It would not hurt to ask about current and future dilution and how exactly the company is currently estimating share value. Getting a straight answer is likely going to be a challenge though.
Assuming the company in question is not "public" then yes it would be good to be conservative about the valuation of their stock. It would be safe to assume that any number of shares of stock (options or grants) are worthless.
From my personal experience, you will likely be disappointed in whatever is left after investors and principles take their cut. They are almost certainly going to be privileged in a buyout over the holders of "common" stock. I have been in acquisitions where my option price was more than the value of my shares. I don't think this is uncommon.
Sorry, I see you also asked what "Stock Options" and "Stock Grants" are. Grants are like a flat out gift. The company gifts you some number of shares. Options give you the opportunity to purchase shares for a set prices regardless of what the current value of the shares actually is. Options are great if the option price is less than the actual price. They are worthless if it is the other way around.
Again, remember that "investors" and "principles" will almost certainly be compensated first out of the pot of money from an acquisition. After that, whatever is left (usually little to none) will determine the actual share price. However with a "big exit" what is left might make you rich :-) Just don't bet on it.