61–70 of 108 posts
Does this mean that inflammation of the brain is to be ruled out as a cause?
Is it possible that these prions were also acquired by human through meat consumption? As in the case with PrP prion from Mad Cow Disease which spread through meat eating as well. Another very similar case is by eating fruit bats containing toxic BMAA, which has a very similar structure to L-Serine amino acid causing it to be picked up instead during the protein synthesis process and resulting in a misfolded version.…
"Few studies have looked carefully at the risk of dementia in vegetarians versus other people, and the data is contradictory. One small study of California residents found that meat eaters were more likely to become demented than their vegetarian counterparts. Another study in Alzheimer’s patients, however, found that adhering to a strict vegetarian diet resulted in lower cognition compared to a pescatarian diet (i.e., a diet that includes fish)."
https://www.alzdiscovery.org/cognitive-vitality/blog/vegetar...
Earlier quoted context omitted.
Speculatively, in the future we may be able to design proteins that would target the prions and destroy them or refold them into less harmful shapes. To do that we would need to 1. know what protein shape would be required and 2. be able to figure out how to make that shape (what sequence would happen to fold itself into that shape). I would think we would need to advance quite a bit more in protein science before th…
Just to provide background, what you describe is nowhere close to feasible. Designing novel proteins is computationally intractable. It took evolution billions of years and parallel optimization to figure out how to problem solve with polypeptides. We're not even at the punch card phase.
Earlier quoted context omitted.
that's an argument from authority rather than one of science though. we believe things only once we've exhausted our attempts to disprove it
> that's an argument from authority rather than one of science though. No. An appeal to authority would be "this must be true because someone authoritative said it". Saying "I am willing to treat this claim more credibly than other claims because the source is credible" is not a logical fallacy.
That's a personal heuristic - a very reasonable one, but it's still an argument from authority.
Is it possible that these prions were also acquired by human through meat consumption? As in the case with PrP prion from Mad Cow Disease which spread through meat eating as well. Another very similar case is by eating fruit bats containing toxic BMAA, which has a very similar structure to L-Serine amino acid causing it to be picked up instead during the protein synthesis process and resulting in a misfolded version.…
Interesting topic. Here is an anecdote that I found through a simple web search that somewhat addresses your question: "Few studies have looked carefully at the risk of dementia in vegetarians versus other people, and the data is contradictory. One small study of California residents found that meat eaters were more likely to become demented than their vegetarian counterparts. Another study in Alzheimer’s patients, h…
Our DNA contains the sequence of folding steps instruction for each protein to fold. So for a protein to misfold itself, could this mean it must have received an incorrect instruction from the source? As we know, damages to DNA are often a result of foreign agents or coming from external environmental factors. Prevention is always better than a cure so it is probably a lot easier to figure out the source and eliminate that rather than trying to change the structure of these molecules which is extremely difficult.
A cute dog is dancing in video Just watch this video and try to control your laugh http://bit.ly/2ZK1XVs
See how a Turkey saved the life of his friends Even those birds also have love in their hearts http://bit.ly/2WhAiZS
Guy made world record He drive car on two wheels See his video how he is driving http://bit.ly/2ZOYaWX
See the video of this man he is catching balls and he is wearing blindfold http://bit.ly/2Vx4Mdl .
Y'all, please never post university press releases about single scientific studies . They are the worst thing. Every major human problem has been declared solved by one of them. They are even worse than posting single scientific study papers themselves at the time of publication, and that's still pretty bad, because of the overwhelming incentive to create exciting studies that are wrong, and our current inability to…
Y'all, please never post university press releases about single scientific studies . They are the worst thing. Every major human problem has been declared solved by one of them. They are even worse than posting single scientific study papers themselves at the time of publication, and that's still pretty bad, because of the overwhelming incentive to create exciting studies that are wrong, and our current inability to…
Instant throwback to 1997's Redneck Rampage game about US hillbillys..
Pretty awesome work. Looks like we don’t have obvious ways to avoid these classes of proteins in the same way we can just avoid tainted meat and abstain from cannibalism... https://en.wikipedia.org/wiki/Amyloid https://en.wikipedia.org/wiki/Tau_protein
Or do we? People taking acyclovir regularly (to suppress HSV1 and 2 symptoms) have been found to have a 10 fold decrease in risk of getting Alzheimer's (Taiwanese study). https://www.medicalnewstoday.com/articles/322463.php Additional studies are currently ongoing to confirm this in the US. The scientific "journalists" seem to jump to the conclusion that therefor HSV1,2 must be cuasal for Alzheimer's. But it could be…
Y'all, please never post university press releases about single scientific studies . They are the worst thing. Every major human problem has been declared solved by one of them. They are even worse than posting single scientific study papers themselves at the time of publication, and that's still pretty bad, because of the overwhelming incentive to create exciting studies that are wrong, and our current inability to…