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Wuhan seafood market may not be source of novel virus spreading globally

sciencemag.org

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Re: Wuhan seafood market may not be source of novel virus spreading globally

#2
There is a recently opened P4 biolab in Wuhan within miles of the seafood market in question, with researchers who have recently been working with and publishing on the topic of Corona viruses, including research on human transmission. Not to be sensationalist, and personally I think the title is alarmist, but are a number of suspicious elements to this story that are worth examining:

https://medium.com/@siradrianbond/coronavirus-2019-ncov-part...

Re: Wuhan seafood market may not be source of novel virus spreading globally

#3

There is a recently opened P4 biolab in Wuhan within miles of the seafood market in question, with researchers who have recently been working with and publishing on the topic of Corona viruses, including research on human transmission. Not to be sensationalist, and personally I think the title is alarmist, but are a number of suspicious elements to this story that are worth examining: https://medium.com/@siradrianbon…

Medium account was suspended...

Re: Wuhan seafood market may not be source of novel virus spreading globally

#4
post #3

There is a recently opened P4 biolab in Wuhan within miles of the seafood market in question, with researchers who have recently been working with and publishing on the topic of Corona viruses, including research on human transmission. Not to be sensationalist, and personally I think the title is alarmist, but are a number of suspicious elements to this story that are worth examining: https://medium.com/@siradrianbon…

Medium account was suspended...

It’s up for me.

Re: Wuhan seafood market may not be source of novel virus spreading globally

#5
"Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag"

https://biorxiv-cache.s3-us-west-2.amazonaws.com/2020.01.30....

> [ABSTRACT] We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.

Re: Wuhan seafood market may not be source of novel virus spreading globally

#6
post #3

There is a recently opened P4 biolab in Wuhan within miles of the seafood market in question, with researchers who have recently been working with and publishing on the topic of Corona viruses, including research on human transmission. Not to be sensationalist, and personally I think the title is alarmist, but are a number of suspicious elements to this story that are worth examining: https://medium.com/@siradrianbon…

Medium account was suspended...

https://outline.com/YThtcD

Re: Wuhan seafood market may not be source of novel virus spreading globally

#7
post #3

Earlier quoted context omitted.

Medium account was suspended...

It’s up for me.

Must still be a cache somewhere for you. When I try to view it, it says "This account is under investigation or was found in violation of the Medium Rules."

Re: Wuhan seafood market may not be source of novel virus spreading globally

#8
post #3

There is a recently opened P4 biolab in Wuhan within miles of the seafood market in question, with researchers who have recently been working with and publishing on the topic of Corona viruses, including research on human transmission. Not to be sensationalist, and personally I think the title is alarmist, but are a number of suspicious elements to this story that are worth examining: https://medium.com/@siradrianbon…

Medium account was suspended...

https://archive.is/kMl5m

Re: Wuhan seafood market may not be source of novel virus spreading globally

#9

"Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag" https://biorxiv-cache.s3-us-west-2.amazonaws.com/2020.01.30.... > [ABSTRACT] We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in ot…

FWIW, https://old.reddit.com/user/BurrShotFirst1804 is claiming that this (preprint, unreviewed) paper is very misleading, speaking as (supposedly) someone highly familiar with at least one of these HIV proteins. Not sure what to make of either the paper itself or this response to it.

Re: Wuhan seafood market may not be source of novel virus spreading globally

#10

"Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag" https://biorxiv-cache.s3-us-west-2.amazonaws.com/2020.01.30.... > [ABSTRACT] We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in ot…

Can someone translate this?
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