A woman with a rare genetic mutation that has protected her from dementia
1–10 of 42 posts
Re: A woman with a rare genetic mutation that has protected her from dementia
#2Nytimes did a piece in 2017 about a similar situation [1] about studying the Tsimané [2] and the Tsimané Project [3]; it's a different slant on Alzheimer's but, with such a complex issue, we need to federate and examine all such views.
[1]https://www.nytimes.com/2017/07/14/opinion/sunday/alzheimers... [2] https://en.wikipedia.org/wiki/Tsiman%C3%A9 [3] http://tsimane.anth.ucsb.edu/index.html
Re: A woman with a rare genetic mutation that has protected her from dementia
#3Very clickbaity title. Suggest a change to: "Rare genetic mutation protects this woman from dementia", or something more descriptive.
Re: A woman with a rare genetic mutation that has protected her from dementia
#4Yet another exception to an incurable disease. This happens all the time.
Re: A woman with a rare genetic mutation that has protected her from dementia
#5It could actually be an additional regulatory de novo mutation or epigenetic mutation that is preventing the expression of that mutated gene.
Despite what people below say, understanding the pathways involved is significant because drugs can be made to replicate the same biological effect to block the disease. This is what biopharma looks for.
Re: A woman with a rare genetic mutation that has protected her from dementia
#6Nytimes did a piece in 2017 about a similar situation [1] about studying the Tsimané [2] and the Tsimané Project [3]; it's a different slant on Alzheimer's but, with such a complex issue, we need to federate and examine all such views. [1] https://www.nytimes.com/2017/07/14/opinion/sunday/alzheimers... [2] https://en.wikipedia.org/wiki/Tsiman%C3%A9 [3] http://tsimane.anth.ucsb.edu/index.html
Re: A woman with a rare genetic mutation that has protected her from dementia
#7Not paywalled - "Colombian woman’s genes offer new clues to staving off Alzheimer’s" - https://www.sciencemag.org/news/2019/11/colombian-woman-s-ge...
Re: A woman with a rare genetic mutation that has protected her from dementia
#8Re: A woman with a rare genetic mutation that has protected her from dementia
#9Very clickbaity title. Suggest a change to: "Rare genetic mutation protects this woman from dementia", or something more descriptive.
We've switched to that phrase from the subtitle.
Re: A woman with a rare genetic mutation that has protected her from dementia
#10How do they know? Have they been shooting her with a dementia gun?