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Lyme disease bacteria eradicated by new drug in early tests

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Re: Lyme disease bacteria eradicated by new drug in early tests

#41
post #33

Note that they're carefully dancing around the elephant in the room: As far as I know, no one has ever demonstrated that Lyme spirochetes survive a course of standard antibiotics (Emphasis mine): > Standard treatment of Lyme disease is oral antibiotics, typically doxycycline, in the early stages of the disease; but for reasons that are unclear, the antibiotics don't work for up to 20% of people with the tick-borne il…

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

The linked study's lead author is Middelveen. Isn't she the one who tried to say Lyme is an STD a few years back? I know nothing about the linked study, haven't read it, but her sloppiness with scientific rigor makes me nervous about taking the abstract at face value...

Re: Lyme disease bacteria eradicated by new drug in early tests

#42
This is neat, very curious about how this process has been scaled/automated:

>>> This process entails acquiring "libraries" of thousands of known chemical compounds and drugs, then mixing Lyme bacteria with each in tiny wells to see which ones are best at killing the organisms. The best drug candidates were retested in larger culture dishes, then the safest of these were tested in vivo in seven mice.

Re: Lyme disease bacteria eradicated by new drug in early tests

#43
post #36

Note that they're carefully dancing around the elephant in the room: As far as I know, no one has ever demonstrated that Lyme spirochetes survive a course of standard antibiotics (Emphasis mine): > Standard treatment of Lyme disease is oral antibiotics, typically doxycycline, in the early stages of the disease; but for reasons that are unclear, the antibiotics don't work for up to 20% of people with the tick-borne il…

Lyme disease talk just makes me think of Nicholas Zakas and then I get bummed out. I know there's a guy, or maybe he represents a group of researchers, who thinks that Chronic Fatigue Syndrome is caused by inflammation in the brain, either due to some undetectable infection, or just a misfiring that is a lingering effect of some other insult (sounds to me like a histamine response aka allergy). If your body thought y…

I really enjoy your writing style. Flows extremely well.

Re: Lyme disease bacteria eradicated by new drug in early tests

#44
post #8

Has anyone tested hydroxychloroquine against Lyme disease?

ah yes, the flavor of the month drug. What makes you think it'd work on Lyme.

Did we have any reason to think it would work on corona? (I really don’t know)

Re: Lyme disease bacteria eradicated by new drug in early tests

#45
post #34

Earlier quoted context omitted.

Sorry I meant IgM not IgG.

The page says that: "Positive IgM results should be disregarded if the patient has been ill for more than 30 days." The reason may be this: https://www.sciencedirect.com/science/article/pii/S1198743X1...

Thanks for responding. But that study says they assumed the results were false positives.

Maybe for the purpose of that paper that’s fine. But I’m not sure if it supports your statement.

Re: Lyme disease bacteria eradicated by new drug in early tests

#46

Earlier quoted context omitted.

ah yes, the flavor of the month drug. What makes you think it'd work on Lyme.

Did we have any reason to think it would work on corona? (I really don’t know)

Yes, it is an antiviral.

Re: Lyme disease bacteria eradicated by new drug in early tests

#47

Earlier quoted context omitted.

ah yes, the flavor of the month drug. What makes you think it'd work on Lyme.

Did we have any reason to think it would work on corona? (I really don’t know)

We still have no good evidence that is does work for SARS-CoV-2.

Re: Lyme disease bacteria eradicated by new drug in early tests

#48
post #33

Note that they're carefully dancing around the elephant in the room: As far as I know, no one has ever demonstrated that Lyme spirochetes survive a course of standard antibiotics (Emphasis mine): > Standard treatment of Lyme disease is oral antibiotics, typically doxycycline, in the early stages of the disease; but for reasons that are unclear, the antibiotics don't work for up to 20% of people with the tick-borne il…

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

> Just like they are about the masks for covid-19

What is the CDC saying about masks for covid-19? Are you saying they're not effective or the CDC is downplaying their effectiveness?

Re: Lyme disease bacteria eradicated by new drug in early tests

#49
post #33

Note that they're carefully dancing around the elephant in the room: As far as I know, no one has ever demonstrated that Lyme spirochetes survive a course of standard antibiotics (Emphasis mine): > Standard treatment of Lyme disease is oral antibiotics, typically doxycycline, in the early stages of the disease; but for reasons that are unclear, the antibiotics don't work for up to 20% of people with the tick-borne il…

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

Did you ever consider that the CDC guidelines for masks were intended to prevent hoarding so that those treating patients on the front lines could access them?

Re: Lyme disease bacteria eradicated by new drug in early tests

#50
post #33

Earlier quoted context omitted.

Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease. >RESULTS: Motile spirochetes identified histopathologically as Borrelia were detected in culture specimens, and these spirochetes were genetically identified as Borreliaburgdorferi by three distinct polymerase chain reaction (PCR)-based approaches. Spirochetes identified as Borrelia burgdorferi were cultured from the blood of seven subje…

Did you ever consider that the CDC guidelines for masks were intended to prevent hoarding so that those treating patients on the front lines could access them?

right but everyone is out and about. while people in asian wore masks when they went grocery shppping. i get what they did but they screwed civilians for sure in the name of saving doctors. they actively lied about them being needed so one group would have a better chance. the truth is if you were going to have any contact with someone you needed a mask.
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