The good news: IE use is down over the last year to only about 40%.
The bad news: the growth elsewhere is all Chrome, with less than 1% Firefox or Safari. There’s a tiny sprinkling of Edge, as well, but I forget the numbers on that.
Our users are state and county offices and medical facilities, rather than private individuals, so the users are somewhat captive to whatever their organization mandates.
The only browser detection we do is in client side scripting to detect if the browser can directly display a PDF inline (or not, in the case of IE11)