I'm gonna go out on a limb here and expose my n00bishness, and honestly a lot of that article has my head spinning as I google a lot of terms ;) I've only done web development for a year now and I've seen some cool WebAssembly demos but mostly those are demos of various frameworks (or no framework) reusing random WebAssembly components. It's cool, but I'm missing from a large web application stance how WebAssembly is…
Web assembly is generally an optimization, not an app alternative. Think of it the way you would the C bindings Node.js has. If you've got a compute-heavy code path, writing it in C (or Rust etc) and shipping it as web assembly could be a dramatic perf improvement, but there's not really a substantive benefit to writing your entire app with it.
Amendment: Perhaps it's debatable what "substantive benefit" would be, but writing the whole app in it is a huge benefit if you really want to do that. That is to say, for years people wanted to write Web UI stuff in various languages, this also allows for that.
So while the concrete performance boost may not be meaningful in writing an entire web app in C, Rust, Go, Python or w/e - to the developer happiness the boost may be huge for those devs that want it.