Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Artificial blood developed for patients of any blood type, researchers say

asahi.com

Post reply on HN
Print view View original

101–109 of 109 posts

Re: Artificial blood developed for patients of any blood type, researchers say

#101

Post by Mountain_Skies »

Blakestr wrote: post #79
M2Ys4U wrote: post #56

Earlier quoted context omitted.

I would have thought that getting blood into trauma patients in the field would be the main application for this? Once back in a hospital setting they could switch to using real blood.

Paramedic here - two main areas of concern regarding blood in the prehospital/emergency setting - 1 - Volume - You need enough fluid in a closed system to maintain pressure to push that fluid. 2. Oxygen carrying capacity - Oxygen binds with red blood cells which then deliver it to every cell in your body. Right now the prehospital setting can more or less manage #1, we have been for a century with Normal Saline. Ther…

Does #1 mean that a person with high blood pressure is more able to survive blood loss than a person with standard blood pressure?

Re: Artificial blood developed for patients of any blood type, researchers say

#102

Post by ldoughty »

Mountain_Skies wrote: post #101
Blakestr wrote: post #79

Earlier quoted context omitted.

Paramedic here - two main areas of concern regarding blood in the prehospital/emergency setting - 1 - Volume - You need enough fluid in a closed system to maintain pressure to push that fluid. 2. Oxygen carrying capacity - Oxygen binds with red blood cells which then deliver it to every cell in your body. Right now the prehospital setting can more or less manage #1, we have been for a century with Normal Saline. Ther…

Does #1 mean that a person with high blood pressure is more able to survive blood loss than a person with standard blood pressure?

Not a medic/doctor, but I would assume higher pressure would result in pushing blood out of your system faster. This probably offsets gains

Re: Artificial blood developed for patients of any blood type, researchers say

#103

Post by ldoughty »

toomuchtodo wrote: post #21
njsubedi wrote: post #16

Earlier quoted context omitted.

Probably not. The "rejuvenating effects" come from the body of young donors, so I don't think the artificial blood contains most of the components that human blood contains.

Citations for this subthread. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836258/ (Young Blood Rejuvenates Old Bodies: A Call for Reflection when Moving from Mice to Men) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770779/ (Young plasma reverses age‐dependent alterations in hepatic function through the restoration of autophagy) (Money quote: "Recent studies showing the therapeutic effect of young blood on aging‐a…

Thank you. I would love to read these sources when I'm able to!

Re: Artificial blood developed for patients of any blood type, researchers say

#104

Post by Scapeghost »

BillinghamJ wrote: post #8

This is really interesting. I wonder whether it truly is compatible with every single person, e.g. even RH-null etc? I also wonder whether religious groups who don't accept blood would potentially accept this.

> I also wonder whether religious groups who don't accept blood would potentially accept this.

Religion is a disease on its own.

If it actively hinders your survival and well-being, what else would you classify it as? It belongs with depression, schizophrenia and all the other psychological disorders.

This is from someone from a religious country.

Re: Artificial blood developed for patients of any blood type, researchers say

#106

Post by Marsymars »

wbl wrote: post #32
platz wrote: post #29

Historically, there have been many efforts in the past to make artificial blood and IIRC they didn't turn out well for the patients. It's a bit like the the body with vitamins. At first they thought vitamins were all you needed - then they started discovering micro-nutrients. Blood is pretty complex - does this include just the highest-order bits of blood, or does it include everything that blood has?

If I'm bleeding out and the blood bank is dry I'm not going to be so picky. A few weeks later I'll have made my own to replace it.

If you're bleeding out and compatible blood isn't immediately available, we already have several volume expanders that can be used.

Re: Artificial blood developed for patients of any blood type, researchers say

#107

Post by sundvor »

givinguflac wrote: post #4
toomuchtodo wrote: post #2

Can a domain expert comment if this does away with the whole blood donation/testing/storage/logistics system we currently have?

Once in full production, potentially. But currently it's only been tested on rabbits. This could change the face of medicine if successful.

If significantly fewer people were encouraged to donate, I wonder what that would do to the pool of bone marrow donors.

At least in Australia you're encouraged to sign up for this as you donate, which makes it very easy for them to run the needed tests.

Re: Artificial blood developed for patients of any blood type, researchers say

#108

Post by AlexanderNull »

BillinghamJ wrote: post #8

This is really interesting. I wonder whether it truly is compatible with every single person, e.g. even RH-null etc? I also wonder whether religious groups who don't accept blood would potentially accept this.

Most of those groups reject all parts of blood transfusion. This "artificial" blood only replaces the platelets and red blood cells so would still require plasma and white blood cells for a balanced breakfast.

Re: Artificial blood developed for patients of any blood type, researchers say

#109

Post by afarrell »

stevenpetryk wrote: post #94
afarrell wrote: post #24

Earlier quoted context omitted.

> Does this mean it is possible that some portion of blood collected from "blood donation programs" goes waste? Yes. For any system which regularly collects some resource and distributes it somewhere else, some amount of that resource goes to waste. It is impossible to absolutely eliminate this. Therefore, all resource-distribution systems expect some level of waste.

This reads like you're unsubtly telling OP "your question is dumb" while also not answering the real (intriguing, nuanced) underlying question.

I don't intend to tell OP that their question is dumb. But I am definitely completely missing the underlying question if there is one.
Post reply on HN