Live data from Hacker News

Magnesium and major depression (2011)

ncbi.nlm.nih.gov

41–50 of 235 posts

Re: Magnesium and major depression (2011)

#42
post #15

Earlier quoted context omitted.

>lithium [...] was discovered by accident. No it was not. Development of treatment with lithium was very much a part of psychiatric normal science.

I'm sorry - you are wrong. John Cade found the effects - with animals - by accident. And he was widely ignored because of his lack of fundamental, industry-wide standards for exploration. Neverless: lithium is now the way to go with clinical treatment of a wide range of disorders and reducing self-harm and suicide rates. The problem so far: nobody is sure why it works. The dose is worth mentioning. Clients receive a…

Wish we knew why it works. But it's also nice that something is accepted based on data alone. Many people in science tend to reject claims based on a lack of explanation alone. But that's the whole point - observe and then try to figure out why or how.

Re: Magnesium and major depression (2011)

#43
I'm a cardio addict and do 250mg liquid Citrate and 200mg of Bisglycinate before sleep. Otherwise restless legs syndrome would kick in badly during the night. Sometimes adding 1.000mg of Gaba also helps with recovery and falling asleep.

Just make sure to stay away from cheap Mg Oxide since bio-availability is somewhere in the 4% range and usually comes in Multi-anything pills.

Re: Magnesium and major depression (2011)

#44
>Magnesium has been largely removed from processed foods, especially refined grains, in the Western world, harming the brain and causing mood disorders.

This seems to be the case with many such nutrients.

I almost wonder if the most effective solution isn't a medical approach but a medically-informed, government-led incentive program to convince food manufacturers to reintroduce the essential nutrients they strip out of food.

Re: Magnesium and major depression (2011)

#45
post #15

Earlier quoted context omitted.

>lithium [...] was discovered by accident. No it was not. Development of treatment with lithium was very much a part of psychiatric normal science.

I'm sorry - you are wrong. John Cade found the effects - with animals - by accident. And he was widely ignored because of his lack of fundamental, industry-wide standards for exploration. Neverless: lithium is now the way to go with clinical treatment of a wide range of disorders and reducing self-harm and suicide rates. The problem so far: nobody is sure why it works. The dose is worth mentioning. Clients receive a…

Psychiatrists say the difference between a dose where you start to see some effect, and the toxic dose, is often only 1:2. So experimenting with lithium is hazardous and needs careful, almost, titration.

Re: Magnesium and major depression (2011)

#46
post #20

I'm quite skeptical on supplements, but I have to say that Magnesium helps me sleep like a baby and feel much more relaxed generally.

I recently realised that Mg is a reliable way for me to stop teeth grinding in my sleep.

I am interested in hearing more. Did you try Mg with the intent of grinding your teeth less?

Re: Magnesium and major depression (2011)

#47

I take magnesium in the form of trace mineral drops. These are de-salted sea water deposits. Besides magnesium they contain other rare trace minerals which would otherwise be difficult to obtain, particularly lithium which has quite strong evidence of mellowing mood. The liquid form leads me to believe they absorb well but not sure if that's actually true. Edit to say I believe these drops have reduced my anxiety and…

Where do you find such things?

https://www.amazon.com/Trace-Minerals-Research-Concentrace-M...

Re: Magnesium and major depression (2011)

#48

I take magnesium in the form of trace mineral drops. These are de-salted sea water deposits. Besides magnesium they contain other rare trace minerals which would otherwise be difficult to obtain, particularly lithium which has quite strong evidence of mellowing mood. The liquid form leads me to believe they absorb well but not sure if that's actually true. Edit to say I believe these drops have reduced my anxiety and…

Does the body effectively absorb trace amounts of minerals?

Edit. I'm not implying any homeopathy antics, am genuinely curious.

Re: Magnesium and major depression (2011)

#49
I can't speak for depression, but I was suffering from muscle spasms and tremors last year (both external and internal). Magnesium was suggested, I now take two a day and they have almost entirely dissipated. It certainly wouldn't surprise me that the presence or lack of such substances could have significant effects upon the brain too though I have noticed no changes in that regard.

Re: Magnesium and major depression (2011)

#50
post #11

I have found that taking Magnesium is like turning a switch on in my head and I'm suddenly happy again. I don't get upset or angry in the same way, I'm more patient and my thoughts are not obsessive. Magnesium is best taken with calcium and vitamin D as both are used in the uptake of magnesium. I have found that processed foods, alcohol, caffeine and sugar all make me worse, but magnesium gives me the will power to c…

What form are you taking them?

Glycinate is ~most used/benefit/cost I think (i do).

There's also threonate which is in a weird state with effects,withdrawals,price etc. I have some and still haven't tried it.

Post reply on HN