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New coronavirus can spread between humans, but started in a wildlife market

nationalgeographic.com

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Re: New coronavirus can spread between humans, but started in a wildlife market

#111

Post by golemiprague »

EndXA wrote: post #23

Key quote from the article: > “If we were to shut the wildlife markets, a lot of these outbreaks would be a thing of the past,” says Ian Lipkin, director of Columbia University’s Center for Infection and Immunity, whose lab worked with Chinese officials to develop early diagnostic tests for SARS. > That’s because both SARS and the new outbreak are zoonotic, meaning these diseases started in animals before spreading t…

Isn't it like saying "if we were to shut up gay sexual relationships"? Because the main way for distribution of HIV is via gay anal sex, so if we close the market why not ban gay sexual relationships? Maybe that's why the bible forbidden eating of those type of animals and gay relationships, at least they were consistent

Re: New coronavirus can spread between humans, but started in a wildlife market

#112

Post by treis »

TeMPOraL wrote: post #45
onlyrealcuzzo wrote: post #40

Earlier quoted context omitted.

The odds of this naturally occurring in China are probably close to 1 in 4. And the odds of it happening in Wuhan are probably close to 3%. The odds of the Chinese government making a super virus based on Coronavirus seem smaller than that, and the odds of it escaping the laboratory might be decent, but when you combine them, it's pretty slim. If this were some super strain of Smallpox, that would make a more convinc…

> The odds of the Chinese government making a super virus based on Coronavirus seem smaller than that, and the odds of it escaping the laboratory might be decent, but when you combine them, it's pretty slim. I don't think anyone is arguing that this is an outbreak of an unusually dangerous virus. It's just an unexpected outbreak of a new flu-levels-of-dangerous virus, and it happened suspiciously close to a BSL-4 fac…

>I don't think anyone is arguing that this is an outbreak of an unusually dangerous virus.

It's not unusually dangerous. Viruses kill lots and lots of people every year. This one doesn't seem to be more dangerous than any other. It's just new.

Re: New coronavirus can spread between humans, but started in a wildlife market

#113

Post by lol768 »

throwawaylolx wrote: post #74

How common is for SARS coronaviruses to share the same envelope proteins? I downloaded 200 CoV envelope proteins from NCBI, and I couldn't find any pair of identical proteins. As someone unfamiliar with virology, I'm curious if there are any explanations for how come the protein envelope of 2019-nCoV[1] is the same as the protein envelope described by the Institute of Military Medicine Nanjing Command 2 years ago in…

Some additional information: this paper cites the unpublished paper you mention ("Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats"): https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

With regard to ZC45, which your paper discusses, it states:

> The genome of our virus strains are phylogenetically closest to the bat SARS-related coronaviruses first found in the Chinese horseshoe bats, Rhinolophus sinicus, captured in Zhoushan, Zhejiang province, China, between 2015 and 2017. The full virus genome had about an 89% nucleotide identity with bat-SL-CoVZC45, which makes it a new species. Moreover, the Spike protein of our virus has an 84% nucleotide identity with the bat-SL-CoVZC45 coronavirus and an 78% nucleotide identity with the human SARS coronavirus.

Doesn't answer your question as to how common this is, but provides some additional context on the extent of similarities.

Re: New coronavirus can spread between humans, but started in a wildlife market

#114

Post by jeffdavis »

svara wrote: post #106
DevX101 wrote: post #30

I'm bordering on conspiracy theory territory here, but I'd also like an real investigation into whether the virus actually originated from the Wuhan Biosafety Laboratory. It's the only level 4 (BSL-4 highest rating) lab in all of China designated to handle the most dangerous pathogens. And it's located 20 miles from the reported epicenter in the wildlife market. It was first opened two years ago and at the time multi…

This seems rather unlikely. We have the genome sequence of the Wuhan seafood market coronavirus, and it's consistent with it being a so far unknown relative of the SARS virus and other coronaviruses (see my other comment where I have posted links to the sequence alignments). So did the Wuhan BSL-4 lab virologists discover a new relative of the SARS virus, study it in their lab, didn't publish it, then accidentally se…

Does that contradict the idea that a similar virus was found and then modifed in the lab?

Re: New coronavirus can spread between humans, but started in a wildlife market

#115

Post by Supermancho »

TeMPOraL wrote: post #45
onlyrealcuzzo wrote: post #40

Earlier quoted context omitted.

The odds of this naturally occurring in China are probably close to 1 in 4. And the odds of it happening in Wuhan are probably close to 3%. The odds of the Chinese government making a super virus based on Coronavirus seem smaller than that, and the odds of it escaping the laboratory might be decent, but when you combine them, it's pretty slim. If this were some super strain of Smallpox, that would make a more convinc…

> The odds of the Chinese government making a super virus based on Coronavirus seem smaller than that, and the odds of it escaping the laboratory might be decent, but when you combine them, it's pretty slim. I don't think anyone is arguing that this is an outbreak of an unusually dangerous virus. It's just an unexpected outbreak of a new flu-levels-of-dangerous virus, and it happened suspiciously close to a BSL-4 fac…

> it happened suspiciously close to a BSL-4 facility

This facility is more likely placed because of opportunity for study in a high risk area. The consumption of random "sweet jungle meat" at the local markets likely has a legacy notoriety for such outbreaks.

Re: New coronavirus can spread between humans, but started in a wildlife market

#116

Post by echelon »

chrisco255 wrote: post #49
sdiw wrote: post #21

From what I've read it came from bats. Most probably bats being eaten.[1] Bats have been the source of at least 4 pandemics. It's interesting to note that current coronavirus spreading in China and the SARS outbreak of 2003 have two things in common: Both are from the coronavirus family, and both were passed from animals to humans in a wet market.[2] I tried to put together a page for coronavirus in China here where…

I've heard the bat eating theory, but the virus is airborne and infects the lungs. So it seems that eating a bat probably didn't cause this.

Method of transmission does not stop bats from being a reservoir for the virus.

It was already capable of making the species jump (else it wouldn't), and could have further adapted to using other transmission routes once it got into humans.

The long incubation time makes me think it takes awhile for the virus to get a foothold.

Re: New coronavirus can spread between humans, but started in a wildlife market

#117

Post by skylabmelody »

DevX101 wrote: post #30

I'm bordering on conspiracy theory territory here, but I'd also like an real investigation into whether the virus actually originated from the Wuhan Biosafety Laboratory. It's the only level 4 (BSL-4 highest rating) lab in all of China designated to handle the most dangerous pathogens. And it's located 20 miles from the reported epicenter in the wildlife market. It was first opened two years ago and at the time multi…

It has already happened multiple times in the past, four times in Beijing alone: https://thebulletin.org/2014/03/threatened-pandemics-and-lab...

Re: New coronavirus can spread between humans, but started in a wildlife market

#119

Post by Zod666 »

leeshire wrote: post #118

I don't understand why people eat monkey or bats? if they have all these virus or diseases in them. It's 2020 we have more food in the world than we did years ago no need to eat a bat just grab an apple.

We're talking about a place where this is common practice.

https://m.youtube.com/watch?v=zrv78nG9R04&feature=youtu.be

Re: New coronavirus can spread between humans, but started in a wildlife market

#120

Post by [deleted] »

Zod666 wrote: post #119
leeshire wrote: post #118

I don't understand why people eat monkey or bats? if they have all these virus or diseases in them. It's 2020 we have more food in the world than we did years ago no need to eat a bat just grab an apple.

We're talking about a place where this is common practice. https://m.youtube.com/watch?v=zrv78nG9R04&feature=youtu.be

[deleted]
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