I’m honestly looking forward to a new economy served by large corporations. Large companies are more consistent in their user experience across multiple locations, and are better buyers of tech. They are always looking for new ways to automate their operations and frequently turn to tech companies to solve their problems at scale. So in a way, it’s good for the valley if more of the economy becomes more corporate.
/s ?
People often romanticize the "mom & pop" places, but there's a reason that most consumer-facing companies are very large, and those reasons were enumerated by the OP.
Also, there's a good deal of selection bias going on. If you had a successful business, why wouldn't you look to expand it to multiple locations? Running a single store makes your business vulnerable and usually requires a lot of time.