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Lyme disease bacteria eradicated by new drug in early tests

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Re: Lyme disease bacteria eradicated by new drug in early tests

#61
post #33

Note that they're carefully dancing around the elephant in the room: As far as I know, no one has ever demonstrated that Lyme spirochetes survive a course of standard antibiotics (Emphasis mine): > Standard treatment of Lyme disease is oral antibiotics, typically doxycycline, in the early stages of the disease; but for reasons that are unclear, the antibiotics don't work for up to 20% of people with the tick-borne il…

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

Lyme has three known forms of existence in mammals:

1) spirochete reproductive form and susceptible to a number of antibiotics (vitro/vivo) 2) round body "starvation forms" which are resistant to most antibiotics (vitro/vivo) 3) biofilm colonies which harbor many pathogens, metals and mycotoxins are resistant to antibiotics (think immunosuppression here)

I've gone through a shit ton of tests in the last few years going over much of this. I have relatives that experienced it as well. There is growing scientific evidence a ton of clinical improvement, yet "anecdotal" patient evidence that many of these pathogens can persist beyond initial treatment. Buhner does an excellent job of explaining some of this in "Healing Lyme" and backs it up with studies from around the world. His protocols certainly help people (myself included).

Immune expression and context is a tough nut to crack and we need billions of more data points capturing cytokine signaling in conjunction with T-cell, Nk cells, mast cells, antibodies, etc to get a better understanding of HOW UNIQUE EACH IMMUNE RESPONSE IS TO A PATHOGEN. Life on our planet is biological and tightly coupled with bacterial/parasitic/viral pathogens and would not exist without them. Things quickly change through reproduction or in the case of Borellia by shifting its outer protein to better evade compromised immune systems. Or has there just been one flu/corona/etc viral strain in the last hundred years? (Mind the 'gap' with disulfiram. It seems side effects vary, but also the quick elimination of Lyme, Babesia (not sure about Bartonella, which is mainly endothelial), and the cytokines cascades they trigger, but removing them all it once vs reducing them from severe to immune manageable levels might cause its own set of issues.

I won't bring up the CDC as they've failed millions of Lymies at this point with poor test protocols and failure to push for more research data. Test skipping 31, 34 antibody proteins when they are primary Borellia proteins (if the body is able to produce them, immunocomprimised or the load from multiple infections). The single dose doxy is absolute bullshit (1 data point from me). The denial that ticks can transmit Borellia (Lyme) and Bartonella in the same bite (bullshit, many tick samples on both costs show something like 2.6 pathogen average). In my personal experience, Bartonella is an absolute bitch to get rid of.

We need to better educate ourselves by owning all of our data in a way that enables us to submit it to research projects that are publically funded and not driven by patent revenue which pushes economies of scale. (off soapbox now :-)

Re: Lyme disease bacteria eradicated by new drug in early tests

#62
This has no bearing on the tests of this new drug, but it's worth noting that the best prevention is getting ticks off of you quickly.

I know this because I live in a very tick infested area (Ozark Mountains) and very few people who've grown up here in families that have lived here for generations get lyme disease. I don't personally know anyone who has.

Since I was kid in the `60s, and long before that, parents here did "tick checks" every evening. After calling us in mom's would strips us little kids down naked and pick any off they found and demand the older kids do it themselves and it becomes a habit. So does being aware. I mean, I don't ignore it when I think I feel one on me and I'm always aware there might be.

I'm 61 now and I've been bit more times than I can count, but I still make a point to do a tick check every evening.

Check out this video I made a couple years ago. They can get thick here...

https://youtu.be/TFVDv8swzxQ

Re: Lyme disease bacteria eradicated by new drug in early tests

#63
post #33

Earlier quoted context omitted.

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

Did you ever consider that the CDC guidelines for masks were intended to prevent hoarding so that those treating patients on the front lines could access them?

They should have told the truth. “Mask help but we don’t have enough of them. We need to reserve the few we have for doctors and nurses. People should use diy masks until we have more. It’s not perfect but it will still help to flatten the curve.“

Re: Lyme disease bacteria eradicated by new drug in early tests

#64

Earlier quoted context omitted.

Let's hope the FDA does its job of ensuring it is safe and actually works as its proponents say. I'd rather they not give it 737 MAX style review.

The issue is not "current practice" or "737 MAX," which is a false binary; the main issue is whether the FDA is optimally hitting the space between "safety" and "getting new drugs and treatments fast," and it appears that the FDA is overly conservative. See for example Launching the Innovation Renaissance https://marginalrevolution.com/marginalrevolution/2011/12/la...

Not sure that I understand the argument. The FAA is also clearly not hitting optimal space between "safety" and "getting new planes flying fast". Sometimes it appears the FDA hasn't been conservative enough, see Vioxx and labelling/guidance around opioids.

Re: Lyme disease bacteria eradicated by new drug in early tests

#65

Earlier quoted context omitted.

