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Bosch develops rapid test for Covid-19

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161–170 of 190 posts

Re: Bosch develops rapid test for Covid-19

#161
post #24

Earlier quoted context omitted.

The full quote does one extra thing, it implies that buying 100+ of these machines is totally expected.

Can these machines do anything else after we're done with Covid-19? I assume they can run other tests?

There is a chance we will never be done with COVID-19.

Re: Bosch develops rapid test for Covid-19

#162

Earlier quoted context omitted.

...marketing material? To the non-English world? I was literally just explaining a potentially helpful thought process to an English-speaking HN visitor dev who lists his(?) public key on his profile... not trying to produce marketing material for a French waiter or something. Are you sure you're not the one confused here rather than him?

I'm only trying to point out that Bosch may have specifically chosen the term 'accuracy' instead of 'specificity' or 'sensitivity', which don't translate easily outside of the Anglo-sphere, and in my opinion your thread is a valid example of why those two terms don't get used to market this device, which is what kicked this thread off in the first place ..

It is more likely that they were trying do deliberatly write a vague statement, their (native) German announcement uses the same "Genauigkeit", instead of the relevant terms "Sensitivität" and "Spezifizität".

Re: Bosch develops rapid test for Covid-19

#163
post #68
post #61

How is this better than Open qPCR which is 3-times less expensive and can give a test result in 1 hour instead of 2.5 hours?

Does 'Open' mean open source? Is there a free/open-source PCR design that DIYers can build themselves as long as they have the parts/resources?

For OpenPCR yes, for Open qPRC not.

Re: Bosch develops rapid test for Covid-19

#164
post #156

Earlier quoted context omitted.

Thank you so much for explaining exponential growth to me. > Nobody has thousandfold more hospital beds and doctors ready, even less a million times more, which is the two month's growth. And in a few additional months, we will need more ICU beds than the number of atoms in the universe. Infection rates are already significant, there just aren't enough people to sustain two months' growth.

> Infection rates are already significant, there just aren't enough people to sustain two months' growth. This is wrong, of course there are enough people for this to grow for months even with no containment efforts. https://www.imperial.ac.uk/media/imperial-college/medicine/s...

That model is 10 days old, and already out of date. Look at the one they've released yesterday.

Again, these models are not robust to minor changes in their assumptions.

Re: Bosch develops rapid test for Covid-19

#165
post #98

This is not rapid, only 10 tests/day, whilst the current overly slow sequencers can do 200/day. The accuracy of 5% is also worse than other faster sequencers of 3%. And compare that to modern ThermalFischer parallel PCR sequencers, which operate in realtime, 25 tests in parallel, for 2.500€. That's a factor of 1000. With 10 modern sequencers per city you could test 10.000 per day, eg with drive-in. https://www.thermo…

Honest question, are you speaking from experience? We run PCRs at our company for our vaccine research and having to run them back-to-back day-in-day out, without any manual errors, is going to be super stressful for any lab. Not to mention the costs of training healthcare personnel on how to run a PCR.

Re: Bosch develops rapid test for Covid-19

#166

This test is made for use at the point of care, apparently all the operater has to do is insert a swab into a cartridge and put it into the device. [0] Comparing the throughput to fully automated systems used in testing labs [1] (look at this beast!) or qPCR machines in research labs [2] is missing the point, those require high investment or skilled staff. A test that can be run quickly by any doctor would be very us…

Yeah, consumables cost is always the bug-bear for single use tech. Also, the cost of disposal/incineration can balloon up significantly.

Re: Bosch develops rapid test for Covid-19

#168
post #98

This is not rapid, only 10 tests/day, whilst the current overly slow sequencers can do 200/day. The accuracy of 5% is also worse than other faster sequencers of 3%. And compare that to modern ThermalFischer parallel PCR sequencers, which operate in realtime, 25 tests in parallel, for 2.500€. That's a factor of 1000. With 10 modern sequencers per city you could test 10.000 per day, eg with drive-in. https://www.thermo…

In addition to all information above this test is able to detect antibodies only not virus. So it is not recommended tests by WHO. This test is only useful in the later part of infection by the time which patient might have in contact with others thus spreading the disease. We need tests which can detect single of very few virus particle in the early stage of infection and that will help to quarantine the patient thu…

I'm not sure this is true. Bosh's site says "Which detection method is used in Bosch’s COVID-19 test? The COVID-19 test is based on a combination of sample preparation (including process controls): Multiplex PCR (Polymerase-Chain-Reaction), μArray-detection to allow the identification of SARS-CoV-2."

Re: Bosch develops rapid test for Covid-19

#169
post #24
post #16

Earlier quoted context omitted.

The full quote is "A Bosch Vivalytic analyzer can perform up to ten tests in the space of 24 hours. This means it takes just 100 devices to evaluate up to 1,000 tests per day." which makes more sense, the 100 devices is just an example. But I agree that it's largely unnecessary, the initial "up to ten tests per day" would have been enough.

The full quote does one extra thing, it implies that buying 100+ of these machines is totally expected.

Obviously its implied because that's the influx of patients a lot of hospitals are seeing.

Re: Bosch develops rapid test for Covid-19

#170
post #9

Earlier quoted context omitted.

"(...)the rapid test can detect a SARS-CoV-2 coronavirus infection in patients in under two and a half hours" (...)With the tests currently in use, patients must usually wait one to two days for a result." Well i see here a big improvement...

> With the tests currently in use, patients must usually wait one to two days for a result. Is that because it takes 2 days for the test to complete, or because there a 2 day delay from backlog + administrative time?

usually shipping the samples to a lab. this test can be done on the spot in the hospital by a doctor.
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