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Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

reuters.com

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Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#61

Post by SpikeDad »

blhack wrote: post #54
jacquesm wrote: post #50

Earlier quoted context omitted.

> Sounds like the next Forsythia. For those that don't get the reference: https://en.wikipedia.org/wiki/Contagion_(2011_film) And that's exactly what it is.

Oh come on that isn't fair. Just do a simple google search for countries which have made chloroquine part of their standard treatment. The reference you're making here is to a person trying to exploit people during a pandemic with what was an obvious lie. This is not that.

A country using an unproven treatment to quell panic is hardly unprecedented nor out of the realm of many governments and sorry for me to say the US as well.

"Lets all pray for God to cure us" comes to mind.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#62

Post by jjjensen90 »

viggity wrote: post #20

Does anyone know how quickly the production of Chloroquine Phosphate and Hydroxychloroquine can be ramped up (say, to the tune of 500M people * 7g per "course" = 3.5 million kilograms? I tried finding out how much chloroquine is prescribed world wide per year, but couldn't find it. It may give us a clue into how much is already being used. I know that it isn't used except for pregnant women as a malaria treatement be…

From what I understand, it is a very cheap and easy drug to manufacture, having been designed for mass production in a previous era, as well as being a relatively simple chemical formula (some hydrocarbons, amines, a chloride?).

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#63

Post by jerrysievert »

baron_harkonnen wrote: post #13
Etheryte wrote: post #8

Earlier quoted context omitted.

I can't find the thread right now, but someone did a back of the napkin calculation that you'd need to have 200 gin tonics a day to reach any kind of a reasonable level.

Oh I hope someone can make some original strength tonic water and then g&ts can be of medical value once again!

https://www.jeffreymorgenthaler.com/how-to-make-your-own-ton...

you can buy the cinchona bark on amazon, recipe is very good.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#64

Post by jacquesm »

blhack wrote: post #54
jacquesm wrote: post #50

Earlier quoted context omitted.

> Sounds like the next Forsythia. For those that don't get the reference: https://en.wikipedia.org/wiki/Contagion_(2011_film) And that's exactly what it is.

Oh come on that isn't fair. Just do a simple google search for countries which have made chloroquine part of their standard treatment. The reference you're making here is to a person trying to exploit people during a pandemic with what was an obvious lie. This is not that.

You are harping on the theme of 'a miracle cure' in this thread. I think you're highly irresponsible.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#65

Post by pbreit »

wazoox wrote: post #48

Warning: chloroquine has strong side-effects, and very high toxicity, unfortunately pretty close to therapeutic doses, that may cause serious arrhythmia, and even heart attacks. Don't ever try to self-medicate with chloroquine.

WARNING: the above is almost certainly wrong. Citation should be provided.

The preponderance of the evidence suggests that it's a well-understood drug that has been around for decades, used by 10s of millions for not only malaria but also arthritis. In fact it is safe enough that it is available over the counter in some countries. [1]

1: https://en.wikipedia.org/wiki/Chloroquine

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#67

Post by Spare_account »

jessaustin wrote: post #18
turndown wrote: post #5

Earlier quoted context omitted.

Considering there is no edit on the original post, the answer has been in it since you asked the question.

How can we tell if HN comments have been edited? [I have now edited... but please don't say "I see that you added something in brackets"]

Can you please edit this one and I'll tell you what I see

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#68

Post by SpikeDad »

peterburkimsher wrote: post #55
robocat wrote: post #15

Earlier quoted context omitted.

Wikipedia: In the United States, the US Food and Drug Administration (FDA) limits the quinine content in tonic water to 83 ppm[3] (83 mg per liter if calculated by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg,[4] and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult). How much less than 83mg/litre is unclear. You would do yourself damage…

This is anecdata, so beware. For a full story, email me. I have minor symptoms, and have been self-isolating since Wednesday (18) because many people around me were coughing on Monday (16) & Tuesday (17). The government here in NZ has not issued any lockdown instructions. Due to comments here on HN, I decided to buy 4x 1.5 litres of ordinary Schweppes tonic water. Panic buying had not yet struck (it has now, but most…

I hope the admins here remove this post immediately. This is dangerously false advice based on absolutely nothing but one ridiculous presumption.

If people listen to you they're truly ill informed.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#69

Post by capkutay »

I wouldn't say 'take this with a grain of salt', but I also wouldn't brush it off as fake either. Yes, the french study wasn't structured perfectly. But such a trial isn't possible in the timeframe we're looking at.

If enough respected virologists (like Didier Raoult) and doctors in China/South Korea see some positive signals, it makes sense to prepare for the event that it does indeed help. Keep in mind, this is already being used as a treatment in the US today. They likely have even better data than we do. Or if they don't, they still feel like it's worth taking a calculated risk on.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#70

Post by teddyvangogh »

jacquesm wrote: post #40

WARNING: To all those who are reading threads like these and intend to self medicate: you should not do this unless you are medically qualified or have a doctor prescribe you whatever medication might help. The risk of side effects is substantial and there is a reason many countries keep quack laws on the book to go after those who practice medicine without a license. Medical advice should be given by doctors and wha…

chloroquine is prescription only in the US.
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