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How does the body figure out which side is left and which side is right? I can think of an easy way to break symmetry but it seems harder to consistently know which side is which.
The only explanation I can think of as to why this would cause an issue is that not everything is mirrored.
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What's really whack when you consider it is the same neuromuscular system that allows us to walk can also be repurposed to drive a car, fly a plane and operate other machinery. Isn’t this because we purposely design all those things around our anatomy though? I’d imagine alien octopuses’ vehicles would be designed around their anatomy and they would have no trouble using them.
Not OP, but I always thought it’s amazing how it becomes second nature. You think you want to turn left and slow down, not I have to use my left foot to slowly press the brake and slowly move my hands in a circle while grasping.
How does the body figure out which side is left and which side is right? I can think of an easy way to break symmetry but it seems harder to consistently know which side is which.
Short answer: at the single cell stage there's a cilium that, spins in a single direction and establishes chirality. People with immotile cilia thus have a 50/50 chance of getting SI, because the developing body chooses randomly.
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I also have Situs Inversus Totalis. Thankfully I haven't had any major health incidents to date, and my experiences with doctors and nurses has been similar. EKGs in particular can be quite interesting. :) I'm also diagnosed with Primary Ciliary Dyskinesia, and your mention of asthma issues as a child had me wondering if it's something you're aware of? About 50% of people with PCD also have Situs Inversus Totalis. Th…
Holy shit! Yeah perhaps, I'm due for a medical examination, I'll bring this up. Do you often get chest infections too? Apparently that's very common as it is with me and those who have DC or Situs Inversus.
Earlier quoted context omitted.
Not OP, but I always thought it’s amazing how it becomes second nature. You think you want to turn left and slow down, not I have to use my left foot to slowly press the brake and slowly move my hands in a circle while grasping.
Breaking with the left foot sounds really dangerous. What is the right foot doing? ...though I guess you were just reinforcing your point: driving becomes so second nature that you forget the implementation details.
Wasn’t that the premise of Deep Throat?
Why does a prefect mirror image of organs in your body result in things not working? One would assume most things would work... The only explanation I can think of as to why this would cause an issue is that not everything is mirrored.
In the absence of congenital heart defects, individuals with situs inversus are phenotypically normal, and can live normal healthy lives, without any complications related to their medical condition. There is a 5–10% prevalence of congenital heart disease in individuals with situs inversus totalis
The article states that situs inversus sufferers "invariably" have severe heart defects, and generally gives a pretty bleak outlook for the condition. And yet this woman made it to 99, without diagnosis, despite several surgeries. I wonder if anyone has done a statistical analysis to find the true number of undiagnosed cases, because it would seem to be very high.
They explain the likely reason: > But Bentley was an anomaly, one of the few born with the condition that didn't have heart defects, Walker said. "That is almost certainly the factor that contributed most to her long life," he said.
I'm also not keen on their use of the word 'survivor' in the same paragraph.
Why does a prefect mirror image of organs in your body result in things not working? One would assume most things would work... The only explanation I can think of as to why this would cause an issue is that not everything is mirrored.
In many cases, it doesn't cause problems. In the absence of congenital heart defects, individuals with situs inversus are phenotypically normal, and can live normal healthy lives, without any complications related to their medical condition. There is a 5–10% prevalence of congenital heart disease in individuals with situs inversus totalis https://en.m.wikipedia.org/wiki/Situs_inversus
I only ask because it wasn't explained on wikipedia.