Anyone with actual knowledge know the state of ACE2 inhibitor and chloroquinine efficacy?
Well, the Chinese claim chloroquine is effective in domestic RCT. And since China seems to be light years ahead of CDC/FDA, I'm inclined to believe them.
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
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Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#12Anyone with actual knowledge know the state of ACE2 inhibitor and chloroquinine efficacy?
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#13Anyone with actual knowledge know the state of ACE2 inhibitor and chloroquinine efficacy?
"Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies."
What China did there was they spent huge effort to find possible cures from existing drugs in the entire drug database known to mankind, herbal medicines included.
Safety is kind of validated because it's known drug, the dosage might be different but I am sure some were tested with high dosages too.
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#14Anyone with actual knowledge know the state of ACE2 inhibitor and chloroquinine efficacy?
No actual knowledge, but apparently the way Coronaviruses kill your lung cells is by inhibiting their ACE2 receptors, so I doubt taking an additional ACE2 inhibitor would be helpful. C.f.: https://www.stephenharrodbuhner.com/wp-content/uploads/2020/...
Second part of this video is a helpful explanation of how it attacks.
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#15I would have liked (2018) in the title since it's an article from March 2018. At first glance I interpreted that it was directly tested on the current strain.
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#16I would have liked (2018) in the title since it's an article from March 2018. At first glance I interpreted that it was directly tested on the current strain.
I flagged it because I was happy and thought it's the result of the new trial that supposed to come out in a few weeks. I'm disappointed now :(
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#17Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#18I would have liked (2018) in the title since it's an article from March 2018. At first glance I interpreted that it was directly tested on the current strain.
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#19Earlier quoted context omitted.
Well, the Chinese claim chloroquine is effective in domestic RCT. And since China seems to be light years ahead of CDC/FDA, I'm inclined to believe them.
What a dangerous line of thinking you have.
Why should I distrust an Chinese RCT over an RCT the US hasn't even bothered to consider?
Re: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) (2018)
#20Earlier quoted context omitted.
I flagged it because I was happy and thought it's the result of the new trial that supposed to come out in a few weeks. I'm disappointed now :(
OOC, what does flagging do exactly? What does a flag mean here?