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Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

hopkinsmedicine.org

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Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#61

Post by perseusmandate »

MS90 wrote: post #30

I'll be interested to see how this pans out. I have significant hearing loss in both ears from infections as a baby, and the doctors always said it was because the hairs in my cochlea are dead. I was denied a few opportunities when I was younger due to my hearing, and I still can't hear most higher frequency sounds (whistles, some cymbals, smoke detectors, fire alarms...etc). It would be nice to be able to hear what…

Regrowing literal hair follicles is seemingly more difficult as they are each small, complex organ attached to a muscle (arrector pili) and they become damaged by fibrosis from the inflammatory process of hair loss.

It seems trivial but it is actually a monumentally complex problem to address

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#63

Post by rootbear »

technofiend wrote: post #32
MS90 wrote: post #30

I'll be interested to see how this pans out. I have significant hearing loss in both ears from infections as a baby, and the doctors always said it was because the hairs in my cochlea are dead. I was denied a few opportunities when I was younger due to my hearing, and I still can't hear most higher frequency sounds (whistles, some cymbals, smoke detectors, fire alarms...etc). It would be nice to be able to hear what…

Yours is worse than mine but same root cause and probably exacerbated by power tools and loud music (and loud music at a bar called power tools) later on. There's a huge dip in the middle of my hearing range so I can hear the clink-clink-clink of pint glasses in a pub but people speaking to me over it is a struggle.

> loud music at a bar called power tools

Please tell me this was a gay bar. If it wasn't, it should have been.

I have some upper range hearing loss that's more or less consistent with my age. I also have tinnitus and ADHD, so I'm interested in the comments about how all these things may be interrelated. I definitely struggle to hear conversations in noisy environments and I always assumed it was high frequency hearing loss, but maybe the ADHD is part of it as well.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#64

Post by wrycoder »

MS90 wrote: post #46
technofiend wrote: post #32

Earlier quoted context omitted.

Yours is worse than mine but same root cause and probably exacerbated by power tools and loud music (and loud music at a bar called power tools) later on. There's a huge dip in the middle of my hearing range so I can hear the clink-clink-clink of pint glasses in a pub but people speaking to me over it is a struggle.

Yeah, hearing people over background noise is probably the thing that I struggle with the most. It's been a pretty big social hindrance, especially when I was in college. In crowded social areas like bars and restaurants it's very difficult for me to understand what people are saying. As a result, I ended up being the weird guy just sitting there not saying anything all night because I was unable to carry on a conver…

That was me, also. I found that a pair of Bose Hearphones helped considerably. You can set them to focus 45 deg in front and cancel noise from behind. Basically, you hear the person you are facing. I've been in some incredibly noisy bar environments, and I find younger people are asking me to repeat, though I can make their speech out pretty well.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#65

Post by MS90 »

SubiculumCode wrote: post #55
MS90 wrote: post #46

Earlier quoted context omitted.

Yeah, hearing people over background noise is probably the thing that I struggle with the most. It's been a pretty big social hindrance, especially when I was in college. In crowded social areas like bars and restaurants it's very difficult for me to understand what people are saying. As a result, I ended up being the weird guy just sitting there not saying anything all night because I was unable to carry on a conver…

I am going to venture and say this is not related to the ear apparatus, but in perception processing. I believe this type of deficit has been associated with ADHD, and other neurodevelopmental disorders/variations.

I actually do have ADHD as well, and this was something that the doctors talked about. They told me that my hearing impairment would make it even more difficult to focus paired with the audio processing issues from ADHD.

That said, even in a quiet setting I have trouble understanding someone if I can't see their face/read their lips.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#66

Post by DoreenMichele »

rootbear wrote: post #63
technofiend wrote: post #32

Earlier quoted context omitted.

Yours is worse than mine but same root cause and probably exacerbated by power tools and loud music (and loud music at a bar called power tools) later on. There's a huge dip in the middle of my hearing range so I can hear the clink-clink-clink of pint glasses in a pub but people speaking to me over it is a struggle.

> loud music at a bar called power tools Please tell me this was a gay bar. If it wasn't, it should have been. I have some upper range hearing loss that's more or less consistent with my age. I also have tinnitus and ADHD, so I'm interested in the comments about how all these things may be interrelated. I definitely struggle to hear conversations in noisy environments and I always assumed it was high frequency hearin…

Anecdotally, tinnitus sometimes improves with magnesium supplementation.

It takes time though, on the order of several months, to see results.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#67

Post by bitwize »

sparkzilla wrote: post #43
nosianu wrote: post #34

Earlier quoted context omitted.

