I want to live in a world where everyone is confident in themselves and doesn't care what others think about superficial details outside of character. In the far-far future that may never come, I imagine people exist in a virtual continuum and can change all aspects of their appearance such that they never feel slighted by their perceived place in a fitness gradient they cannot change. Maybe technology is helping us…
On casting Sir Patrick Stewart as Captain Picard: Reporter: "Surely by the 24th century, they would have found a cure for male pattern baldness." Rodenberry: "No, by the 24th century, no one will care." I doubt even a few hundred years will wash out vanity and the worst parts of us, but here's to hoping.
Vain people will definitely still exist, but excess weight or baldness will be probably be a conscious presentation choice and social signal, rather than a marker of genetics or dietary habits.
In this environment it would be incorrect to say "no one will care", but hopefully people will care less and less as they age out of that period of their life in which self expression and fashion choices tend to have gratuitous importance based on our insecurities of youth.