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Chloroquine has shown apparent efficacy in treatment of Covid-19

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Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#251
post #23

Earlier quoted context omitted.

Yes my daughter got it on a trip to Tanzania last year.

Then you should go after the doctor for malpractice because malaria in East Africa is hydrochloroquine-resistant.

That’s the least bit of malpractice I’ve seen in the past year.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#254
Poland has formally registered Chloroquine as a drug for COVID-19 and will treat all patients with it. Chloroquine phosphate is a generic antimalarial drug derived from quinolone, in 10 trials for Covid-19 in China, including one in combination with Kaletra, as chloroquine phosphate is believed to have broad-spectrum antiviral activities.

Basically the goal is to allow zinc to get into a cell, it needs a helper to get inside the cell (a Zinc Ionophore). Apparently Hydroxychloroquine / Plaquenil (which you can buy here: InHousePharmacy.vu/p-1106-plaquenil-tablets-200mg.aspx or here easyshopping4health.com/buy-plaquenil-usa.html) is even more effective than Chloroquine.

Also see Medscape.com/viewarticle/736439 and https://www.ncbi.nlm.nih.gov/pubmed/32074550/ title: "Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies"

Quinolones like Chloroquine were used in malaria prevention for many, many years. they aren't used specifically against malaria anymore, because malaria adapted. But I always prefer a compound that can be manufactured easily and has been used by many many people over years.

Regarding Zinc Ionophores, the flavonoid Quercetin (which you can buy in many places) has been shown to rapidly increase labile zinc in mouse cells as well as in liposomes. Source: https://pubs.acs.org/doi/abs/10.1021/jf5014633

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#255

Earlier quoted context omitted.

And as discussed previously before in many submissions, hydroxichloroquine is already actively being used against Covid19 by at least the following EU countries: - Belgium - Netherlands - Switzerland - Italy

any source for this? especially how the success rate is in Italy? How many people received it etc.?

Sure look at my comments on other threads

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#256

Quercetin is over-the-counter and has similar properties Studies according to the video below on Ebola and Zikka used 50-100mg/KG - a lot lot. This Medcram video talks about Chloroquine and the others: https://www.youtube.com/watch?v=vE4_LsftNKM

> Quercetin is over-the-counter and has similar properties

Source for the similarities between chloroquine and quercetin?

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#257
post #133

So I’m not seeing mention of this anywhere else chloroquine is being talked about. Chloroquine used to be taken daily in many of the tropical Britain colonies suffering from malaria. chloroquine in the form of quinine is where the gin and tonic drink came from. Quinine mixed with carbonated water was drunk as a prophylactic. The quinine tasted so terrible it had to be cut with something to make it tolerable - gin! Th…

> As a cheap, safe bet it’s not unreasonable to start having a g&t each day along with a zinc pill. Make that a zinc lozenge , though. Zinc works by coating the esophagus, and killing the virus on contact there. Zinc pills that you simply swallow don't work at all.

[deleted]

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#258
post #133

So I’m not seeing mention of this anywhere else chloroquine is being talked about. Chloroquine used to be taken daily in many of the tropical Britain colonies suffering from malaria. chloroquine in the form of quinine is where the gin and tonic drink came from. Quinine mixed with carbonated water was drunk as a prophylactic. The quinine tasted so terrible it had to be cut with something to make it tolerable - gin! Th…

> As a cheap, safe bet it’s not unreasonable to start having a g&t each day along with a zinc pill. Make that a zinc lozenge , though. Zinc works by coating the esophagus, and killing the virus on contact there. Zinc pills that you simply swallow don't work at all.

Zinc supplements taste nasty and cause a burning sensation on damaged tissue. Zinc lozenges (e.g., Zicam cold-eze) have much lower dose of Zn++ and have sugar added. It is unclear exactly how much zinc in in Zicam. It is far lower than what is in most OTC zinc supplements.

I recommend the nasty zinc supplements: they're cheap, pack a lot of zinc and you'll know when you feel them work. One bottle of 100 tablets 50 mg Zinc gluconate costs for $7 should last you through years of pandemics. In contrast a package of 25 Zicam sugary zinc lozenges costs $15.

I usually split or even quarter a 50 mg zinc tablet - they're that bitter. Don't take too much b/c they may dull sense of smell. Some people claim to have lost their sense of smell due to zinc overdosing. I usually don't take zinc but for this pandemic I've committed to an occasional nasty disgusting fragment of a zinc tablet each day.

Best is to lie down on your back and allow the zinc lozenge or zinc pill to dissolve in your mouth slowly so you can coat the epithelial cells in the mouth, throat and nose. You could gargle with the zinc and then swallow it.

In any case, swallow the zinc b/c that will allow it to be absorbed by the stomach and intestines and then move to your bloodstream, where it can deactivate some virus (more below).

But new virus production occurs inside each cell in the cytoplasm, and little zinc normally passes through the cellular membrane.

Chloroquine and other quinine compounds apparently "punch holes" in the cellular membrane and allow Zn++ ions to flood through. Once inside the cytoplasm Zn++ halts viral replication.

Tonic water has very low levels of chloroquine/quinine but it is by no means established that the full 500 mg chloroquin/day dose used for malaria is necessary to stop covid-19. Probably less, perhaps even far less, will create enough ionic "gateways" to move Zn++ through the cells' membranes. But, in any case, this requires adequate zinc as Zn++ in your system.

And the Zn++ on your throat will inactivate most viruses that land in your throat, nose and mouth anyway.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#259
post #41

I've seen chloroquine come up a ton and am hopeful for the efficacy of its use in treatment of COVID-19. It's surreal to be observing the global impact of a novel pandemic, and anything that can save lives or blunt the propagation of the virus feels like a gasp of hope. Of course, chloroquine is not a vaccine, it's not a tool to contain the spread of SARS-CoV-2. We need massive and rapid propagation of testing, and m…

But if chloroquin , with or without zinc, halts viral replication as is proposed

" Chloroquine Is a Zinc Ionophore"

https://www.ncbi.nlm.nih.gov/pubmed/25271834

then it _is_ a tool to contain the spread of SARS-CoV-2 b/c it could also be used prophylactically. i.e., the virus can't replicate in the human cell if the cell already has adequate chloroquin + Zn++ present.

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