If you are trying to build a NAS or similar then my suggestion is go with shucked WD EasyStore externals, you need to either use molex to sata power to bypass the 2.2v issue or tape the pin but they are WD Whites inside and work very well from my experience. I just keep waiting for the 14TB's to fall a little further so I can replace one of my 5TB parity drives with that so I can grow my array.
You mean the 3.3v issue. In most cases, you can also just clip the 3.3v wire that goes to the sata power connectors from your power supply. It's orange, you won't be missing out by not having it anymore, and it's easy to clip with wire cutters. You should put a dab of electrical tape on the cut ends, but a clean cut isn't likely to short on anything. Consider it updating your power supply to the latest SATA spec.
Some people do have sata enclosures that provide 3.3v, and they may need tape on their drives, or something more drastic.