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Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

reuters.com

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Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#91

Post by jshevek »

SpikeDad wrote: post #68
peterburkimsher wrote: post #55

Earlier quoted context omitted.

This is anecdata, so beware. For a full story, email me. I have minor symptoms, and have been self-isolating since Wednesday (18) because many people around me were coughing on Monday (16) & Tuesday (17). The government here in NZ has not issued any lockdown instructions. Due to comments here on HN, I decided to buy 4x 1.5 litres of ordinary Schweppes tonic water. Panic buying had not yet struck (it has now, but most…

I hope the admins here remove this post immediately. This is dangerously false advice based on absolutely nothing but one ridiculous presumption. If people listen to you they're truly ill informed.

He is sharing his personal experience. He is not making unreasonable claims. His recommendation, to his friends, is not dangerous.

No one should mistake this as an alternative to proper treatment.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#92

Post by gjs278 »

SpikeDad wrote: post #68
peterburkimsher wrote: post #55

Earlier quoted context omitted.

This is anecdata, so beware. For a full story, email me. I have minor symptoms, and have been self-isolating since Wednesday (18) because many people around me were coughing on Monday (16) & Tuesday (17). The government here in NZ has not issued any lockdown instructions. Due to comments here on HN, I decided to buy 4x 1.5 litres of ordinary Schweppes tonic water. Panic buying had not yet struck (it has now, but most…

I hope the admins here remove this post immediately. This is dangerously false advice based on absolutely nothing but one ridiculous presumption. If people listen to you they're truly ill informed.

I hope admins ban you for advocating withholding information

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#93

Post by prostheticvamp »

SpikeDad wrote: post #57
blhack wrote: post #52

Earlier quoted context omitted.

I don't mean and disrespect to you as a physician, but there appear to be many experts who disagree with you to the point of acting out their disagreement at scale. Chloroquine has become a standard part of treatment for this disease in several countries, and its continued use seems to imply its efficacy.

Haha. Continued use seems to imply it's efficacy. This might be the most illogical post on Hacker News in some time. I think we could have a whole website of things that were continued to be used without a shred of evidence of effectiveness.

We could also have a whole website of things people strongly believed were effective that RCTs absolutely demolished.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#94

Post by prostheticvamp »

blhack wrote: post #52
prostheticvamp wrote: post #33

Earlier quoted context omitted.

Medical doctor and statistician weighing in just to say: I agree fully with what you wrote. No miracles observed.

I don't mean and disrespect to you as a physician, but there appear to be many experts who disagree with you to the point of acting out their disagreement at scale. Chloroquine has become a standard part of treatment for this disease in several countries, and its continued use seems to imply its efficacy.

Its use in the presence of a plausible mechanism, and in the absence of any good supporting data, does not indicate efficacy. It indicates that when a patient is circling the drain you throw things at the wall that could plausibly have some benefit.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#95

Post by chimichangga »

paulmd wrote: post #72
snowwrestler wrote: post #41

Earlier quoted context omitted.

To those who aren't aware of it, the reason someone thought to try this is that this type of drug has shown intermittent promise in treating viral infections for years. But to date it has never really panned out in clinical trials. (If it had, we would all be taking chloroquine every time we caught a serious virus like the flu). Doesn't mean it can't be beneficial this time for this particular virus; we should always…

> To those who aren't aware of it, the reason someone thought to try this is that this type of drug has shown intermittent promise in treating viral infections for years. No, the actual reason is that Chinese doctors noted a statistical abberation in their coronavirus patients: none of the patients had lupus. They called around and confirmed it, none of the hospitals had any patients with lupus. And the standard chin…

chloroquine and remdesivir, have been designated for Expanded Access, or “compassionate use,” by the FDA. Hopefully to be FDA approved for the gp soon.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#96

Post by snowwrestler »

paulmd wrote: post #72
snowwrestler wrote: post #41

Earlier quoted context omitted.

To those who aren't aware of it, the reason someone thought to try this is that this type of drug has shown intermittent promise in treating viral infections for years. But to date it has never really panned out in clinical trials. (If it had, we would all be taking chloroquine every time we caught a serious virus like the flu). Doesn't mean it can't be beneficial this time for this particular virus; we should always…

> To those who aren't aware of it, the reason someone thought to try this is that this type of drug has shown intermittent promise in treating viral infections for years. No, the actual reason is that Chinese doctors noted a statistical abberation in their coronavirus patients: none of the patients had lupus. They called around and confirmed it, none of the hospitals had any patients with lupus. And the standard chin…

I would give it a shot too if I was sick, but that is a far cry from calling it a miracle.

It shows promise and should be pursued—and it is. Let’s not oversell it though.

> there's lots of drugs like tylenol that we know to be horribly unsafe and yet they remain OTC anyway

Interestingly, one of the other therapeutic leads that doctors are following up on is whether Tylenol is safer than ibuprofen for Covid patients. It got reported that it was, but it’s not yet clear how true that is.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#98

Post by SpikeDad »

robocat wrote: post #83
SpikeDad wrote: post #68

Earlier quoted context omitted.

I hope the admins here remove this post immediately. This is dangerously false advice based on absolutely nothing but one ridiculous presumption. If people listen to you they're truly ill informed.

You are seriously overreacting. He is suggesting drinking a few glasses of tonic water, saying why it is helping him, and prefixed a warning. There is nothing dangerous in his suggestion, and it is obviously not given as a complete medical solution to the epidemic to use for your family.

You didn't read it. He's giving people this advice. It's dangerous advice. I am not overreacting. This is a time for solid, real medical information and not anecdotal folklore.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#99

Post by SpikeDad »

prostheticvamp wrote: post #93
SpikeDad wrote: post #57

Earlier quoted context omitted.

Haha. Continued use seems to imply it's efficacy. This might be the most illogical post on Hacker News in some time. I think we could have a whole website of things that were continued to be used without a shred of evidence of effectiveness.

We could also have a whole website of things people strongly believed were effective that RCTs absolutely demolished.

RCT? Sorry don't know that abbreviation.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#100

Post by morninglight »

Starting back in the 60's, hundreds of thousands of Americans serving in the military and peace corps in areas with malaria were given daily chloroquine for extented periods of time. Think Vietnam. How long does it take to evaluate safety?
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