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Cannabidiol in Anxiety and Sleep: A Large Case Series

ncbi.nlm.nih.gov

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Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#51

Post by gnulinux »

TaylorAlexander wrote: post #46
duncan-donuts wrote: post #39

Earlier quoted context omitted.

This is the most exciting thing about legalization to me. If I could go buy high cbd strains with a manageable level of thc I’d be first in line. I don’t want to get super high on thc. I just want all of the other effects.

They definitely sell 10:1 CBD:THC and 100% CBD in California. 100% CBD weed doesn’t even need to be sold at dispensaries. They sell that at lots of stores. My mom said the feed store has CBD oil for your pets. Legalization is the best.

CBD is "technically" federally legal since the 2018 Farm Bill. Practically, it's in this limbo position where if it's allowed without any restrictions it's very hard to control THC which is a Sched 1 drug that Feds care a lot about. That's why even though you can buy CBD from your closest market, people still get busted for "smuggling" because CBD cannabis (and hemp) looks identical to marijuana. So currently it's in this weird limbo state where it's 100% legal but its legality cannot be enforced so in some places it's not possible to find CBD.

Also, I think CBD is effective for dogs and cats (e.g. for seizures) but apparently there is some evidence THC is toxic to cats and dogs. So PLEASE be sure your CBD doesn't include THC before feeding it to your pet.

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#52

Post by grenoire »

mettamage wrote: post #19
spectramax wrote: post #6

Stupid question but I’ve always wondered this - I hear Cannabis is used for anxiety relief but doesn’t smoking marijuana induce anxiety? Everyone I know who has smoked weed agrees with my experience - they’ve encountered some level of anxiety and paranoia. So, how exactly does weed help in reducing anxiety? Edit: Follow up question -> Is weed used to treat anxiety during the high or when you are normal (and have gene…

To summarize a bit unnuanced: THC induces paranoia CBD reduces it The ratio is an important one between them as it alters the experience a lot. Weed is a bit like love, the term is convoluted and overloaded. E.g. Dutch weed: HIGH in THC! Normal in CBD. Oh dear, the Dutchies... Sigh Swiss weed: high in CBD, extremely low in THC The experience? Completely different. Sources (cannot Google search atm, am on mobile): - I…

More or less my experience as well, stuff I go for regularly are 13-15% THC to 1% CBD. Depending on where you get your weed from, coffeeshops do occasionally mark their ratios.

I should probably go for higher CBD ones...

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#53

Post by inciampati »

gnulinux wrote: post #50
colordrops wrote: post #22

Earlier quoted context omitted.

As others have mentioned, it's the THC component that can cause anxiety. I have high anxiety and THC usually makes it worse, but that's just temporary. I find that THC is bringing subconscious worries and pains to the surface, and if I actively process them, then I come out of the high feeling extreme relaxation and peace, more than I ever got from pure CBD.

Just a data point. I dealt with anxiety my entire life, and too much weed absolutely destroys me but small amount of weed definitely calms me down. When I smoke too much weed, it really doesn't feel like my anxieties deep down are surfaces. It feels like my brain is making up new stupid things. To me, weed is a very strong sensory experience. When I'm too high it almost feels I'm hearing too much, feeling too much, s…

What kind of made up anxiety have you encountered? I ask just to understand. I've never run into an anxiety after smoking weed that wasn't rooted in reality. I find it helpful for the same reasons the previous poster stated.

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#54

Post by enz »

> The final sample consisted of 72 adults presenting with primary concerns of anxiety (n = 47) or poor sleep (n = 25).

72 adults seems a bit low to me. Does anyone knows if it's indeed low or a pretty normal sample for that kind of study?

Besides, this study does not seem placebo-proof, right?

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#55

Post by mmanfrin »

colordrops wrote: post #22
spectramax wrote: post #6

Stupid question but I’ve always wondered this - I hear Cannabis is used for anxiety relief but doesn’t smoking marijuana induce anxiety? Everyone I know who has smoked weed agrees with my experience - they’ve encountered some level of anxiety and paranoia. So, how exactly does weed help in reducing anxiety? Edit: Follow up question -> Is weed used to treat anxiety during the high or when you are normal (and have gene…

As others have mentioned, it's the THC component that can cause anxiety. I have high anxiety and THC usually makes it worse, but that's just temporary. I find that THC is bringing subconscious worries and pains to the surface, and if I actively process them, then I come out of the high feeling extreme relaxation and peace, more than I ever got from pure CBD.

