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Vice Ventures is investing in taboo industries that other funds won’t touch

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Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#131

Earlier quoted context omitted.

Science says that there is a distinction between the colloquial definition of "addicted" and the technical definition of a physiological / psychological addiction. Many people will also say that a delicious food, an entertaining game, or an enjoyable TV show is "addictive", but these do not actually constitute addictions either.

Sure, but science doesn’t say that, per se, because science is about quantitative measurement. We have no machine that can measure addiction. People with scientific backgrounds hypothesize all the time, and they have machines that can make brain scan images, but we aren’t very close to being able to measure addiction on a numerical scale. The best we have is listening to people, maybe analogous to how we listen to pe…

I actually just happened to be hanging out downtown and found myself at a convention for people devoted to answering just that question!

DeltaFOSB is a gene transcription factor and is the precursor for the development of all forms of what is clinically called "addiction". However what the other commentators suggested [food is not addictive] is not actually true, it has a measurable affect here. In fact, Delta-FOSB can be and often is used as a biomarker of addiction in patients who are already deceased (and can have their brains broken open).

Now, as to the question of addictiveness, nobody mentioned anything about pornography there, but I did hear an interesting anecdote about the raw power that certain addictions have that clearly isn't present in pornography; Delta FOS-B accumulates in the ventral tagamental area and nucleus accumbens, two central regions of the brain, and many drugs have the action of creating floods of FOS-B precursors there, for example, this effect is so strong in heroin addicts, that they nearly always throw up upon recent re-exposure (sometimes newer Methamphetamine addicts as well) where the mechanism here is the flood of FOSB, which an outer region (she had mentioned but I have already forgotten which) interprets as "poisoning". So while it may be true that pornography is "addicting" - when is the last time you saw someone throw up when they looked at pornography (modulo ordinary "disgust").

What was doubly interesting was that she said the change in dopamine regulation (meaning the introduction of new dopamine-like substances + the change in the rate that your body "reuptakes" dopamine) in the most powerful addictions -- benzodiazapines and opiates, aren't actually that high, and compared with drugs like methamphetamine and cocaine aren't much different from marijuana.

It's this secondary affect that creates these changes in reasoning and reward structure with these drugs (she also mentioned that both have "withdrawal", which while technically unrelated to addiction is extremely painful and sometimes life-threatening).

However, to be fair, it was repeatedly stressed that the "secondary" affect was more than just Delta-FOSB. There were changes in signaling, new kinds of peptides that unaddicted people can't produce (???), something about phosphoration of camp ("new notes on camp") and bunch of change to "Dendritic Spiny Structures".

Among the living, questions like "drug-use reinstatement likelihood", "place conditioning preference" (the more addictive the drug, the more you want to use it in a safe, known place), increase in use over time, etc. are how this stuff is generally measured with reasonable economics.

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#132
post #34

Earlier quoted context omitted.

If it's sex or drugs or any sort of addiction, the user is victim. With weapons, other people are the victim.

Unless you use a weapon for self defense.

Self-defense doesn't exist according to HN. The SFPD should be good enough for anybody, which means all private guns are just murder waiting to happen.

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#133

Earlier quoted context omitted.

That's really not true, you can't run a giant public company and start breaking laws because you think 'the current executive branch won't care'.

CounterExamples: (And before anyone gets triggered about me talking about politics, please notice that the examples below are referring to both parties in the same light) 1. Selling marijuana is still illegal federally but there are hundreds of companies selling it out in the open in states where it is legal. Neither Republican or Democratic Presidents seem to have much interest in prosecuting them. Yes I know The fo…

Your first example is a contradiction between state law and federal law. Large public companies seemed to stay out of this business for that reason.

Your second example was also not something large public companies were doing consistently and I don't think that has changed with a different administration.

"Uber" is not any sort of statement or reasoning in support of what you are saying.

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#135

Earlier quoted context omitted.

CounterExamples: (And before anyone gets triggered about me talking about politics, please notice that the examples below are referring to both parties in the same light) 1. Selling marijuana is still illegal federally but there are hundreds of companies selling it out in the open in states where it is legal. Neither Republican or Democratic Presidents seem to have much interest in prosecuting them. Yes I know The fo…

Your first example is a contradiction between state law and federal law. Large public companies seemed to stay out of this business for that reason. Your second example was also not something large public companies were doing consistently and I don't think that has changed with a different administration. "Uber" is not any sort of statement or reasoning in support of what you are saying.

