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U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

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Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#91

Post by umvi »

dragonwriter wrote: post #77
umvi wrote: post #75

Earlier quoted context omitted.

> Legalizing it will drastically mitigate the ability for minors to get a hold of any I can't tell if you are joking or not (sorry). But I simply don't believe this. Why would legalizing it make it harder for minors to get ahold of it?

> Why would legalizing it make it harder for minors to get ahold of it? Legalizing increases the marginal legal risk (and thus expected cost) of selling to minors (still illegal) vs. selling to everyone else. The same is true of non-sale person-to-person distribution.

Ok, so you are saying given X minor marijuana user, it would be harder for X to obtain marijuana post legalization vs. pre legalization. That I agree with because X's dealer is willing to break the law to sell to minors while convenience store employees are less likely to.

However, the point is moot because legalizing marijuana increases it's overall availability, image, and appeal and thus you'll have more minors using it overall post legalization.

To illustrate my point, it would be like saying "legalizing marijuana makes it 50% harder for minors to buy it!" but leaving off the "(but also legalization would increase the number of minor users by 10000+%)" part.

All it would take is for Juul to make THC pods and suddenly you have a HUGE adolescent user base essentially using marijuana overnight that didn't exist before legalization.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#92

Post by WrtCdEvrydy »

bregma wrote: post #41
hartator wrote: post #16

Earlier quoted context omitted.

Not the OP, but this is not anecdotal. Weed can develop schizophrenia in 4-5% of the population that carries a specific gene. Ref: https://www.drugabuse.gov/publications/research-reports/mari...

Do you really think a publication from a place with a URL 'drugabuse.gov' is going to be a reliable source of unbiased information?

> s going to be a reliable source of unbiased information

Kinda like https://www.ready.gov/ for disasters... yes!

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#93

Post by moate »

superkuh wrote: post #4

These are all reasonable things. Legalizing it will drastically mitigate the ability for minors to get a hold of any just as was done with the much more dangerous and deadly drug, alcohol.

The difficulty with this is that it's still easy enough for joe-random to grow. One of the unique properties of pot vs just about any other recreational drug is how little processing is required to get it to a consumable form.

I never knew anyone making bathtub wine or processing their own heroine in HS, but I knew at least a couple kids who tended a couple pot plants.

Seems like there will always be someone doing this, and minors are always going to have relatively easy access to pot.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#95

Post by dleslie »

neaden wrote: post #27
numakerg wrote: post #5

> Edible marijuana takes time to absorb and to produce its effects, increasing the risk of unintentional overdose No citation for this. Do they mean a larger than intended dose or a dose that results in a serious toxic reaction or death? Better source: Median lethal THC dose for a 70kg human estimated to be 4g [0], which is slightly over 1300 full joints (at 3mg per joint) [0]. I won't link them here, but a cursory w…

Larger than intended I would assume. There are plenty of reports of people consuming an edible, not feeling anything for twenty minutes, consuming more, and then having a bad trip.

It's a bad trip insofar as it's _absolutely not_ what you expect, if it's your first time having so much edibles; even if you've inhaled heavily in the past, the manner of the experience changes dramatically when you injest, and varies by strain.

It can be more of an intense psychedelic experience, as opposed to the generally pleasant inebriating experience most are accustomed to with marijuana.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#96

Post by yhoneycomb »

djsumdog wrote: post #6
40acres wrote: post #3

My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis. It was generally terrifying to see him unable to complete thoughts and lose his train of thought. He's fine now but I definitely wouldn't be surprised if you told me those years knocked a couple of points off his IQ. I'm for decriminalization and legalization but at the core we need funding for long term…

> as a result developed schizophrenia I'm sorry about your brother, but I want to point out this is anecdotal. Can cannibals lead to psychosis in people who are prone to it genetically, or are people who start experiencing delusions, bipolar and schizo-effective conditions just likely to escape using alcohol and marijuana? The exact cause/effect conditions here are a big unknown.

It’s not anecdotal. The relative risk for developing schizophrenia for cannabis smokers vs non cannabis smokers is 2.3. This means that you are 2.3 times more likely to develop schizophrenia if you smoke cannabis.

Your post annoys me because it might actually lead people astray. Please try not to talk about things you know little to nothing about.

Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988731/

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#98

Post by habosa »

Reading the comments here is a bit disappointing. There are a lot of legalization advocates seeming to take the position that because weed is mostly fine for most people it's always fine for everyone. It's not.

Anyone here who has a friend who smoked too much when they were young (and we all have that friend) knows that weed, like so many things in life, can be dangerous when you use it too much or when you shouldn't be using it.

Yes it should be legal. Yes adults should be able to buy it. We should also watch, very carefully, how our children use it.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#99

Post by blackhaz »

hartator wrote: post #70
bregma wrote: post #41

Earlier quoted context omitted.

Do you really think a publication from a place with a URL 'drugabuse.gov' is going to be a reliable source of unbiased information?

If you want to nitpick on the source, this is another source with a full publication: > Variation at the rs2494732 locus of the AKT1 gene predicted acute psychotic response to cannabis along with dependence on the drug and baseline schizotypal symptoms. Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872423/

I have magnitude 1.5 on the rs2494732 variation. Love the herb.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#100

Post by wannabcodr »

hartator wrote: post #8
40acres wrote: post #3

My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis. It was generally terrifying to see him unable to complete thoughts and lose his train of thought. He's fine now but I definitely wouldn't be surprised if you told me those years knocked a couple of points off his IQ. I'm for decriminalization and legalization but at the core we need funding for long term…

This. I am all for legalization but it’s not a safe drug. Induced schizophrenia by weed can be a thing if you carry a specific gene.

Marijuana usually begins as a social habit so the pathway to marijuana induced mental issues isn’t going to be so easily tied back to a gene.
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