Chloroquine phosphate has shown apparent efficacy in treating Covid-19
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Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#2Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#3I've been watching the videos in this youtube channel today, where the last couple of videos have talked about this finding : https://youtu.be/U7F1cnWup9M and https://youtu.be/vE4_LsftNKM
Basically the goal is to allow zinc to get into a cell, it needs a helper to get inside the cell (a Zinc Ionophore). Apparently based on the 2nd video, Hydroxychloroquine is even more effective than Chloroquine. It's really important to note however that these are lab based findings, not from studies on patients.
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#4https://factcheck.afp.com/chloroquine-has-not-been-approved-...
Some enterprising Nigerian has apparently been trying to illegally sell it in the UK at least.
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#5For a slightly more balanced perspective, try this paper: https://www.sciencedirect.com/science/article/pii/S016635422...:
Highlights from that paper (all of which look quite reasonable to me, as a non-expert):
• In vitro data suggest that chloroquine inhibits SARS Cov-2 replication.
• In past research, chloroquine has shown in vitro activity against many different viruses, but no benefit in animal models.
• Chloroquine has been proposed several times for the treatment of acute viral diseases in humans without success.
• The outcomes of some current clinical trials of chloroquine in China have been announced, without access to the data.
• Peer review of the results and an independent assessment of the potential benefit for patients are essential.
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#6For a slightly more balanced perspective, try this paper: https://www.sciencedirect.com/science/article/pii/S016635422... : Highlights from that paper (all of which look quite reasonable to me, as a non-expert): • In vitro data suggest that chloroquine inhibits SARS Cov-2 replication. • In past research, chloroquine has shown in vitro activity against many different viruses, but no benefit in animal models. • Chloroq…
>The outcomes of some current clinical trials of chloroquine in China have been announced, without access to the data.
This seems to be the link to the details of clinical trials in China that are made available
http://www.chictr.org.cn/searchproj.aspx?title=氯喹&officialna...
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#7Honestly this is a perfect example of a time when laws are excessively restrictive. I should have the right to purchase this drug and use it as a last resort in the case that I or my family are infected.
It's not fair to responsible people who are capable of researching safety and dosages to have to pay for the ignorance of others. Especially when this drug is OTC in most of the world. You don't need a medical degree to safely administer most drugs - and you should have the right to take that risk, even if that means ignorant people getting hurt or dying.
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#8For a slightly more balanced perspective, try this paper: https://www.sciencedirect.com/science/article/pii/S016635422... : Highlights from that paper (all of which look quite reasonable to me, as a non-expert): • In vitro data suggest that chloroquine inhibits SARS Cov-2 replication. • In past research, chloroquine has shown in vitro activity against many different viruses, but no benefit in animal models. • Chloroq…
How is it balanced when the counterpoints themselves are just speculations?
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#9[deleted]
Re: Chloroquine phosphate has shown apparent efficacy in treating Covid-19
#10Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Re…
Yes, that's the abstract