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Covid-19’s stop-gap solution until vaccines and antivirals are ready

globalhealthnow.org

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Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#101

Post by tyingq »

funcDropShadow wrote: post #100
tyingq wrote: post #86

"Yes. In fact, the Chinese sent 90 tons of plasma to Italy." That's impressive. I wonder how many individual donations that maps to. And how many people that could treat. Edit: Trying to answer my own question. Typical blood donation is 470ml. That weighs about 0.5 kilograms. Plasma is roughly half of what's in your blood, so half that again... 0.25 kilograms. So assuming they meant metric ton (1000Kg), 4000 individu…

There don't exist 360.000 recovered humans at the moment. At least officially.

Yeah, that's why I keep looking at my math, though it seems straightforward. That 90 tons must be off somehow.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#102

Post by [deleted] »

tyingq wrote: post #86

"Yes. In fact, the Chinese sent 90 tons of plasma to Italy." That's impressive. I wonder how many individual donations that maps to. And how many people that could treat. Edit: Trying to answer my own question. Typical blood donation is 470ml. That weighs about 0.5 kilograms. Plasma is roughly half of what's in your blood, so half that again... 0.25 kilograms. So assuming they meant metric ton (1000Kg), 4000 individu…

[deleted]

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#103

Post by jeltz »

agumonkey wrote: post #68
tcbawo wrote: post #43

Some emerging theories of pathology suggest that lung function can be increased by reinflating collapsed alveoli with constant pressure: https://emcrit.org/pulmcrit/cpap-covid/ . It describes cases where oxygen supplementation could be reduced or eliminated. This development ( https://www.isinnova.it/easy-covid19-eng/ ) looks very promising for 'sub-intensive' cases -- adapting decathlon mask/snorkel with a 3D printe…

I don't know where to ask.. is vaporized cbd helpful ? it's said to be a potent anti inflammatory compounds and also help cleansing cells through apoptosis.

I am not a doctor but if it is indeed anti-inflammatory and causes apoptosis it sounds more likely to be harmful than to be helpful. I suspect apoptosis (or rather what happens is that cells get hijacked by the virus and then the immune systems kills the hijacked cells) is what causes most of the lung damage and inflammation is an important part of the response from the immune system so I would not mess with that more than necessary.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#104

Post by tyingq »

alok-g wrote: post #72

Does someone know how much of this needs to be injected to be effective?

Not a real answer, but the article says one person can treat two people. So somewhere around 0.25 to 0.35 liters is a rough guess, assuming "one person" means "one typical blood product donation".

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#105

Post by alok-g »

tyingq wrote: post #104
alok-g wrote: post #72

Does someone know how much of this needs to be injected to be effective?

Not a real answer, but the article says one person can treat two people. So somewhere around 0.25 to 0.35 liters is a rough guess, assuming "one person" means "one typical blood product donation".

Got you. Thanks.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#106

Post by to1y »

hnick wrote: post #53
vkou wrote: post #46

Earlier quoted context omitted.

> This crisis is the first event in my lifetime that's given me any optimism about our ability, as a global civilization, to solve problems and get things done. Based on what? What I see is the same scenario play out over and over again, from one country to another, delayed by a week, or two, or three, with most of them making the same mistakes that their predecessors made. Nobody in the West lifted a finger to prepa…

Too little too late sums it up in Australia. Schools are still open (there are good reasons, but by the time those reasons become not-good, it will be too late). At least the states and cities are taking over leadership where the federal level has failed.

What was expected? We've seen time and time again our politicians are incapable of action. Any moderately unexpected situation seems to be brushed under the rug or gets palmed off to the capable Canadians. The true 'dole bludgers' who have metastasized themselves in the sea of bullshit bureaucracy. Fine they steal from the country and waste tax payers funds incessantly. If they could atleast be capable of making decisions.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#107

Post by DigitalSea »

tyingq wrote: post #101
funcDropShadow wrote: post #100

Earlier quoted context omitted.

There don't exist 360.000 recovered humans at the moment. At least officially.

Yeah, that's why I keep looking at my math, though it seems straightforward. That 90 tons must be off somehow.

Presumably, they also have to keep the plasma cool, I am guessing some of that 90-tonne wait could be attributed to cooling gels/liquids of some kind to keep it stable for transport. Admittedly, I don't know how they would even transport this over long distances like that.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#108

Post by fulafel »

kjaftaedi wrote: post #92
samsonradu wrote: post #76

My knowledge about industrial manufacturing is slim to none so can someone explain please why is it not possible to (globally) ramp up production of face masks and ventilators to a virtually unlimited quantity? What exactly is the bottleneck? Are we lacking materials, labour or the technical know-how? Are the factories currently producing them so advanced and hard to reproduce?

Regular masks it is possible to ramp up production. N95 masks, it is not easily possible to ramp up production in a short time frame. This article explains it well: https://www.npr.org/sections/goatsandsoda/2020/03/16/8149292...

N95 just means anything that can filter out 95% of nacl in a specific test, the implementation is not constrained to this type of fabric. There are other ways of doing it.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#109

Post by rurban »

Antivirals are ready. HCQ was mass produced for decades, and ramping it up is trivial, and already done.

The first vaccines, BGM, will be ready in summer. This was already applied en masse in the UK in the 60ies, and is in stage 3 testing.

What else: Vitamin C is ready.

Self made masks are better than no masks.

Ramping up tests kits are the most important part until summer. There's a new faster one in testing, which needs 20min, and will cost €15.

Contact-less thermometers can be imported en masse from China.

Creating antibodies from plasma is not really viable for billions. The rest is.

Re: Covid-19’s stop-gap solution until vaccines and antivirals are ready

#110

Post by rurban »

fulafel wrote: post #80
samsonradu wrote: post #76

My knowledge about industrial manufacturing is slim to none so can someone explain please why is it not possible to (globally) ramp up production of face masks and ventilators to a virtually unlimited quantity? What exactly is the bottleneck? Are we lacking materials, labour or the technical know-how? Are the factories currently producing them so advanced and hard to reproduce?

Same as many other problems (eg global warming) - the market economy can't deliver a solution because it's not short teem profitable for the relevant actors.

We are expecting a global economy crisis, much bigger than the last wallstreet crash. There needs to be a solution in the next 6 weeks, not 6 months. Because by then we'll have a bankrun and global shutdown of social behavior.

Profitability needs to look into the next 6 months, not just 2 weeks. And btw, we don't do market economy here anymore. The UK tried and gave up 2 days ago. They are all in centralized crisis mode.

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