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Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

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Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#31

Post by Jimpulse »

davinic wrote: post #26
dvt wrote: post #17

I fast, on average, once a week. At least once a month, I try to do an extended fast (2-5 days) to force ketosis. I also do intermittent fasting basically daily (I only eat between 12-8). Been doing this for about 4 years now. Some anecdata: - Fasting > 24 hrs paradoxically gives you an extreme boost of energy and mental focus. I especially love how my olfactory sense is extremely heightened. It's pretty cool and eve…

Can you point to any studies that show the benefits of your vitamin regimen? You point out there are no studies on long term fasting but I am also unable to find the studies on the benefits of vitamins.

examine.com is a pretty good resource on supplements.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#32

Post by 49para »

dvt wrote: post #29
davinic wrote: post #26

Earlier quoted context omitted.

Can you point to any studies that show the benefits of your vitamin regimen? You point out there are no studies on long term fasting but I am also unable to find the studies on the benefits of vitamins.

This is a fair point. In fact, most research seems to point to the fact that vitamins don't really do anything. I just do it out of habit.

Most nutritional studies are worthless.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#33

Post by SwellJoe »

tempsy wrote: post #21
vgoh1 wrote: post #8

Earlier quoted context omitted.

Just as we shouldn't make the assumption that fat people are lazy and gluttonous, we shouldn't make the assumption that skinny people have an eating disorder.

I didn’t say he was sick. I was just recounting my observation. Was literally taken aback by how thin he was. It’s different when you go on record as a public person in multiple interviews talking about extended fasting. People want to emulate influential people, whether it’s actually a healthy or unhealthy behavior for that individual. Also, maybe Steve Jobs would still be alive today if we didn’t have this strange…

Steve Jobs was diagnosed, by his doctor, relatively early, as pancreatic cancer diagnoses go (many people only discover it when they have weeks or months to live, and there are no effective treatment options...five year survival rate for pancreatic cancer is something like 1 in 5). Jobs opted to use alternative treatments rather than treatments that (might) work.

That's a wholly different conversation...nobody diagnosed his condition, or could have helped his outcome, by looking at him and talking about his health on the internet. And, nobody could have diagnosed his condition by looking at him. By the time you have visible symptoms of pancreatic cancer, you've already likely been experiencing pain and other related symptoms, and treatment options are practically nil.

How about we just leave people's health between them and their healthcare providers and optionally their family? It's none of our business, unless they specifically ask us for advice or tell us about it.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#34

Post by lazyguy »

goldemerald wrote: post #25
geoka9 wrote: post #9

Earlier quoted context omitted.

I could think of gallstone disease, but I'm not a doctor.

Specifically, here's the relevant text from the paper: "...extended overnight fasting periods might increase the risk of gallstone disease (Sichieri et al., 1991)"

Par for the course on any sort of diet that has fairly high weight loss.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#35

Post by torben-friis »

dvt wrote: post #17

I fast, on average, once a week. At least once a month, I try to do an extended fast (2-5 days) to force ketosis. I also do intermittent fasting basically daily (I only eat between 12-8). Been doing this for about 4 years now. Some anecdata: - Fasting > 24 hrs paradoxically gives you an extreme boost of energy and mental focus. I especially love how my olfactory sense is extremely heightened. It's pretty cool and eve…

Are you fit? as in, do you lift weights or are active in sports that require strength?

I ask because I wonder about the effects of extended fasts on muscle loss/retention, a big problem cutting weight for some people is that they get rid of some muscle mass along with the calories they wanted to eliminate.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#37

Post by dvt »

49para wrote: post #30
dvt wrote: post #17

I fast, on average, once a week. At least once a month, I try to do an extended fast (2-5 days) to force ketosis. I also do intermittent fasting basically daily (I only eat between 12-8). Been doing this for about 4 years now. Some anecdata: - Fasting > 24 hrs paradoxically gives you an extreme boost of energy and mental focus. I especially love how my olfactory sense is extremely heightened. It's pretty cool and eve…

Why would your body breakdown your organs when you still have plenty of adipose stores ? Do you have a citation for the "starvation mode" ? If it's the 1940's study from MN, that was only when the subjects where well into single digit fat %.

You can see that there was protein turnover just after 10 days in rats: https://www.ncbi.nlm.nih.gov/pubmed/7119891

In healthier rats, protein turnover (cannibalizing muscles / organs) was faster than in obese rats. I had some human studies bookmarked, I'll try to find them again. There were a few ketosis studies that discussed "starvation mode" so maybe try searching for that.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#38

Post by riazrizvi »

tempsy wrote: post #4

I was heading to the gym near the Twitter HQ in SF yesterday and saw Jack Dorsey walk past. He looked extremely thin and borderline sick to me. I think he does more extended fasts over the weekend but it’s a bit unnerving when someone in a position to influence behavior like he is seems to be taking fasting to an extreme.

I think we are a little too comfortable with people generally taking over-eating to an extreme. A 5’ 10” male’s optimal BMI means a body weight between 130lbs and 170lbs. You’d need to be 110lbs to be severely underweight. No-one would bat an eye if they saw a severely overweight 5’10” celebrity weighing 210lbs.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#39

Post by uwuhn »

SwellJoe wrote: post #33
tempsy wrote: post #21

Earlier quoted context omitted.

I didn’t say he was sick. I was just recounting my observation. Was literally taken aback by how thin he was. It’s different when you go on record as a public person in multiple interviews talking about extended fasting. People want to emulate influential people, whether it’s actually a healthy or unhealthy behavior for that individual. Also, maybe Steve Jobs would still be alive today if we didn’t have this strange…

Steve Jobs was diagnosed, by his doctor, relatively early, as pancreatic cancer diagnoses go (many people only discover it when they have weeks or months to live, and there are no effective treatment options...five year survival rate for pancreatic cancer is something like 1 in 5). Jobs opted to use alternative treatments rather than treatments that (might) work. That's a wholly different conversation...nobody diagno…

>How about we just leave people's health between them and their healthcare providers and optionally their family? It's none of our business, unless they specifically ask us for advice or tell us about it.

What about the shareholders?

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#40

Post by throwaway_law »

dvt wrote: post #17

I fast, on average, once a week. At least once a month, I try to do an extended fast (2-5 days) to force ketosis. I also do intermittent fasting basically daily (I only eat between 12-8). Been doing this for about 4 years now. Some anecdata: - Fasting > 24 hrs paradoxically gives you an extreme boost of energy and mental focus. I especially love how my olfactory sense is extremely heightened. It's pretty cool and eve…

- Even on fast days, make sure you take vitamins (I take Fish Oil, Zinc, a Multivitamin and Magnesium)

I have done some fasting recently (water, some water/apple cider vinegar in the morning; coffee, green tea, Ooolong tea), and have a similar vitamin intake (B complex; calcium/D combo; Magnesium; Zinc; Iron; Fish Oil).

During the fasting I don't take the Fish Oil, I haven't read anything about it specifically, but just assumed Fish Oil was fat that would break the fast. Do you have an opinion on that? I'm Guessing the caloric intake (if any, I am not even sure) is not enough to trigger metabolic response, and as a fat wouldn't trigger insulin response.

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