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Lab-made primordial soup yields RNA bases

nature.com

91–100 of 134 posts

Re: Lab-made primordial soup yields RNA bases

#91
post #17

> Carell, an organic chemist, and his collaborators have now demonstrated a chemical pathway that — in principle — could have made A, U, C and G (adenine, uracil, cytosine and guanine, respectively) from basic ingredients such as water and nitrogen under conditions that would have been plausible on the early Earth. The reactions produce so much of these nucleobases that, millennium after millennium, they could have a…

First you have some shell script, then you have static code (dna)?

Re: Lab-made primordial soup yields RNA bases

#92
It may not be necessary for complex organic molecules to assemble out of nothing in a finely tuned primordial soup. Two recent studies to illustrate this:

1. Simple chemical droplets can divide and multiply in the right conditions: https://arxiv.org/pdf/1603.01571v1.pdf

2. “Evolution” from that simple beginning may be enough according to the theory of dynamic kinetic stability: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843823/

Re: Lab-made primordial soup yields RNA bases

#93
post #42
post #17

> Carell, an organic chemist, and his collaborators have now demonstrated a chemical pathway that — in principle — could have made A, U, C and G (adenine, uracil, cytosine and guanine, respectively) from basic ingredients such as water and nitrogen under conditions that would have been plausible on the early Earth. The reactions produce so much of these nucleobases that, millennium after millennium, they could have a…

There's a multiverse theory that there are many possible or existing universes with different physical constants, affecting everything from chemistry to orbital mechanics, and the reason we are having this conversation is because this universe was conducive to the formation of highly organized lifeforms capable of abstract thought. In this line of reasoning "Why this set of constants" doesn't matter, because only the…

None of what you said remotely answers their question.

Re: Lab-made primordial soup yields RNA bases

#94

Earlier quoted context omitted.

The anthropic principle doesn't depend on a multiverse.

Not on a multiverse directly, but I think there is merit to @hinkley's claim. Say there's a one trillionth chance that life forms on an earth-like planet. There are likely trillions of earth-like planets, so chances are good (given the assumptions) that life forms on (at least) one of those planets. People on that planet (Earth) will marvel that life was created and search for reasons that seem plausible and likely f…

One of the things we're trying to figure out is how likely life is to form on an Earth-like planet. Of course it happened here, but we have no idea how common it is.

If we do the chemistry and figure out the mechanism and it looks like it happens all the time, then that tells us one more term in the Drake equation and gives us a reason to go check out the exoplanets.

Re: Lab-made primordial soup yields RNA bases

#95

Earlier quoted context omitted.

What are the alternative theories that are more plausible, in your opinion?

DNA teleportation.., the recent discussion on HN about the hydrophobic effect of DNA basically proves it is true... naysayers be damned! https://en.m.wikipedia.org/wiki/DNA_teleportation https://news.ycombinator.com/item?id=21051949 https://en.m.wikipedia.org/wiki/Water_cluster http://www1.lsbu.ac.uk/water/magnetic_electric_effects.html

[deleted]

Re: Lab-made primordial soup yields RNA bases

#96

A while ago I read somewhere that the odds of life creating itself via basic chemical pathways are so miniscule, that there must be quite a few instances of mechanical clocks creating itself by rocks beating together over the aeons in the universe before the first dna based organism appeared. Might be very wrong but still a beautiful picture.

I tend to think statements like that say more about the knowledge and passions of the writer than about the laws of the universe.

The fundamental point underlying the Nature article is that we don't actually know "the odds of life creating itself via basic chemical pathways". What we do know is that life appeared on Earth quite soon after liquid water.

Re: Lab-made primordial soup yields RNA bases

#97
post #40

Earlier quoted context omitted.

It is great that you've found a way to feel superior to others with your purpose narrative.

Please don't take HN threads further into flamewar, and please don't cross into personal attack. https://news.ycombinator.com/newsguidelines.html

Fair enough

Re: Lab-made primordial soup yields RNA bases

#98
post #84

Earlier quoted context omitted.

No invisible hand is required. Any life form that has reached the cognitive capability to reason about itself will be amazed by the sheer "coincidence" of their habitat. "wow, isn't it amazing that our planet's atmosphere is composed of the very ammonia we need to survive in?" No invisible hand required. Also evolution is "intelligently selective". Surviving and reproducing is a pretty intelligent mechanism. It will…

> Any life form that has reached the cognitive capability to reason about itself will be amazed by the sheer "coincidence" of their habitat. "wow, isn't it amazing that our planet's atmosphere is composed of the very ammonia we need to survive in?" Isn't this a non sequitur? Whether any life form would wonder about its existence (probable or otherwise) has no bearing whatever on whether it evolved or was designed or…

We should not be surprised that the environment we find ourselves in is so seemingly well-suited to the flourishing of life. I believe the grandparent post was saying this as a response to the idea that things are too improbably perfectly-suited for us. Far from being a non-sequitur, it is almost stating a tautology. The environment we find ourselves in is the one that has given rise to us, with our ability to think about these things.

I'm sure there is a Douglas Adams passage that illustrates this but I can't remember it.

Re: Lab-made primordial soup yields RNA bases

#99
post #28
post #17

> Carell, an organic chemist, and his collaborators have now demonstrated a chemical pathway that — in principle — could have made A, U, C and G (adenine, uracil, cytosine and guanine, respectively) from basic ingredients such as water and nitrogen under conditions that would have been plausible on the early Earth. The reactions produce so much of these nucleobases that, millennium after millennium, they could have a…

I agree, but keep in mind abiogenesis is probably one of the tallest orders for chemistry. I'm glad scientists are at least exploring possible explanations, even if it means possibly disproving the mechanisms.

What are the alternatives? Even with panspermia life would have had to begin elsewhere. The universe would have been too hot at the Big Bang to support organic molecules if that theory is true. Even with “intelligent design” the intelligence would have its own heritage and origin. The implications of an alternative to abiogenesis seem outside the realm of scientific inquiry entirely. Is the desire here a coherent, detailed narrative for how we went from hot plasma to RNA?

Re: Lab-made primordial soup yields RNA bases

#100
post #21

Earlier quoted context omitted.

The Neo-Darwinists are downvoting me, no doubt. I don't buy the Christian fairytale, either. In fact, I'm happy to accept that none of us know what the origin of life is. Life is just too complicated to be an accident of random, purposeless matter. Life is also too complex and multi-faceted to be explained by any religion's mythos.

It is great that you've found a way to feel superior to others with your purpose narrative.

So... you flagged me because you think I'm making some supposed statement of superiority?

Also, what "purpose" narrative?

Is contradicting the Neo-Darwinist model of life somehow not allowed?

Does contradicting it make me a closet Christian, in your eyes?

Because I don't see an answer in Neo-Darwinism or any religion.

I'm happy not knowing, just as I'm happy to criticize people who claim to know.

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