> Just like they are about the masks for covid-19 What is the CDC saying about masks for covid-19? Are you saying they're not effective or the CDC is downplaying their effectiveness?

Weeks ago the CDC lied, saying that masks aren't effective and that the general public shouldn't wear them. They did this ostensibly to keep the existing mask supply available only to medical workers. Needless to say, if they're ineffective for the general public, they're ineffective for doctors and nurses. And so people saw through the bullshit

I remember reading the CDC website, and I don't remember them saying that.

Their Jan 8 publication says:

> CDC currently recommends a cautious approach to symptomatic patients with a history of travel to Wuhan City. Such patients should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed. Personnel entering the room to evaluate the patient should use contact precautions and wear an N95 disposable facepiece respirator

- https://emergency.cdc.gov/han/HAN00424.asp

And on Feb 21 their FAQ said:

> Q: Does CDC recommend the use of facemask in the community to prevent COVID-19?

> A: CDC does not recommend that people who are well wear a facemask to protect themselves from respiratory illnesses, including COVID-19. You should only wear a mask if a healthcare professional recommends it. A facemask should be used by people who have COVID-19 and are showing symptoms. This is to protect others from the risk of getting infected. The use of facemasks also is crucial for health workers and other people who are taking care of someone infected with COVID-19 in close settings (at home or in a health care facility).

- https://wayback.archive-it.org/13529/20200221195555/https://...

So I'm not seeing where they ever said they were not effective. It says that if you are sick or showing symptoms you should wear a mask, but that they don't advise the general public to wear a mask because they are crucial to health care workers. To me this sounds like very good advice.

Re: Lyme disease bacteria eradicated by new drug in early tests

#66

Earlier quoted context omitted.

> Just like they are about the masks for covid-19 What is the CDC saying about masks for covid-19? Are you saying they're not effective or the CDC is downplaying their effectiveness?

Weeks ago the CDC lied, saying that masks aren't effective and that the general public shouldn't wear them. They did this ostensibly to keep the existing mask supply available only to medical workers. Needless to say, if they're ineffective for the general public, they're ineffective for doctors and nurses. And so people saw through the bullshit

> Needless to say, if they're ineffective for the general public, they're ineffective for doctors and nurses.

This isn't necessarily true. Doctors and nurses could have training on how to use masks, whereas most people will touch their faces more with them on.

Re: Lyme disease bacteria eradicated by new drug in early tests

#67
post #33

Earlier quoted context omitted.

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

Did you ever consider that the CDC guidelines for masks were intended to prevent hoarding so that those treating patients on the front lines could access them?

No, I think most of us realized that. It's still not OK for the CDC to lie to the public, regardless of motive. For a public health organization, the end doesn't justify the means.

Even more concerning are the number of doctors I've seen blatantly lying about the effectiveness of masks. Most people aren't idiots - if the masks help protect medical professionals from Covid-19, they can also help non-medical professionals.

The proper message would have been: masks can be effective, even a bandana can likely help prevent disease transmission. But it's important for Americans to save N95 masks for medical professionals until they're widely available. Given that it's highly likely that wearing any mask helps prevent the spread of the virus by keeping the mask wearer from transmitting it to others, this is what they should have done.

Re: Lyme disease bacteria eradicated by new drug in early tests

#68

Earlier quoted context omitted.

> Just like they are about the masks for covid-19 What is the CDC saying about masks for covid-19? Are you saying they're not effective or the CDC is downplaying their effectiveness?

Weeks ago the CDC lied, saying that masks aren't effective and that the general public shouldn't wear them. They did this ostensibly to keep the existing mask supply available only to medical workers. Needless to say, if they're ineffective for the general public, they're ineffective for doctors and nurses. And so people saw through the bullshit

This is seriously and dangerously wrong information.

Surgical masks are particularly helpful in stopping _infected_ people from spreading the disease.

New information and data on asymptomatic spreaders means that the CDC (and many other Western health authorities) are considering changing their advice. The idea is that everyone must assume they are an asymptomatic spreader.

Additionally, surgical masks aren't the only PPE that medical workers use to protect themselves. Furthermore, hospitals and medical workers need surgical masks for many different non-coronavirus activities.

See here for more info:https://www.npr.org/sections/health-shots/2020/03/31/8245604...

Re: Lyme disease bacteria eradicated by new drug in early tests

#69
post #53

Earlier quoted context omitted.

> Just like they are about the masks for covid-19 What is the CDC saying about masks for covid-19? Are you saying they're not effective or the CDC is downplaying their effectiveness?

CDC plain saying they are not effective and not recommending them

Wrong. It's much more nuanced than that.

Surgical masks are not effective at preventing infection. They are effective at spreading infection.

New data on asymptomatic spreaders means than public health authorities are considering changing their advice. The default assumption would then be that everyone has it, and should therefore wear a mask to prevent spreading it.

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