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What's a virus, anyway? The bare-bones basics

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Re: What's a virus, anyway? The bare-bones basics

#151
post #105

Earlier quoted context omitted.

what’s the purpose of an amoeba? or a mosquito? or a duck? or a chimpanzee?

Would you not say they each have more purpose than a virus?

You're begging the question here; you need to establish they have any purpose before you can ask if one has more than the other.

Re: What's a virus, anyway? The bare-bones basics

#152
What always fascinates me is that biologists talk about how these large molecules bind and self-assemble, and how enzymes control the reactions and so forth, but what are the odds? It's almost like putting the parts in the mixer, and getting your little machine in the output. I have very hard time imagining it, especially in the cell which has thousands different molecules going on inside it, how everything gets in the proper place in the end.

Re: What's a virus, anyway? The bare-bones basics

#153
post #152

What always fascinates me is that biologists talk about how these large molecules bind and self-assemble, and how enzymes control the reactions and so forth, but what are the odds? It's almost like putting the parts in the mixer, and getting your little machine in the output. I have very hard time imagining it, especially in the cell which has thousands different molecules going on inside it, how everything gets in t…

You seem to be trying to get yourself into a certain rabbit hole, if that's the case let me assist you by introducing you to the Watchmaker analogy: https://en.m.wikipedia.org/wiki/Watchmaker_analogy

Re: What's a virus, anyway? The bare-bones basics

#154
post #152

What always fascinates me is that biologists talk about how these large molecules bind and self-assemble, and how enzymes control the reactions and so forth, but what are the odds? It's almost like putting the parts in the mixer, and getting your little machine in the output. I have very hard time imagining it, especially in the cell which has thousands different molecules going on inside it, how everything gets in t…

Firstly, evolution over billions of years makes it possible. But in more direct answer to your question about how these things self assemble - at this level atomic forces are like little magnets (I mean, literally they are the electromagnetic force) and those cause the atoms to arrange themselves in particular ways. There are lots of videos online showing this, eg. one I picked at random: https://www.youtube.com/watch?v=muNNSAYZDS8

Re: What's a virus, anyway? The bare-bones basics

#155
post #25

Is there a a good read on how RNA and DNA work for a Computer Scientist? And more generally how biology, genetics, epigenetics, virus, etc work? Many vulgarization sources say that DNA is like the source code of life. But they mostly skim across the issue and go to conclusions like "this gene or set of genes are responsible for that outcome". But coming from a CS background that sounds a bit like non-sense. I feel li…

Part I of Molecular Biology of the Cell is the best read in my opinion, regardless whether you have a CS background.

Can second this - a superb book that really helped me understand a little about what is going on.

Re: What's a virus, anyway? The bare-bones basics

#157
post #154
post #152

What always fascinates me is that biologists talk about how these large molecules bind and self-assemble, and how enzymes control the reactions and so forth, but what are the odds? It's almost like putting the parts in the mixer, and getting your little machine in the output. I have very hard time imagining it, especially in the cell which has thousands different molecules going on inside it, how everything gets in t…

Firstly, evolution over billions of years makes it possible. But in more direct answer to your question about how these things self assemble - at this level atomic forces are like little magnets (I mean, literally they are the electromagnetic force) and those cause the atoms to arrange themselves in particular ways. There are lots of videos online showing this, eg. one I picked at random: https://www.youtube.com/watc…

Exactly, molecular self-assembly is completely obvious once one can see the equivalent with his own eyes.

I hope nobody complains "but he shakes the flask" -- because that is exactly what the temperature is -- how fast the particles "jiggle" as Richard Feynman would that describe:

https://www.youtube.com/watch?v=K_y5iKcDdOQ

Re: What's a virus, anyway? The bare-bones basics

#158

Earlier quoted context omitted.

Is this based on basic research or demographic analysis? Has the research ruled out the possibility that people who are being treated for high blood pressure are more likely to be older and in poorer shape? Because that's a pretty strong confounding effect unless the research in question is a randomized controlled trial. I've also heard conflicting reports about Ibuprofen. I don't think anyone knows for sure.

My initial thought on Ibuprofen is just correlation not causation. How many people who get a fever will try Ibuprofen to try to lower the fever? Probably quite a few. When these people die its easy to say "well they all had Ibuprofen". That doesn't mean it had any effect. On the flip side, NSAIDs do reduce inflammation and inflammation is part of the body's response to various stressors; I could see that lowering our…

Speculation surrounds ACE inhibitors (ACEI), which are a type of high blood pressure medication, in that they may dampen your immune response to viruses over long time usage. The other speculation is that circulating amounts of ACE2 are increased by ACEI and SARS-Cov-2 specifically binds to ACE2. The confounding aspects are as you suggest that the overall health including kidney health are often poorer in people with hypertension.

Re: What's a virus, anyway? The bare-bones basics

#160
post #64

Earlier quoted context omitted.

The cliff notes version of it is that DNA encodes the information on how to build proteins. https://en.wikipedia.org/wiki/Central_dogma_of_molecular_bio... Proteins are built out of a chain of aminoacids. There are 20 different kinds of aminoacid, and the particular sequence of aminoacids determines the shape of the protein, and therefore its biological function. https://en.wikipedia.org/wiki/Amino_acid To build a pr…

Why do cells replicate virus rns so much, why don't we replicate out own rna out of control by the same mechanism?

Humans have developed protections against some rogue RNA, since out of control fork bombs randomly happening isn't a thing that makes you successful at reproduction.

The Virus reproduces using a fork bomb but for us it's deadly.

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