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Magnesium and major depression (2011)

ncbi.nlm.nih.gov

181–190 of 235 posts

Re: Magnesium and major depression (2011)

#181

I'm quite skeptical on supplements, but I have to say that Magnesium helps me sleep like a baby and feel much more relaxed generally.

For the last couple of months I've been taking a 500mg magnesium and a .30 mg melatonin 10 minutes before I get into bed. Some nights I feel like I don't even roll over, I just wake up the next morning feeling like I've had really deep and uninterrupted sleep.

Re: Magnesium and major depression (2011)

#182
post #151
post #148

Earlier quoted context omitted.

> Did you test your magnesium level by blood tests? No, hair tests. Which I dread talking about in forums like this as it can be a red cloth to motivated skeptics/cynics (of which I used to be one until I was blessed with the opportunity to endure this experience), but the results have been consistent with my experienced-symptoms over a long period of time (10 years so far), and the correlation with my emotional work…

I mean the fact that it works as a treatment. We don't have much more than doing a blind test and checking improvement to test causality. There are so many real world factors that elimination wouldn't work. I see that you like Jung so I'm sure you're aware that there's more than neurochemistry that can influence it, but when talking about drugs, incentives seem to be aligned such that one should expect patented subst…

Right yeah, I see those mentions of past studies, which suggest some positive results but don’t say much about long-term outcomes. (My own experience has been that in early stages of feeling impaired, supplementation of Mg and other nutrients would bring about short-term mood benefits but subside in the medium to long-term (and show no measured changes in hair tests), even with consistent ongoing supplementation, suggesting that the emotional/life issues are an overriding factor long-term.

I don't doubt that a simple dietary deficiency of Mg may be a causal factor for some, perhaps even most people. But studies like these often seem happy to report positive outcomes after finding, say, 70% short-term efficacy, but ignore the remainder, in which the causation may be very different.

> incentives seem to be aligned such that one should expect patented substances to have the most papers showing positive results vs something cheap and readily available.

Yes, which has been a source of frustration, but I understand modern economics, so I get it.

> Plus I thought you were only basing this N=1 on blood tests so I didn't like dismissal of paper based on that, thus the tone of my prev reply, I'm sorry about that.

Cheers for that.

Re: Magnesium and major depression (2011)

#184
post #174

Earlier quoted context omitted.

I would add at least two more that I think are huge and largely overlooked most of the time: a. Loss of a sense of community and the very real practical support that provides with moving from small town/rural to big city life for most people. b. "Sick building syndrome" which I think is far, far more widespread than is generally recognized. Among other things, indoor air quality is crap more often than not.

I agree and think these actually enormously overshadow all of the previously mentioned factors except maybe diet. We weren't meant to live out our lives in seas of isolated little poorly ventilated boxes.

Sleeping in a tent for nearly six years actually did my health a world of good. It also dramatically changed my perspective on the state of housing in modern America and its relationship to myriad problems, including health issues, in ways that aren't likely to be taken seriously by most people any time soon.

When I comment on such things, it typically gets downvotes and/or snarky, dismissive replies and personal attacks.

Re: Magnesium and major depression (2011)

#185
post #11

I have found that taking Magnesium is like turning a switch on in my head and I'm suddenly happy again. I don't get upset or angry in the same way, I'm more patient and my thoughts are not obsessive. Magnesium is best taken with calcium and vitamin D as both are used in the uptake of magnesium. I have found that processed foods, alcohol, caffeine and sugar all make me worse, but magnesium gives me the will power to c…

> magnesium

Yes! Magnesium changed my life!

I was certain that I was living with depression... until I read somewhere that lactose intolerance can lead to magnesium deficiency.

I started taking Magnesium and felt the effect immediately. All of my body is physically relaxed. I struggled with muscle cramps and spasms, they are gone thanks to increasing my magnesium intake. It's as if my muscles being under stress created anxiety and that anxiety reduced my ability to be happy.

I have also learned that I need to supplement with vitamin D during the winter to avoid having SAD. Vitamin D + Magnesium are also my solution to happiness.

Re: Magnesium and major depression (2011)

#186
post #11

I have found that taking Magnesium is like turning a switch on in my head and I'm suddenly happy again. I don't get upset or angry in the same way, I'm more patient and my thoughts are not obsessive. Magnesium is best taken with calcium and vitamin D as both are used in the uptake of magnesium. I have found that processed foods, alcohol, caffeine and sugar all make me worse, but magnesium gives me the will power to c…

I started taking magnesium on advice of a chiropractor, as I was getting a painful calcium deposit. I take a magnesium/calcium deposit, and later added vitamin D.

I don't know if it's the root cause, but my mental outlook has improved over the past few years.

Re: Magnesium and major depression (2011)

#187

Earlier quoted context omitted.

There have been a number of experiments where they gave patients more magnesium, and in response most patients reduce their depression by a statistically significant amount. The inverse was found when they gave them calcium (more calcium increases depression). It's all about the ratio of calcium to magnesium. We're a society that consistently gets way too much calcium and way too little magnesium. That's because our…

> There have been a number of experiments where they gave patients more magnesium, and in response most patients reduce their depression by a statistically significant amount Can you link to those studies please? > more calcium increases depression now that really is curious. Again, do you have a link? TIA

please check edit.

Re: Magnesium and major depression (2011)

#188
post #165

Earlier quoted context omitted.

You should do some learning on your own and not just read what I post https://extension.psu.edu/industrial-hemp-production

> You should do some learning on your own and not just read what I post > https://extension.psu.edu/industrial-hemp-production 1. You should read the links that you post. 2. You should post links that contain evidence for your claims, instead of links that don't. I'm sorry to be glib here, but surely you can see the problem with telling ME to go find evidence for YOUR claims, when you can't even be bothered to find e…

:)

So you have read enough to see but you need some sort of proof aside from the fact humans have been using it as feed for as long as history has been recorded ?

https://www.feedipedia.org/node/50

Given the fact humans didnt even know they had the endocannabanoid system until the 90's I am not surprised there isnt technical evidence showing the correlation.

Common sense should prevail here, but you are correct... even though the cannabanoid receptors are one of the most populous receptors in the brain and folks using CBD oil have been reporting all sorts of interesting reactions to it ( I personally can tell you it relieves pain from nerve damage ). Nothing in the links I posted directly correlates anything.

Odd how the money in the cotton industry lobbied and killed the hemp industry isnt it?

Trivia ... US Constitution is written on Hemp Paper

Re: Magnesium and major depression (2011)

#189

The onset of depression has greatly increased in incidence, and it is affecting people much earlier in their lives during the late 20th century and early 21st century than before the 20th century (Meyer and Quenzar, 2005). The reasons for these findings are not quite clear, but inadequate dietary Mg is prevalent in America and is the most likely cause. There is probably a real increase in depression, coupled with a c…

Read the entire article. It also talks about the increased Mg excretion effect of stress hormones.

It’s a combination of lower intake of what already is a micronutrient, increased excretion (consequence of the lifestyle changes), and hard to diagnose (because serum Mg levels stay stable, only cellular Mg reserves are depleted).

I had a couple neurological issues in the past and had a good endocrinologist suggest me Mg (quelated) and he explained all that is mentioned on the article.

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