Uber is a national company whose business model was predicated on breaking local laws.

The Koch Brothers run multiple national companies and had one of their companies recently raided for employing illegal immigrants.

https://www.chicagotribune.com/business/ct-biz-ice-raids-koc...

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#136

Earlier quoted context omitted.

Your first example is a contradiction between state law and federal law. Large public companies seemed to stay out of this business for that reason. Your second example was also not something large public companies were doing consistently and I don't think that has changed with a different administration. "Uber" is not any sort of statement or reasoning in support of what you are saying.

Uber is a national company whose business model was predicated on breaking local laws. The Koch Brothers run multiple national companies and had one of their companies recently raided for employing illegal immigrants. https://www.chicagotribune.com/business/ct-biz-ice-raids-koc...

> Uber is a national company whose business model was predicated on breaking local laws.

Nope

> The Koch Brothers run multiple national companies and had one of their companies recently raided for employing illegal immigrants.

Are you implying they did this because the previous administration 'did not care' ? That's a large assumption.

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#137

Earlier quoted context omitted.

Uber is a national company whose business model was predicated on breaking local laws. The Koch Brothers run multiple national companies and had one of their companies recently raided for employing illegal immigrants. https://www.chicagotribune.com/business/ct-biz-ice-raids-koc...

> Uber is a national company whose business model was predicated on breaking local laws. Nope > The Koch Brothers run multiple national companies and had one of their companies recently raided for employing illegal immigrants. Are you implying they did this because the previous administration 'did not care' ? That's a large assumption.

So Uber wasn’t breaking local taxi laws for years?

Everyone knows that farmers and companies employing low skill labor have been employing illegal immigrants for decades. Other presidents both Republican and Democrats have looked the other way because both sets of employers would not be able to find enough cheap labor otherwise. No one wants to harm the farm belt because of their outsized electoral college influence.

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#138

Earlier quoted context omitted.

> Uber is a national company whose business model was predicated on breaking local laws. Nope > The Koch Brothers run multiple national companies and had one of their companies recently raided for employing illegal immigrants. Are you implying they did this because the previous administration 'did not care' ? That's a large assumption.

So Uber wasn’t breaking local taxi laws for years? Everyone knows that farmers and companies employing low skill labor have been employing illegal immigrants for decades. Other presidents both Republican and Democrats have looked the other way because both sets of employers would not be able to find enough cheap labor otherwise. No one wants to harm the farm belt because of their outsized electoral college influence.

I don't think anything Uber did related to selectively ignoring laws when a new administration took office.

How is any of this about large companies not caring about laws because of a new president?

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#139

Earlier quoted context omitted.

So Uber wasn’t breaking local taxi laws for years? Everyone knows that farmers and companies employing low skill labor have been employing illegal immigrants for decades. Other presidents both Republican and Democrats have looked the other way because both sets of employers would not be able to find enough cheap labor otherwise. No one wants to harm the farm belt because of their outsized electoral college influence.

I don't think anything Uber did related to selectively ignoring laws when a new administration took office. How is any of this about large companies not caring about laws because of a new president?

Well seeing that your question doesn’t have anything to do with the thread...

My post:

“ It’s not about the regulations, it’s about whether the executive branch chooses to enforce them and how much.”

And the response to:

“ That's really not true, you can't run a giant public company and start breaking laws because you think 'the current executive branch won't care'.”

What does it have to do with “changing” the executive branch?

The “executive branch” is not just at the federal level. It’s also at the state and the local level where the president/governor/mayor has a lot of influence on what gets enforced.

Re: Vice Ventures is investing in taboo industries that other funds won’t touch

#140

Earlier quoted context omitted.

I don't think anything Uber did related to selectively ignoring laws when a new administration took office. How is any of this about large companies not caring about laws because of a new president?

Well seeing that your question doesn’t have anything to do with the thread... My post: “ It’s not about the regulations, it’s about whether the executive branch chooses to enforce them and how much.” And the response to: “ That's really not true, you can't run a giant public company and start breaking laws because you think 'the current executive branch won't care'.” What does it have to do with “changing” the execut…

Ah, so now it's about state governments somehow and for some reason. It seems like every time you bring something hyperbolic and generally untrue that you can't back up, you shift to something else.
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