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Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

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161–170 of 233 posts

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#161

Earlier quoted context omitted.

Does that mean that caffeine is a risk too? Doesn't it have similar effects to nicotine? (I drink a loooooot of coffee).

Its bad for blood pressure - I switched to decaf for that reason.

How something raises BP might be important, tho.

/bargaining

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#162

Earlier quoted context omitted.

Smoking is one of the leading risk factors for cardiovascular disease: agreed It starts earlier than a lot of people thought: agreed The primary contributor to smoking's detrimental effects on the cardiovascular system is nicotine: disagree Mind linking to something that shows this? That doesn't agree with the results from the UK study on effects of nicotine versus smoking which puts nicotine's effects at about 5% of…

This is definitely a point which needs more exploring. Seems to me most damage from smoking is all the crap in smoking. The chemical nicotine - by itself - transiently raises BP, feels nice, and that's about it. It's also only a part of the addictiveness of smoking. Probably a small part, as everyone I know who has consumed nicotine in any form has no trouble without it if they vape, but often shows discomfort/restle…

I've been a long-time smoker, and at least for me, nicotine alone does absolutely nothing to alleviate cravings. Gum, patches, lozenges, vaping, etc. do zero to alleviate my craving for a cigarette. I'm not discounting that nicotine is addictive (I'm in no position to say), but there's got to be something else in tobacco that is part of the addiction.

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#163

Earlier quoted context omitted.

This is definitely a point which needs more exploring. Seems to me most damage from smoking is all the crap in smoking. The chemical nicotine - by itself - transiently raises BP, feels nice, and that's about it. It's also only a part of the addictiveness of smoking. Probably a small part, as everyone I know who has consumed nicotine in any form has no trouble without it if they vape, but often shows discomfort/restle…

I've been a long-time smoker, and at least for me, nicotine alone does absolutely nothing to alleviate cravings. Gum, patches, lozenges, vaping, etc. do zero to alleviate my craving for a cigarette. I'm not discounting that nicotine is addictive (I'm in no position to say), but there's got to be something else in tobacco that is part of the addiction.

Nicotine only makes me sick. I've tried gums, vapes, and nicotine salt pouches. I smoke a tobacco pipe when I want to relax.

There are MAOIs in tobacco smoke. I'm not sure that's what makes me feel calm though.

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#164

Earlier quoted context omitted.

This is definitely a point which needs more exploring. Seems to me most damage from smoking is all the crap in smoking. The chemical nicotine - by itself - transiently raises BP, feels nice, and that's about it. It's also only a part of the addictiveness of smoking. Probably a small part, as everyone I know who has consumed nicotine in any form has no trouble without it if they vape, but often shows discomfort/restle…

> The chemical nicotine - by itself - transiently raises BP, feels nice, and that's about it. This is not entirely true. I believe it can put you at risk for cardiac arrhythmia, and the risk goes up steeply the more nicotine you intake to simply cardiac arrest. I believe this is depicted in Thank You For Smoking when the protagonist is covered in nicotine patches and almost dies. It’s entirely possible that was do to…

Nicotine is a poison and will unquestionably kill you at high doses. Same thing with water. Drink enough and you'll die. The relevant question is, what are the negative effects of nicotine at common therapeutic doses?

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#165

One of the frustrating things about ecig studies is that they always use the worst quality hardware and puff really hard on them. The "Epuffer" looks like one of those "cig-a-like" which are notoriously worse than the much more expensive hobbyist mech mods. The cig-a-likes usually don't get enough juice to the heating element so when you're puffing a lot (16 consecutive 3s pulls) you end up burning the wick.

Out of curiosity, are most people that use ecigs going for the expensive mods, or are they going for the more popular brands that are closer in quality to the epuffer?

I don't have any science to back up this, just an opinion. Epuffer is like a conversion product. Once you try it, you likely invest in better equipment. This is what happened to me... Started with a cheap gas station stick, then quickly upgraded to a decent set up. Was able to get my dad to stop smoking by buying him a cheap puffer to test it out. Now he has a full set up.

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#166

Earlier quoted context omitted.

This depends on the relative harm of smoking versus vaping. Uk government estimates risks at 95% less than smoking which means we're still winning health wise by quite a bit.

