A peculiarity: the "south east" is the area most typically associated with the Conservatives and their voters, who have been in power for the past 9 years and who have driven most of the Brexit rhetoric. The south east is also nearest the Channel Tunnel and ferry ports to the continent, and so their food, drugs, etc. will suffer the least delay, least spoilage, etc. in the case of a "No Deal" Brexit.
You can drive from Dover to almost all of the mainland UK in 8 hours.
The Scottish Highlands will take a bit longer.
It'll be a problem, but I doubt being close to the port will make a difference.