I do wonder if every generation picks slightly higher hanging fruits in science will there come a time when a single human lifetime won't be enough to digest even the most specialised domain of science in order to build upon it
But as we all know (especially those of us who have refactored many systems), every once in a while you find a new way of looking at a thing that makes it all much simpler. A geometric way to look at an algebraic thing, or vice versa. Or a unifying structure to combine disparate pieces. Or just a "wow that was dumb" undoing of unnecessary complexity. It makes further progress easier.
I could imagine that, as the boundaries of science get more complex, there will be more scientists working on making the rest of it less complex. Meanwhile, maybe we get smarter and live longer. The calculations involved with many areas of modern science have already outpaced what we can do by hand, but we invented computers, so I can take the mean of a zillion numbers without much effort and spend my time elsewhere.
And in med school, apparently they say "half of what we teach you will be false, but we don't know which half." As science progresses, you don't just add, you prune too.