This is a good way of putting it.

I view THC as having an 'echoing' effect of whatever I am feeling. If something makes me laugh, the feeling of laughing will cause more laughter. If I am feeling anxiety, the feeling of anxiety will cause more anxiety.

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#56

Post by bfuller »

gnulinux wrote: post #51
TaylorAlexander wrote: post #46

Earlier quoted context omitted.

They definitely sell 10:1 CBD:THC and 100% CBD in California. 100% CBD weed doesn’t even need to be sold at dispensaries. They sell that at lots of stores. My mom said the feed store has CBD oil for your pets. Legalization is the best.

CBD is "technically" federally legal since the 2018 Farm Bill. Practically, it's in this limbo position where if it's allowed without any restrictions it's very hard to control THC which is a Sched 1 drug that Feds care a lot about. That's why even though you can buy CBD from your closest market, people still get busted for "smuggling" because CBD cannabis (and hemp) looks identical to marijuana. So currently it's in…

yes, its technically federally legal, but some cities around me are still prosecuting CBD possession

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#57

Post by nikkwong »

jaequery wrote: post #41
mettamage wrote: post #3

Why I post this: I am trying to sleep but can’t (on my phone to not wake anyone). I was wondering whether CBD might help. The study is simply a discussion prompt. My query also found [1]. I wonder who else has some insight into CBD. Edit: since this comment is quite down the discussion thread I would like to promote another topic [2]. It is about creating wearables that are able to measure stress. Measuring stress [2…

I’ve had chronic insomnia for over 3 years. The day I started CBD, was about 4 months ago. Right before that, my option was to try Ambien that I had to pry off from the doctors hands. I’ve not had the guts to try it after hearing it messes with your brain and causes you to have suicidal thoughts. So I tried CBD after a quick research. First night, I didn’t feel a difference. I did feel a bit sleepier but I thought th…

Where have you read that CBD increases the amount of deep sleep? I have looked into this quite extensively, and never found any information that suggested that.

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#58

Post by hn_throwaway_99 »

enz wrote: post #54

> The final sample consisted of 72 adults presenting with primary concerns of anxiety (n = 47) or poor sleep (n = 25). 72 adults seems a bit low to me. Does anyone knows if it's indeed low or a pretty normal sample for that kind of study? Besides, this study does not seem placebo-proof, right?

It's not a study. It's a post-facto case series, meaning they looked at some users who were given CBD and see how they responded. There was no control group.

In other words, certainly raises interest to do an actual study, but absolutely 0 other conclusions can be drawn from this report.

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#59

Post by hn_throwaway_99 »

whalesalad wrote: post #36
hn_throwaway_99 wrote: post #23

Earlier quoted context omitted.

In my experience, if I smoke a very small amount of weed (like literally one hit) it can relax me and make me less anxious. It slows things down, and can just generally numb some of my underlying anxieties. However, it doesn't take much for me to cross that threshold where it can make me extremely paranoid. Usually this is what I call the "will I be stuck this way forever" threshold, where I get stoned to the point w…

The less you use, the more your body will become sensitive to the smaller amounts of it. Meaning, if you dose correctly, you can actually use less to achieve more. So yep, dosage is extremely critical with THC.

> The less you use, the more your body will become sensitive to the smaller amounts of it.

Do you have any reference to back that up? I ask because I am genuinely curious. I haven't heard this before, and usually with most other drugs the opposite happens, i.e. you slowly build a tolerance that requires taking higher does to acheive the same effects.

Re: Cannabidiol in Anxiety and Sleep: A Large Case Series

#60

Post by nydel »

jey wrote: post #2

This is a case series and literally has no control group. What's the background rate of people getting better without using CBD?

A large case series[1] on reviewing dubious publications on Cannabidiol indicates substantial increase in anxiety among critical thinkers. A causative correlation[2] is concluded by the series.

[1] https://news.ycombinator.com/item?id=20340937

[2] https://www.xceleratemaths.com/algebra/images/graph-y=x.gif

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