In case anyone was confused by the article's description, here's the Wikipedia: "SABRE (Synergetic Air Breathing Rocket Engine) is a concept under development by Reaction Engines Limited for a hypersonic precooled hybrid air-breathing rocket engine. The engine is being designed to achieve single-stage-to-orbit capability, propelling the proposed Skylon spaceplane to low Earth orbit. SABRE is an evolution of Alan Bond…
the benchmark of today - SpaceX - separates the first stage at Mach6-8 at 65-80km height. Thus, the SpaceX second stage has less delta-v to add and don't have to carry all that weight - the SABRE would naturally be bigger than the 2nd stage for the same payload. The economical space related case of HOTOL/SABRE single-stage-to-orbit pretty much disappeared for a foreseeable future when SpaceX started to recover the 1st stage. That not to say about suborbital flights SF-Shanghai though. Or even "just" hypersonic as SABRE tech seems to successfully deal with one of the major/key obstacles for it (and that is huge, i'm in no way trying to dismiss their work). And one can see how SABRE can be used in some cases as a convenient 1st stage, i.e. by being able to launch from any big airport instead of only specially designed spaceports (such a 1st stage would probably be better than that https://en.wikipedia.org/wiki/Pegasus_(rocket)#Carrier_aircr...).