Vaping appears to have stalled progress towards smoking cessation: https://www.apnews.com/1c899ae55fca41bab3cefcdc37bf6de4 > For decades, the percentage of high school and middle school students who smoked cigarettes had been declining fairly steadily. For the past three years, it has flattened, according to new numbers released Monday. It may also encourage relapses: https://www.reuters.com/article/us-health-ecigare…

From your first link:

“It’s not clear yet what’s going on and it’s best to not jump to any conclusions,” said David Levy, a Georgetown University researcher.

In the UK, teenage smoking is at record lows - just 16% of secondary school children have ever smoked tobacco, down from 19% in 2016. We have not seen a significant rise in youth e-cigarette use. This may have something to do with the 2014 Tobacco Products Directive, which introduced substantial new regulation on both cigarettes and e-cigarettes including restrictions on advertising.

https://www.bbc.co.uk/news/health-49398630

https://en.wikipedia.org/wiki/Tobacco_Products_Directive

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#167
post #58

So I take it, should these results be replicated and validated as scientifically sound, that smoke machines will be banned? Because it's the same kind of aerosol with virtually the same ingredients. I'm also curious - and maybe I missed it; it's a dense paper - that while they mentioned the primary ingredients in "bare" vape liquids, they didn't seem to mention the concentrations of each used in the study? Again, may…

> smoke machines will be banned Do people put smoke machines up to their mouths and inhale it many times a day over many years?

Theater technicians and performers often spend many hours per day for most of their career in close proximity to large smoke machines - essentially huge mains-powered e-cigarettes that use nicotine-free vape juice by the quart.

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#168
post #57

Earlier quoted context omitted.

Juul's creators increased the nicotine because they felt other vapes on the market couldn't compare to the sensations delivered by regular cigarettes. The nicotine salts in Juul pods are a type of nicotine that supposedly feels more like a cigarette when inhaled, as opposed to other vapes that use freebase nicotine. Philip Morris strategy to create confusion is obviously working. Don't buy from big tobacco if your go…

Personally, I couldn't stand the freebase nicotine juice. A hit off some 10mg juice made me feel like I'd just taken a fat haul on a cigar. My mouth started watering, I started twitching a bit and felt like was going to puke, then immediately i started craving a smoke. The nicotine salts don't feel that way, even with the 36mg. It actually takes the cravings away without really giving me that nicotine rush. In a mont…

There is a lot of difference in the quality and composition of freebase juice. The differences between vaporizers is also massive.

I eventually settled on a juice with a coffee caramel flavor that smelled like someone just made a cake.

Go and try several combinations in a store that is specialized. The Juul is Big Tobacco still giving you an old fashion hit of nicotine.

Edit: if you are located in Europe this was my favorite.

https://ea-sigaret.nl/e-liquid-kopen/100-vg-eliquid/vg-e-liq...

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#169

If you believe E-Cigs are harmless, there's an easy experiment you can do for yourself. Go on a run, time yourself. The next day, vape for 30 min and then go on the same run. This is what got me to personally switch away from E-Cigs. Vaping would add an additional 30-sec to 1-min per mile on my runs. I try to only use patches or gum now. Still not great but it's a lot better if you're trying to stay in shape. That be…

when i was in the army, i knew a few guys who swore by smoking before a fitness test. they'd suck down a cigarette just before the run and then pound out a quick 9 minute 1.5mi. it's not something i've bothered to test. i just found it interesting that they must have done something to put that idea in their head.

Re: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function

#170

Earlier quoted context omitted.

I've been a long-time smoker, and at least for me, nicotine alone does absolutely nothing to alleviate cravings. Gum, patches, lozenges, vaping, etc. do zero to alleviate my craving for a cigarette. I'm not discounting that nicotine is addictive (I'm in no position to say), but there's got to be something else in tobacco that is part of the addiction.

Nicotine only makes me sick. I've tried gums, vapes, and nicotine salt pouches. I smoke a tobacco pipe when I want to relax. There are MAOIs in tobacco smoke. I'm not sure that's what makes me feel calm though.

It could be the interaction between the MAOIs and the nicotine. Or more accurately, the MAOIs altering how your body handles nicotine.
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