Consider reading the NixOS documentation if you would like to learn more, because it’s worth it imo, but no, Debian is a different case.
NixOS doesn’t just manage packages, it manages the entire system holistically. You effectively have a single configuration file (or multiple) that configure every package, service, mount, ramdisk, driver, etc. If I delete everything but my home folder, my configuration file can be used to completely recreate the root and all of its configurations. Have a KVM GPU passthrough? That can be expressed. Want to override bashrc or zshrc globally? Yep. Want to setup users, LDAP, Samba, FTP? Same configuration. It goes as far as to make most files read only so that you can’t accidentally change things.
But it goes further with build reproducibility. All builds are hashed with their inputs. Every package specifies the sha256 sum of their sources. If your package builds on one machine, it shall build on another.
But it keeps going further. NixOS eschews normal shared library paths. Binaries always refer to Nix store paths in their runpath, making sure it will only ever load the version of the library it was built to load.
And there is still more. NixOS tracks generations. Any time you rebuild the system to change a config or add a new package to the root, you get a new generation that can be rolled back. The default bootloader lets you choose what generation to boot. So if you mess up your configuration, you very rarely need recovery media.
It may not seem very important, but it pretty much changes how you interact with your OS. If you want to restart from scratch, just make sure you have copies of your home folder and configs and start over. This is great for switching to LVM or deciding to use LUKS, where it may not be easy to do without reformatting.
It does take investment, but if you have multiple machines it becomes amortized. I’m running 3 machines with largely identical setups.