101–110 of 132 posts
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It always fascinates me how powerful the placebo effect is. If people believe false health claims they seem to become true health claims.
Something I read recently is that anti depressants are less effective since their initial release, mostly because of placebo wearing off.
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US is not the only country in the world, and there have been studies linking teenage use to psychosis and schizophrenia
What’s the link? Perhaps teenagers with schizophrenia are predisposed to using marijuana. For instance, 80%+ of schizophrenics smoke cigarettes. Do cigarettes cause psychosis and schizophrenia, or do schizophrenics seek out nicotine due to their schizophrenia? It’s not that simple.
(one of these reasons was dietary: MAOIs have bad interactions with the amino acid "Tyramine", found in aged foods. However, Tyramine content in food has dropped dramatically since the 70s, and this is no longer a significant concern)
The full paper is paywalled ($24).
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There's lots of pro-cannabis and pro-LSD comments everywhere. My cynical view is that the "power" wants us all sedated, and it's investing its media to promote the "new" batch of drugs to get another generation hooked up. I do think that there are probably quite beneficial uses of drugs, but probably not in a ludic way as most people prefer to use them.
Certainly one of the things that gives me the creeps are the CBD quiosques freaking everywhere selling what amounts to CBD weed, CBD lotions, CBD potions, CBD whatever; I've seen them in airports, in tourist locations and in shopping malls. Mostly completely unpatronized, with a sullen presumably CBD anesthetized employee manning the desk. Just for the rent and employees we're talking something like a hundred million…
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There's lots of pro-cannabis and pro-LSD comments everywhere. My cynical view is that the "power" wants us all sedated, and it's investing its media to promote the "new" batch of drugs to get another generation hooked up. I do think that there are probably quite beneficial uses of drugs, but probably not in a ludic way as most people prefer to use them.
I think at least with regards to HN, it's that the average user is, just being honest, wealthy and from a very privileged background without too much lifetime difficulty. There's a disproportionate number of people here who can and did walk into Silicon Valley and said something along the lines of "give me 10 million dollars and I'll make a phone app", then have the free time and comfortable fall back to write a fail…
How is this relevant? Many of us who support decriminalization do so because of the impact it has had on less fortunate communities. Those who are privileged should be using their privilege to help those communities by promoting decriminalization.
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US is not the only country in the world, and there have been studies linking teenage use to psychosis and schizophrenia
What’s the link? Perhaps teenagers with schizophrenia are predisposed to using marijuana. For instance, 80%+ of schizophrenics smoke cigarettes. Do cigarettes cause psychosis and schizophrenia, or do schizophrenics seek out nicotine due to their schizophrenia? It’s not that simple.
I’d guess there’s orders of magnitude more smokers than schizophrenics, making it seem unlikely smoking is a primary driver, though I’m sure there’s more to it than that.
I hear 80%+ of all perpetrators of sexual violence engage often with porn, but suspect that if porn drove sexual violence, its rates wouldn’t be decreasing. Most heart attack sufferers drink water within days of their cardiac event. All lottery winners have lottery tickets...
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Unfortunately we don't have enough research to establish much of anything beyond the current FDA approved usage. However, that usage is 600mg/day for an average person (10mg/kg/day). So the claim of 600mg being the "absolute minimum dose" is absurd. Plenty of studies have occurred at levels as low as 25mg/day and shown effects. The quality of those studies isn't great, but there aren't any good quality studies on CBD…
> I can feel as little as 1mg (I'm hypersensitive to the stuff). What gives you the confidence that this isn't the placebo affect at work?
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> I can feel as little as 1mg (I'm hypersensitive to the stuff). What gives you the confidence that this isn't the placebo affect at work?
Nothing with any scientific rigor. Of course I, like I'm sure everyone else, believe I have a decent "placebo detector" and to that end CBD isn't behaving like a placebo for me. But I'll try to add a little more strength to my claim for CBD not being a placebo at the original comment's supposed "low doses". I've used it in balm form to treat physical pain. I use it at ~50mg topical doses (again much lower than 600mg)…
This statement invalidates everything that follows after. Do multiple blind trials with a control substance at varying threshold doses, then you can say whether these "feelings" are from the drug itself.
Placebo creates a very real, measurable physiological effect, so relying on your subjective experience is more than "scientifically unrigorous", it's actually flawed reasoning. And citing a lack of evidence doesn't mean you can suddenly use your own anecdotal data as evidence.
Recently, a friend came to me with a list of all the health benefits that are attributed to cannabis. I sent him back a list of all the health benefits attributed to good old ginger - and they matched almost one to one. Health claims concerning cannabis are usually just for those who want to consume a drug and feel better about themselves.
Is your friend called "straw man", by any chance? And hey, people feeling better about themselves is not such a bad thing, especially when the world is so full of judgemental pricks who can't seem to be able to mind their own business or keep their religious superstitions to themselves.
Recently, a friend came to me with a list of all the health benefits that are attributed to cannabis. I sent him back a list of all the health benefits attributed to good old ginger - and they matched almost one to one. Health claims concerning cannabis are usually just for those who want to consume a drug and feel better about themselves.