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Animals living alongside humans produce amylase, enzyme that breaks down starch

elifesciences.org

21–30 of 62 posts

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#21
post #2

> This may suggest that our lineage has evolved specific adaptations to digest starch-rich foods, underlining the long and continuing importance of these staples in our diet This reminds me of the interest in keto dieting and the frustrating misunderstanding that carbs are the cause of excess weight, diabetes etc. If that were true, the whole world would be diabetic and obese, since everywhere has a staple carb. It's…

Undoubtedly multi-factorial, but excessive omega-6 fats as a major driver is the most convincing theory I've heard. Interesting reading: https://www.breaknutrition.com/omega-6-fatty-acids-alternati...

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#22
post #2

> This may suggest that our lineage has evolved specific adaptations to digest starch-rich foods, underlining the long and continuing importance of these staples in our diet This reminds me of the interest in keto dieting and the frustrating misunderstanding that carbs are the cause of excess weight, diabetes etc. If that were true, the whole world would be diabetic and obese, since everywhere has a staple carb. It's…

Which scientific journals have you read on the matter to form your opinion? Just curious -- always looking to learn.

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#23
post #12

Although I follow a ketogenic diet and benefit from it I have laughed about the claims that it's somehow aligned with the needs of Paleolithic people. SO I really enjoyed this: "Unlike Neanderthals and Denisovans, who had only two diploid copies, we carry up to 20 copies of the AMY1 gene, which produces salivary amylase. "

Isn't that the opposite of what you believe? Paleolithic people were not genetically adapted to high-starch diets like we are. Ergo, a low-carb diet like keto was more natural for them.

I think the keto / paleo things continued with “...and that’s why we modern humans should emulate a paleo diet.” So, parent poster doesn’t agree with this theory and it’s adherents.

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#24
post #20

Earlier quoted context omitted.

Isn't that the opposite of what you believe? Paleolithic people were not genetically adapted to high-starch diets like we are. Ergo, a low-carb diet like keto was more natural for them.

The "we" in the sentence is homo sapiens. Neanderthals and Denisovans were not the same species as us. > "Unlike Neanderthals and Denisovans, who had only two diploid copies, [homo sapiens] carry up to 20 copies of the AMY1 gene, which produces salivary amylase. "

Doesn't that mean we've evolved to eat a lot of starch so the more natural thing for humans to eat is therefore starch, if you follow this line of reasoning? And therefore, we've "evolved beyond" the keto diet?

FWIW, I do not think this is good reasoning.

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#25
post #6

Earlier quoted context omitted.

There are a few populations without (much) staple carbs, for example the Inuit and the Maasai. But I don't think many people solely blame carbs. It's processed carbs and sugar, hyper-palatable foods, lack of sleep, lack of sun exposure, microbiome damage from antibiotics, and a ton of other lifestyle factors. But once you're in a compromised state (autoimmune, type 2 diabetes, hypertension, etc.), the ketogenic diet…

Apparently Inuit people are actually fine on carbs because the meat they eat tends to retain its glycogen stores better because of the arctic conditions.

Inuits have mutated to adapt to that diet.

https://www.ucl.ac.uk/news/2015/sep/how-inuit-adapted-ice-ag...

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#26
post #2

> This may suggest that our lineage has evolved specific adaptations to digest starch-rich foods, underlining the long and continuing importance of these staples in our diet This reminds me of the interest in keto dieting and the frustrating misunderstanding that carbs are the cause of excess weight, diabetes etc. If that were true, the whole world would be diabetic and obese, since everywhere has a staple carb. It's…

Until recently, everyone has lived near the border of starvation, and not had an opportunity to get obese.

Since the agricultural revolution, carbs are what we have been able to mass produce, and therefore breed ourselves to greater numbers on. That it probably hasn't been the ideal diet for us is a distant secondary concern.

Now that we're finally overproducing food, we actually are getting obese on the carb diet. Coincidence? Maybe.

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#27
post #2

> This may suggest that our lineage has evolved specific adaptations to digest starch-rich foods, underlining the long and continuing importance of these staples in our diet This reminds me of the interest in keto dieting and the frustrating misunderstanding that carbs are the cause of excess weight, diabetes etc. If that were true, the whole world would be diabetic and obese, since everywhere has a staple carb. It's…

Until recently, everyone has lived near the border of starvation, and not had an opportunity to get obese. Since the agricultural revolution, carbs are what we have been able to mass produce, and therefore breed ourselves to greater numbers on. That it probably hasn't been the ideal diet for us is a distant secondary concern. Now that we're finally overproducing food, we actually are getting obese on the carb diet. C…

I think the Venus of Willendorf and her equally thicc cousins are, if you'll excuse the expression, ample proof that some people had an opportunity to get obese long before the agricultural revolution.

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#28
post #2

> This may suggest that our lineage has evolved specific adaptations to digest starch-rich foods, underlining the long and continuing importance of these staples in our diet This reminds me of the interest in keto dieting and the frustrating misunderstanding that carbs are the cause of excess weight, diabetes etc. If that were true, the whole world would be diabetic and obese, since everywhere has a staple carb. It's…

Until recently, everyone has lived near the border of starvation, and not had an opportunity to get obese. Since the agricultural revolution, carbs are what we have been able to mass produce, and therefore breed ourselves to greater numbers on. That it probably hasn't been the ideal diet for us is a distant secondary concern. Now that we're finally overproducing food, we actually are getting obese on the carb diet. C…

I believe that you're missing the point. We aren't getting obese on the carb diet. We are getting obese from excess calories and dietary fat. De novo lipogenesis (producing fat from only carbs) is inefficient and uncommon. Storing carbs as body fat via de novo lipogenesis is inefficient; storing dietary fat in body fat reserves is easy and efficient.

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#29
post #20

Earlier quoted context omitted.

The "we" in the sentence is homo sapiens. Neanderthals and Denisovans were not the same species as us. > "Unlike Neanderthals and Denisovans, who had only two diploid copies, [homo sapiens] carry up to 20 copies of the AMY1 gene, which produces salivary amylase. "

Doesn't that mean we've evolved to eat a lot of starch so the more natural thing for humans to eat is therefore starch, if you follow this line of reasoning? And therefore, we've "evolved beyond" the keto diet? FWIW, I do not think this is good reasoning.

[deleted]

Re: Animals living alongside humans produce amylase, enzyme that breaks down starch

#30
post #20

Earlier quoted context omitted.

The "we" in the sentence is homo sapiens. Neanderthals and Denisovans were not the same species as us. > "Unlike Neanderthals and Denisovans, who had only two diploid copies, [homo sapiens] carry up to 20 copies of the AMY1 gene, which produces salivary amylase. "

Doesn't that mean we've evolved to eat a lot of starch so the more natural thing for humans to eat is therefore starch, if you follow this line of reasoning? And therefore, we've "evolved beyond" the keto diet? FWIW, I do not think this is good reasoning.

OP is not making a claim here, he is pointing out counter evidence to someone else's claim, which is that keto diets are optimal for homo sapiens because that is what our genetic ancestors evolved to eat. The presence of significantly more genes for amylase provides strong (although far from conclusive) evidence that homo sapiens have evolved to eat a much more varied diet than paleo proponents assert.
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