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Scientists identify pathways that extend nematode worm lifespan fivefold

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Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#101
post #61

Earlier quoted context omitted.

By the same token, there are animals who have the „live for 400 years“ problem solved so there must be sth left on the table yes? Other animals have the „regenerate this body part“ problem solved, same.

Some have the never get cancer solved (I read that about chickens... but I can't remember where)

Elephants get much less cancer than their body size suggests. Lots of articles but here's one: https://www.sciencealert.com/elephant-cancer-resistance-nonc...

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#102
post #18
post #15

Earlier quoted context omitted.

That's not interesting, because the Bible is a work of fiction, and thus not relevant to any discussions of scientific merit.

Its just an observation, fiction or not. i remember this fact from the bible and its funny how in this article they talk about 400-500years human lifespan.

Could you explain the exact connection, though? I don't understand what's funny about it. It'd be like a book written 100 years ago saying "humans can fly", and then in 2200 someone invents a cheap portable jetpack. If you lived in 2200, would you say "it's funny" that that old book mentioned flying and look, here we are, flying?

Plenty of other old texts depict long-lived humans as well. It's probably been a fantasy among humans for many thousands of years.

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#103
Wait - did we actually start by extending the lifespans of our parasites???

https://en.wikipedia.org/wiki/Nematode

"The roughly 2,271 genera are placed in 256 families. The many parasitic forms include pathogens in most plants and animals. A third of the genera occur as parasites of vertebrates; about 35 nematode species occur in humans."

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#105

Wait - did we actually start by extending the lifespans of our parasites??? https://en.wikipedia.org/wiki/Nematode "The roughly 2,271 genera are placed in 256 families. The many parasitic forms include pathogens in most plants and animals. A third of the genera occur as parasites of vertebrates; about 35 nematode species occur in humans."

When we started living longer, and in greater numbers, so did they. Only fair that this trend continues...

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#106
post #66

Dang, my retirement savings will have to last much longer than I had expected.

While stated in what I interpret is a joking way, it is a very real concern. As the average life expectancy increases we either have to plan for a longer period of non-productivity (in the private sector) or work longer. A blend of the two seems to be what is occurring, but over my life time I have seen my expected retirement age continue to push slightly further away.

I expect it to be non-existent for a huge chunk of the economy. Well paid programmer types can FIRE, but honestly they can keep working until they can't sit upright or think clearly. Folks like welders have their eyes and knees go in their 40s.

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#107

Earlier quoted context omitted.

I do all of those things, but I am finding the NMN to be quite costly. I take almost the same amount as Dr. Sinclair, which means going through a bottle of pills every three to five days. I really hope someone makes a less expensive version soon. I do feel the difference and can probably attribute it to higher ATP production. I have no idea if it's helping my cardio vascular system.

How many milligrams of NMN do you take each day?

Approx 800mg. The pill size varies with vendor so sometimes a little more and sometimes a little less.

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#108

Earlier quoted context omitted.

How many milligrams of NMN do you take each day?

Approx 800mg. The pill size varies with vendor so sometimes a little more and sometimes a little less.

How are you getting that much without bankrupting yourself? It's extremely expensive, even in bulk powder form.

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#109

Earlier quoted context omitted.

Approx 800mg. The pill size varies with vendor so sometimes a little more and sometimes a little less.

How are you getting that much without bankrupting yourself? It's extremely expensive, even in bulk powder form.

I second that. I have to spend a lot to get 800mg/day. That's why I would love to see more companies make it and the price come down. I fully understand the molecule is a little more complex than its precursor, but maybe if more people made it, then the price would come down? /shrug

Re: Scientists identify pathways that extend nematode worm lifespan fivefold

#110

Earlier quoted context omitted.

How are you getting that much without bankrupting yourself? It's extremely expensive, even in bulk powder form.

I second that. I have to spend a lot to get 800mg/day. That's why I would love to see more companies make it and the price come down. I fully understand the molecule is a little more complex than its precursor, but maybe if more people made it, then the price would come down? /shrug

Are you taking metformin/etc as well?
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