Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial • Hacker News Board

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#31

Post by starkd » Thu, Apr 02, 2020, 2:52 PM UTC

karl11 wrote: post #19

Based on this and all the other anecdotal studies plus all the people treated with it for other ailments, it seems fairly certain that at a minimum this treatment is not causing more harm. Given that plus all the indications that it seems to help to some degree, we should be pursuing production scale of these drugs aggressively. It is very unfortunate that the media politicized this treatment in such a way that now e…

It's quite remarkable to see the media more focused on how they are supposed to oppose Trump rather than just reporting the news.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#32

Post by JshWright » Thu, Apr 02, 2020, 2:52 PM UTC

_red wrote: post #16

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

Face it, HCQ is an old and cheap drug that doesn't fit Big Pharma profit visions. Its much more enticing for Big Pharma to sell new patented solutions, so they will pay their PR mouthpieces (MSM) to "be cautious" of anything that doesn't achieve that end goal.

> Face it, HCQ is an old and cheap drug that doesn't fit Big Pharma profit visions.

That seems like a non sequitur... Do you think HCQ knows that, and is therefore making itself less effective, just to stick it to Trump?

The reality is, HCQ is not without adverse side-effects, and we have reason to be cautious. There have been several examples in the past where early results of HCQ testing looked promising against various viruses, but didn't pan out when actually used at larger scale in humans.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#33

Post by _ea1k » Thu, Apr 02, 2020, 2:52 PM UTC

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

That is not at all a fair assessment of what happened. I won't blame specific groups (there is plenty of fault to go around), but it wasn't the administration that made things partisan there.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#34

Post by caconym_ » Thu, Apr 02, 2020, 2:52 PM UTC

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

I think Trump was just casting about for anything he might hitch his wagon to and claim credit for later. It's unfortunate that "the other side" heaped so much scorn on chloroquine just because Trump was touting it, because there was never any conclusive evidence that it doesn't work, and if it actually does work then they played right into Trump's usual "hoax" angle.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#35

Post by bart_spoon » Thu, Apr 02, 2020, 2:53 PM UTC

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

How did they turn it into a partisan issue? Trump announced in a press conference that hydroxychoroquine held promise as a potential therapy based on anecdotal evidence being shared by physicians in Asia and Europe. Everyone, Democrats, the media, and individuals jumped on him as promoting snake oil and having no basis for his claims. It was barely news when he announced it. Some of the same evidence he was referencing in his claims had been circulating in preprints and on subs like r/COVID19 for weeks at that point.

I strongly dislike the administration generally, but I've been perplexed as to how eager everyone has been to attack him over this particular incident. And if it was made partisan, it seems like it was done so by others, and not the administration itself.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#36

Post by shakezula » Thu, Apr 02, 2020, 2:54 PM UTC

_ea1k wrote: post #33

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

That is not at all a fair assessment of what happened. I won't blame specific groups (there is plenty of fault to go around), but it wasn't the administration that made things partisan there.

The President literally called it a "Democrat hoax"

How is it not the administration's doing then?

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#37

Post by Mountain_Skies » Thu, Apr 02, 2020, 2:55 PM UTC

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

Look in the mirror to see how this became a partisan issue. The president made absolutely no partisan statements when mentioning his hope for the drug. It was those looking through dirt colored glasses that took things down that path.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#38

Post by Justsignedup » Thu, Apr 02, 2020, 2:55 PM UTC

bart_spoon wrote: post #35

D13Fd wrote: post #11

I wish the current U.S. administration hadn't tried to turn this into a partisan issue.

How did they turn it into a partisan issue? Trump announced in a press conference that hydroxychoroquine held promise as a potential therapy based on anecdotal evidence being shared by physicians in Asia and Europe. Everyone, Democrats, the media, and individuals jumped on him as promoting snake oil and having no basis for his claims. It was barely news when he announced it. Some of the same evidence he was referenci…

He heard something about these two drugs, and without any scientific evidence he announced it, causing a panic-grab for the drugs. Unfortunately even the CDC was saying we don't have evidence supporting it.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#39

Post by bart_spoon » Thu, Apr 02, 2020, 2:56 PM UTC

davidw wrote: post #12

Seems relevant: https://twitter.com/SquawkCNBC/status/1245669685267439616 Not sure they've been doing proper studies and such because they're so slammed, but it seems they've been trying it in Italy and... maybe it helps some, but doesn't seem like it works miracles.

Some of the papers being shared on r/COVID19 seem to be indicating that perhaps it has little effect once the disease has gotten severe, but if taken early, may reduce potential severity and time to recovery. Still early, but it seems like, if the results end up being true, it could be helpful in stemming the tide of the disease.

Re: Efficacy of hydroxychloroquine in patients with Covid-19: a randomized trial

#40

Post by airstrike » Thu, Apr 02, 2020, 2:57 PM UTC

Justsignedup wrote: post #38

bart_spoon wrote: post #35

Earlier quoted context omitted.

How did they turn it into a partisan issue? Trump announced in a press conference that hydroxychoroquine held promise as a potential therapy based on anecdotal evidence being shared by physicians in Asia and Europe. Everyone, Democrats, the media, and individuals jumped on him as promoting snake oil and having no basis for his claims. It was barely news when he announced it. Some of the same evidence he was referenci…

He heard something about these two drugs, and without any scientific evidence he announced it, causing a panic-grab for the drugs. Unfortunately even the CDC was saying we don't have evidence supporting it.

That's valid criticism, but it has nothing to do with partisanship.