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Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

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61–70 of 75 posts

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#62

I thought calcium had a bigger impact on bone density than Vitamin D?

There is no documented positive effect above 300mg/day.

300 milligrams!?!

Current advice is don't take more than 100 micrograms per day.

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#63
post #62

Earlier quoted context omitted.

There is no documented positive effect above 300mg/day.

300 milligrams!?! Current advice is don't take more than 100 micrograms per day.

Calcium, not vitamin D.

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#64
As mentionned by other commenters, the study does not seem to mention K2 and magnesium. When it comes to bone health, my understanding is that D, K2, Mag and Calcium, probably other minerals play a crucial role.

And since K2 is made in the gut, gut health, once again, should be taken into account?

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#65
As with all Vitamin D studies, this one should discuss or acknowledge the differences in intake requirements for people of different ethnic groups. It doesn't, which means that for some of us, the findings balance somewhere between useless and dangerous.

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#66

Earlier quoted context omitted.

I don't think "compared to not taking any at all" is an accurate summary here. Even if you never touch a Vitamin D supplement, many people are already getting an amount comparable to the baseline used in this study from a typical diet, or from sun exposure.

Except, say, for 6-9 months every year if you're vegan and living in cold climates...

2/3 of Americans get the RDA of Vitamin D. Picking a specific outlier case for your control group wouldn't make a lot of sense for a scientific study (not to mention, as others have pointed out in this thread, would be difficult or unethical.) If you are a vegan living in a low-sunlight location, look into supplementation.

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#67

Earlier quoted context omitted.

Except, say, for 6-9 months every year if you're vegan and living in cold climates...

2/3 of Americans get the RDA of Vitamin D. Picking a specific outlier case for your control group wouldn't make a lot of sense for a scientific study (not to mention, as others have pointed out in this thread, would be difficult or unethical.) If you are a vegan living in a low-sunlight location, look into supplementation.

So you're saying 1/3 of Americans don't get the RDA of Vitamin D, yet calling 33% of cases "an outlier"

I'm not vegan and I actually take Vitamin D3 supplements, but wanted to point out the flaw in assuming that everyone is in the same bucket as me.

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#68
post #42
post #31

Being a dialysis patient, I have to deal with a lot of the issues of my kidneys not functioning. There is a complex interplay of vitamin D, PTH (from parathroid), phosphorus, calcium levels and bone loss. So I have to take vitamin D, calcitriol and phosphrous binder and dietary restrictions to balance it all. Going too far one way or the other is not good. Every month I get blood tests for all these things and my dos…

Dialysis sucks. It takes away so many of life’s little pleasures. My best to you, brave person.

The kind of treatment I'm having isn't so bad. Its just the time it sucks up plus the inconvenience of travel. I haven't gone on an out of town vacation is ages because of all the equipment I have to drag along. The best I can pull of is weekend trips and stay-cations.

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#69
post #6

I thought you needed both vitamin D and vitamin K2 - D to mobilize the calcium and K2 to put it into the right place. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613455/

Also... Magnesium!

And... Strontium!

Re: Effect of High-Dose Vitamin D on Volumetric Bone Density and Bone Strength

#70
post #56

Earlier quoted context omitted.

Time to start taking vitamin D

You would probably benefit more from being out in the sun than from taking vitamin D supplements.

Yeah, and possibly die of malignant melanoma. At the same time, no sun exposure is also a risk of melanoma - not sure if due to vitamin D or more possibly - due to the hormetic effect of mild skin DNA damage.
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