air (higher humidity) may reduce particulate spread. Viral lifespan may be different under different temperatures. Yet, in researching the issue, I tend to find things like "well,…
They stuck a bunch of guinea pigs into a box, one box at 41F, a 2nd at 68F, and a third at 86F.
The box with 41F had the highest transmission rate. The box at 68F and 86F had lower transmission rates, even 0% transmission rate in the presence of 80% humidity.
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No such experiment exists for COVID19 yet. But because COVID19 continues to exponentially grow in the southern hemisphere (Australia in particular), there doesn't seem to be a relationship between temperature, humidity, and COVID19 like there is with the flu.
Re: Why it’s so hard to make a good Covid-19 model
#85Note that this article is from March 31st, and while that wouldn't normally be very long ago things are moving extremely quickly.
The main shift I've noticed (as a layman) is that people are thinking the illness is more contagious and less fatal than first thought. That explains the downward revisions in future deaths, but it also means that physical distancing is more effective and more important than first thought. Because a carrier that stays home is infecting ~5 less people rather than ~2 less people. The thing I'm worried about today is po…
The remainder should treat Corona as they do with the common flu, that is what the data is telling us.
References https://www.globalresearch.ca/swiss-doctor-covid-19/5707642
https://www.epicentro.iss.it/coronavirus/bollettino/Report-C... (Italian)
Re: Why it’s so hard to make a good Covid-19 model
#86What this article misses is that simple models of complex systems in science are most useful for understanding the dynamics of phenomena, not for making accurate quantitative predictions. This is not a model of a mass accelerating in a vacuum where Newton's laws are sufficient to a high degree of accuracy, or even a numerical model of the aerodynamics of an airplane, where the physics are well understood but there ar…
Well said, but it should be noted that making quantitative predictions based on simple models (and scattershot data) of complex systems is FiveThirtyEight's bailiwick and Nate Silver's claim to fame. The subtext of the article is that the problem is so difficult even they are stumped.
Re: Why it’s so hard to make a good Covid-19 model
#87Earlier quoted context omitted.
I don’t know that anyone expected (nearly) every state to impose a stay-at-home order. Crashing our economy into a brick wall is not an easy decision. I frankly expected things to get much worse before state governments took action. Obviously we could have done much better, much sooner, but I certainly can believe why early estimates were much more pessimistic. And that’s all disregarding the fact that we still don’t…
> I don’t know that anyone expected (nearly) every state to impose a stay-at-home order. IHME model did. And it still overestimated (and continues to overestimate) by a lot. What it predicted initially isn't even observed in countries where there's no lockdown at all.
Especially given all the modeling challenges, you cannot simply take the peak of the posterior as "the truth."
Re: Why it’s so hard to make a good Covid-19 model
#88Earlier quoted context omitted.
> I don’t know that anyone expected (nearly) every state to impose a stay-at-home order. IHME model did. And it still overestimated (and continues to overestimate) by a lot. What it predicted initially isn't even observed in countries where there's no lockdown at all.
The current IHME best estimates are well within the uncertainty regions of the earlier predictions. Especially given all the modeling challenges, you cannot simply take the peak of the posterior as "the truth."
Re: Why it’s so hard to make a good Covid-19 model
#89What this article misses is that simple models of complex systems in science are most useful for understanding the dynamics of phenomena, not for making accurate quantitative predictions. This is not a model of a mass accelerating in a vacuum where Newton's laws are sufficient to a high degree of accuracy, or even a numerical model of the aerodynamics of an airplane, where the physics are well understood but there ar…
Agree. I think a better exposition on COVID-19 models is Zenep Tufecki's article in The Atlantic [1]. TLDR: They're more directional roadmaps, showing you which possible outcome paths you need to prune off the tree of outcomes, not exact numerical predictions. [1] https://www.theatlantic.com/technology/archive/2020/04/coron...
Re: Why it’s so hard to make a good Covid-19 model
#90In jest, I am imagining a bunch of data scientists working late into the night, running the numbers and various scenarios, and then one person finally stands up and says, "F K it, let's just shut down the whole country and hope for the best."