I looked at Jitsi recently as I was thinking about self-hosting it (I have the bandwidth).
My concerns:
It seems to be based on XMPP and require an XMPP server. They offer a quick-start guide on configuring it however I am not sure how secure the default configuration is - I'm worried the quick start guide is about "get it working", not "make it secure" and I don't have XMPP knowledge nor the desire to learn a complicated protocol just to be able to run this securely.
Why does it need an XMPP server? I do not want nor care about XMPP and everyone will be joining via browsers anyway. As far as I'm concerned it's just one (very big) moving part that I don't want to be responsible for.
Overall it left a sour & sad taste in my mouth. There's no way I'm putting this thing on the public Internet; the attack surface seems too large and too many opportunities to screw it up.