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Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

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Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#131

Post by riku_iki »

stjohnswarts wrote: post #103
riku_iki wrote: post #70

Earlier quoted context omitted.

The biggest issue with ketogenic diets is elevated level of cholesterol, which is generally considered harmful, though there are different views on this topic.

I have always had very normal cholesterol numbers. It gives you a better HDL (good chol) to LDL(bad chol, maybe) ratio and is good for lowering triglycerides (definitely bad chol) which is the worst type of cholesterol. Your information is not true and is a common misconception about the diet.

In my observation there are many contradicting studies about LDL and keto, for example this study's results show significant increase in LDL while on keto: https://www.ncbi.nlm.nih.gov/pubmed/31067015

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#132

Post by cageface »

wirrbel wrote: post #105
riku_iki wrote: post #70

Earlier quoted context omitted.

The biggest issue with ketogenic diets is elevated level of cholesterol, which is generally considered harmful, though there are different views on this topic.

The causality of elevated cholesterol and coronary heart disease isn't entirely proven. What we see in studies is mostly correlations. Cholesterol-reducing drugs have been shown to not lower the risks associated with high cholesterol levels, so I do think this is an area where we may not have the complete picture yet. Dr. Jason Fung has a few interesting figures in his book, citing studies where the consumption of eg…

People who are born with unusually low cholesterol levels also seem to be essentially immune to heart attacks. I don't have the link to the study handy since I'm on my phone.

Be careful what evidence you accept on this question. There are billion dollar industries doing their best to confuse the issue.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#133

Post by text70 »

pc86 wrote: post #65
text70 wrote: post #61

Earlier quoted context omitted.

I am having trouble agreeing with the statement that "...your body will convert the protein to glucose..." Could you elaborate on that logic?

This[0] is a good starting point. Dietary protein can readily be converted to glucose in the body and either stored as fat or used as energy. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636610/

Ah, ok. I think I figured out where my confusion was at regarding the catabolic pathways from both gluconeogenic and ketogenic amino acids. The correction looks something like [Keto-Acids[Ketone bodies]]

While most catabolic products are categorically and chemically ketones, the list of ketone bodies mostly falls within the list of Keto-Acids. All of which can get passed to TCA at some point, which in turn can feed into gluconeogenesis if the reaction pathway energy is favorable.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#134

Post by cageface »

wirrbel wrote: post #111
throwaway_tech wrote: post #52

Earlier quoted context omitted.

It is possible, I have done it myself eating a lot of eggs and fatty red meat. Also, in my case I was also already in ketosis for an extended period of time, meaning my microbiome and cells were primed for ketosis. That said I have also done carnivore and also not been in ketosis, which I think is probably the norm for most people on carnivore because the protein/fat ratios aren't right. The commonality in ketosis ca…

Meat also raises insulin, much less than carbs, but on a carnivore diet I can imagine this to happen. The keto diet with ratios has been designed as a diet for epileptics, so in a ratio that maintains both body weight in a healthy range and induces ketosis and avoids ceizures (note: 1920s medicine or something). So the high fat content kind of is there to actually give you the energy so that you don't loose weight. O…

Meat raises insulin levels significantly. A steak spikes your insulin harder than a plate of spaghetti.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#135

Post by lanternslight »

dhimes wrote: post #90
ypcx wrote: post #76

Earlier quoted context omitted.

In my personal case I'm not really able to enter and maintain good ketosis levels without also fasting intermittently. Intermittent fasting is key to enabling me to lower my caloric input because of the momentum of the fasting phase carried over into the eating phase, e.g. smaller stomach and more effective metabolism. I currently fast about 12 hours per day (including the sleep phase), which doesn't sound like much…

As an N of one, I present my situation: Since mid-January this year I have been fasting intemittently. I have zero calories before 5PM, and I am usually in bed by 10. I exercise most weeks between 4 and six days, but only two or so are "vigorous" for me. My workouts are mid-day. When I eat, I eat normally for me, which is lower carb and higher protein, but not (knowingly) keto or anything. I have lost about 10 pounds…

Reduce your protein and increase your fat intake. Ideally, 80-90% of your calories should be from fat. Excess protein is converted to glucose.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#136

Post by tokamak-teapot »

riku_iki wrote: post #74
cgh wrote: post #66

Earlier quoted context omitted.

Drop all starchy carbs and replace with meat, eggs and vegetables. It’s not rocket science.

You need to add some butter, oil and heavy cream, or chances are you are not in ketosis: 80% of you calories intake should come from fat to guarantee ketosis.

This is a popular misconception. Please check the [1] keto FAQ on Reddit.

[1] https://www.reddit.com/r/keto/wiki/faq#wiki_how_do_i_start_a...

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#137

Post by Enginerrrd »

skizm wrote: post #102
throwaway_tech wrote: post #17

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

How does working out at a high intensity work when in a state of Ketosis? I lift weights and/or do HIIT 5x per week and occasionally add running on top of that. I've always been weary of going low carb or trying a keto diet because I feel like I just won't have the energy to continue my training regimen at its current intensity. The typical advice is to eat your allocated carbs 1-2 hours prior to your workout, howeve…

It seems people have pretty individualized responses to this. In general, the research shows decreases in performance except for endurance events. Personally, I found my recovery was great on keto. Better than normal even. I was doing a strength cycle so my weights were increasing at the time and I was getting stronger. I actually felt better in the gym, and I lift pretty heavy. A lot of the aches and pains in my joints seemed to go away. Downsides: my gut felt weird, and you have work hard at getting adequate fiber and stuff. Also, it's hard to eat socially.

I was eating a higher protein diet than usually considered keto, but urinalysis confirmed ketosis.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#138

Post by cageface »

nscalf wrote: post #45
collyw wrote: post #30

Earlier quoted context omitted.

Is this definite and scientific consensus? Nutrition research seems to change as often as JavaScript framework of the month. I saw one Ted talk that essentially said "everyone is different and no rules apply to everyone".

The real issue is that nutrition science is bad and everyone has a book. Maybe 1 in 20 studies don't have obvious confounding factors that cause us to have no real base facts, but we can find a lot of correlation. Unfortunately, this is kind of the nature of the beast, nutrition science isn't bad because nutrition scientists are bad, but rather because it's so complicated it's tough to have very clean data. Demonizin…

The government may have been advocating low fat diets but of course people don't follow nutrition advice. If you look at what people were actually eating in the time you describe they started eating more of everything. Consumption of chicken and cheese in particular exploded.

Sugar consumption has actually been in decline for years now and obesity keeps climbing. Yes sugar is bad for you but blaming modern health problems just on sugar is not accurate.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#139

Post by lanternslight »

whiddershins wrote: post #115
throwaway_tech wrote: post #17

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

I would like a citation on the protein to glucose claim. My understanding is the body would much rather run on ketones than go down that path.

No citation, but If you think about it it makes sense: is you have no fat left, and aren't ingesting enough calories, your body would rather burn muscle than organs.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#140

Post by lanternslight »

simonebrunozzi wrote: post #104
throwaway_tech wrote: post #17

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

Any specific reading on how to get into ketosis that you would suggest? Something that you find scientifically sound?

Join the CSK group on FB.
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