So... okay, I did not want to go public at first and emailed privately, but since there are others, and why not: I too had tinnitus for a long time and it all went away after chelation treatment against chronic mercury poisoning from amalgam fillings after being lucky that it was diagnosed (I had to actively search for a rare researcher/university clinic doctor specialist, nearly no chance with normal doctors). See m…

This is very interesting. Can you point me to some articles or further resources?

GP appears to have diagnosed himself with chronic metal poisoning, and doctor-shopped until he found a physician willing to make his self-diagnosis official and prescribe all the oral chelators he convinced himself he needed a priori.

Chronic heavy metal toxicity is a subject rife with quackery and pseudoscience, especially when people start talking about chronic poisoning undetectable by conventional medicine. It's best to be careful whose story you believe. It's a hot button issue for me as a person "on the spectrum" because ill-informed parents subject their kids to Cutler protocol and other fringe chelation therapies under the belief that they're "curing" their kids of autism, and causing more health problems than they fix (chelators are themselves pretty toxic!)

Here are some resources about metal toxicity pseudoscience:

http://www.thinkingautismguide.com/2010/07/autism-and-biomed... (section "The Cutler Protocol")

https://www.quackwatch.org/01QuackeryRelatedTopics/Tests/uri...

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#68

Post by tempestn »

tw1010 wrote: post #33
scarygliders wrote: post #4

I was hoping to read that it might also help people like myself who suffer from tinnitus. Sadly, no. Still, if it can restore hearing to the deaf, this is a good thing.

Would those who regained hearing have tinnitus? I mean, in theory, wouldn't you be able to recover from tinnitus if you made yourself deaf and ate the proteins. Maybe stupid question, but why not?

Some tinnitus is comorbid with hearing loss, but some isn't. If you have hearing loss and tinnitus, it's possible that improving the hearing loss would also reduce or eliminate the tinnitus, as they would appear to be related. If your tinnitus is unrelated to hearing loss though, it seems to me unlikely that giving yourself and then curing hearing loss would have an effect. (Not to rule it out completely, given that the causes of tinnitus are not well understood.)

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#69

Post by loceng »

MS90 wrote: post #30

I'll be interested to see how this pans out. I have significant hearing loss in both ears from infections as a baby, and the doctors always said it was because the hairs in my cochlea are dead. I was denied a few opportunities when I was younger due to my hearing, and I still can't hear most higher frequency sounds (whistles, some cymbals, smoke detectors, fire alarms...etc). It would be nice to be able to hear what…

I honestly don't know if you'd be a candidate, however look into Auditory Integration Training and the idea of hearing imbalances; ear infections are a known cause of creating imbalances, which can lead to hyper- and hypo-sensitivity to sound, and specific frequencies even. There's a book available on Amazon called "Hearing Equals Behaviour: Updated and Expanded" that has original book in it as well. I first did AIT in my early 20s and only after doing it, within a day or two a hypersensitivity to sound I had diminished - which then allowed the resolution/refinement of feeling to return properly to my physical body, touch sensory - to which the hypersensitivity to sound caused a hyposensitivity to touch for me. All kinds of possible and strange ways the brain and mind can break as a way to cope - and especially as a baby your brain development is much more rapid, so disruptions to the normal evolution of different sensory development can of course have more severe or marked symptoms.

I wrote a reply where I suggested people look into Auditory Integration Training for either themselves or their children who they said had certain autistic characteristics. Here's the thread for that: https://news.ycombinator.com/item?id=13657725 - and in particular someone asked to hear about my own experience with it, to which I replied here: https://news.ycombinator.com/item?id=13657973

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#70

Post by technofiend »

rootbear wrote: post #63
technofiend wrote: post #32

Earlier quoted context omitted.

Yours is worse than mine but same root cause and probably exacerbated by power tools and loud music (and loud music at a bar called power tools) later on. There's a huge dip in the middle of my hearing range so I can hear the clink-clink-clink of pint glasses in a pub but people speaking to me over it is a struggle.

> loud music at a bar called power tools Please tell me this was a gay bar. If it wasn't, it should have been. I have some upper range hearing loss that's more or less consistent with my age. I also have tinnitus and ADHD, so I'm interested in the comments about how all these things may be interrelated. I definitely struggle to hear conversations in noisy environments and I always assumed it was high frequency hearin…

>Please tell me this was a gay bar. If it wasn't, it should have been.

Heh. I thought someone might have had that reaction to the name. From the Houston Press:

Power Tools A long-gone cousin of Numbers, Power Tools is still a sacred name (not to mention a powerful memory) among Houston's industrial/goth/EBM crowd, with the downtown subterranean space now occupied by hip-hop/EDM-heavy Kryptonite. Like a few of its kin, Power Tools is practically un-Google-able, but one flyer we did find (again via Ozone City Outrage) offers a powerful whiff: Butthole Surfers. Mid-August. All ages. CHRIS GRAY

But to answer your question, not a gay bar.

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