Live data from Hacker News

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)

ncbi.nlm.nih.gov

21–23 of 23 posts

Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)

#21
post #6

Anyone with actual knowledge know the state of ACE2 inhibitor and chloroquinine efficacy?

No actual knowledge, but apparently the way Coronaviruses kill your lung cells is by inhibiting their ACE2 receptors, so I doubt taking an additional ACE2 inhibitor would be helpful. C.f.: https://www.stephenharrodbuhner.com/wp-content/uploads/2020/...

Coronavirus destroys the ACE2 receptors as well as well kills the cell.

If you have an ACE2 receptor inhibitors that do not damage the cell it would be quite helpful as they would prevent infection while only temporarily disrupting RAS function.

P.S. stephen harrod buhner is a herbal “medicine” quack so stop posting his nonsense.

I swear contagion should win an Oscar for being dead on the money. Preferably a new category “called it”.

Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)

#22
post #6

Earlier quoted context omitted.

No actual knowledge, but apparently the way Coronaviruses kill your lung cells is by inhibiting their ACE2 receptors, so I doubt taking an additional ACE2 inhibitor would be helpful. C.f.: https://www.stephenharrodbuhner.com/wp-content/uploads/2020/...

Coronavirus destroys the ACE2 receptors as well as well kills the cell. If you have an ACE2 receptor inhibitors that do not damage the cell it would be quite helpful as they would prevent infection while only temporarily disrupting RAS function. P.S. stephen harrod buhner is a herbal “medicine” quack so stop posting his nonsense. I swear contagion should win an Oscar for being dead on the money. Preferably a new cate…

> P.S. stephen harrod buhner is a herbal “medicine” quack so stop posting his nonsense.

Do you have any criticisms of the actual PDF I posted?

Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)

#23

Earlier quoted context omitted.

Coronavirus destroys the ACE2 receptors as well as well kills the cell. If you have an ACE2 receptor inhibitors that do not damage the cell it would be quite helpful as they would prevent infection while only temporarily disrupting RAS function. P.S. stephen harrod buhner is a herbal “medicine” quack so stop posting his nonsense. I swear contagion should win an Oscar for being dead on the money. Preferably a new cate…

> P.S. stephen harrod buhner is a herbal “medicine” quack so stop posting his nonsense. Do you have any criticisms of the actual PDF I posted?

You mean besides the fact that they recommend taking herbs and hoping for the best?

Ironically they recommend ACE2 inhibitors which was one of the primary treatment protocols explored with SARD just form unproven herbal “remedies”.

Post reply on HN