61–70 of 172 posts
What I am specifically interested in is whether the rate of new infections can be curtailed to below the self-sustaining threshold.
Earlier quoted context omitted.
Actually, it's quite terrifying when you remember that stopping a clinical trial early is a great way to create statistical fraud. https://blogs.sciencemag.org/pipeline/archives/2019/08/08/st... cites an example of a drug whose clinical trial was stopped early due to obviously effective success... only to discover later on that the "obviously effective" was a statistically spurious event, and the drug did not confer…
It seems that if this is the case for this new drug it would be fairly noticable that the death rate jumps back up to 50%
This is awesome that we've seen another horrendous disease go from incurable to curable in my lifetime. While ebola hasn't touched my community like AIDS/HIV has, reading this cracked my RBF and I smiled.
Earlier quoted context omitted.
Unpacking the name totally is even more brutal! "necro" -- "death" "lysis" -- "busting open" "epidermal" -- "skin" "syndrome" -- "no known cause" However, it's a little unclear why TEN is a point of comparison to Ebola, as one is a transmissible disease and one is something that happens to unlucky people typically in response to common small-molecule drugs. I guess TEN sounds like a probable side effect of antiviral…
Is syndrome = "no known cause" a common definition?
So while it is often the case that when a syndrome is initially named its cause is unknown, the two are really referring to different levels of abstraction of a disease. The syndrome is its effects, irrespective of whether we know its cause.
Earlier quoted context omitted.
Unpacking the name totally is even more brutal! "necro" -- "death" "lysis" -- "busting open" "epidermal" -- "skin" "syndrome" -- "no known cause" However, it's a little unclear why TEN is a point of comparison to Ebola, as one is a transmissible disease and one is something that happens to unlucky people typically in response to common small-molecule drugs. I guess TEN sounds like a probable side effect of antiviral…
Is syndrome = "no known cause" a common definition?
Edit: one usage is for a set of commonly concurrent symptoms, possibly with no known cause. Another common usage is a set of concurrent symptoms with multiple known causes (e.g. toxic shock syndrome).
There is no news I enjoy reading more than that a clinical trial had to be ended early because the treatment was so effective that it would be unethical to continue with alternative treatments (or a placebo).
Actually, it's quite terrifying when you remember that stopping a clinical trial early is a great way to create statistical fraud. https://blogs.sciencemag.org/pipeline/archives/2019/08/08/st... cites an example of a drug whose clinical trial was stopped early due to obviously effective success... only to discover later on that the "obviously effective" was a statistically spurious event, and the drug did not confer…
Ebola is now Curable (YC 17)
There is no news I enjoy reading more than that a clinical trial had to be ended early because the treatment was so effective that it would be unethical to continue with alternative treatments (or a placebo).
Actually, it's quite terrifying when you remember that stopping a clinical trial early is a great way to create statistical fraud. https://blogs.sciencemag.org/pipeline/archives/2019/08/08/st... cites an example of a drug whose clinical trial was stopped early due to obviously effective success... only to discover later on that the "obviously effective" was a statistically spurious event, and the drug did not confer…
I really have to apologize if this is not a HN-quality comment, but I initially read this as a startup rebrand announcement. Ebola is now Curable (YC 17)