Can someone translate this from tactical to English?
"We've got bupkis".
P3: Pandemic Prevention Platform (2017)
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Re: P3: Pandemic Prevention Platform (2017)
#22It all sounds good but I’m not sure if they could do all that in 60 days with human trials needed to test actual efficiency, toxicity, etc. If you are talking about just a candidate drug yeah, that is possible with today’s tech.
They are 2 for 2 already: >The teams have proven they can meet this ambitious timeline in previous trials using the influenza and Zika viruses.
What happened to 3? This virus
Re: P3: Pandemic Prevention Platform (2017)
#23More detail: https://www.defenseone.com/technology/2020/03/us-military-sc... https://www.popularmechanics.com/military/research/a31405691...
Thank you. Since the publication isn't even dated, it could have been written 30 years ago because it's only buzzword soup. Example: > A principal benefit of the nucleic-acid-based approach to limiting the spread of infection is that genetic constructs introduced into the body would process quickly and not integrate into an individual’s genome. Similarly, the antibodies produced in response to treatment would only be…
Sure, the understanding of what to do we had 30 years ago, but the technical challenges were only recently overcome (Science, then Engineering).
Re: P3: Pandemic Prevention Platform (2017)
#24These briefs don't mention it by name, but this technology seems like "DNA Vaccination" that has been in research for some years. https://en.wikipedia.org/wiki/DNA_vaccination
This isn't vaccination, it's coding and expression of the antibody(s) your body would take weeks/months to make from a vaccination that neutralize the pathogenic target from dosing. It's a stop-gap to prevent infection, but does not offer memory response from resident B-cells/plasma cells.
Re: P3: Pandemic Prevention Platform (2017)
#25Can someone translate this from tactical to English?
"We've got bupkis".
We had decades of smart thinking about this, and forsaw the need 3 years ago based on Ebola. Things are now in trial, so if it's 2020 and you're reading this, sorry, the funding is already committed. Better luck next time. Keep your ear to ground and move faster.
Re: P3: Pandemic Prevention Platform (2017)
#26I wonder who on earth will use chlorine in ww1 or bio... it kills both sides.
Just crazy thinking but is this why they are military research. If you can protect from icbm ...
It is horrible. If you let this onto china, they can invent a wuhan virus, with these tool to protect their solider or potentially ransom The world then release not accidentally but deliberately the virus. Just like they got the patent for the anti-viral drug.
Crazy.
Re: P3: Pandemic Prevention Platform (2017)
#27I don't remember hearing anything about the US military being involved in the recent Ebola outbreak, so is this an existing program or a proposal?
US Marines and Army troops were sent to Liberia during the Ebola outbreak.
https://news.usni.org/2014/10/08/100-marines-liberia-thursda...
Re: P3: Pandemic Prevention Platform (2017)
#28More detail: https://www.defenseone.com/technology/2020/03/us-military-sc... https://www.popularmechanics.com/military/research/a31405691...
Thank you. Since the publication isn't even dated, it could have been written 30 years ago because it's only buzzword soup. Example: > A principal benefit of the nucleic-acid-based approach to limiting the spread of infection is that genetic constructs introduced into the body would process quickly and not integrate into an individual’s genome. Similarly, the antibodies produced in response to treatment would only be…
I think what they are describing is literally called a vaccine.
Re: P3: Pandemic Prevention Platform (2017)
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Re: P3: Pandemic Prevention Platform (2017)
#30I don't remember hearing anything about the US military being involved in the recent Ebola outbreak, so is this an existing program or a proposal?
The military (Fort Detrick and USAMRIID in particular) is a huge part of the virology community. Civilian academics in the field interact with it regularly.