To my mind, the blockers for Perl 6 adoption in order of importance have been: 1. The name, saddling it with the legacy of Perl. (I say this as someone who really liked working with Perl back in the waning years of the old millennium, and believes that Perl was visionary in pointing the way to the state of modern programming... but also that it had some limitations that have only become more glaring over the years.)…
I would move 4 up to 2. Every time I read an article about how cool Perl 6, I see the clever bits of syntax and think "WTF? I might enjoy playing with that for fun, but no way in hell would I use that for work."
It has some genuinely ambitious features, some things that (as someone who barely dabbles in new languages) that I haven't seen before, or combinations I hadn't seen.
Something novel instead of the umpteenth iteration of "x with a better type system" or "x without that pesky type system".