Live data from Hacker News

Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

mdedge.com

71–80 of 122 posts

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#71

Earlier quoted context omitted.

3. Approaching hot girls.

just wear a liquid cooling vest

Or just go back to the 90s and tell yourself that, no matter how cool Hypercolor shirts are in advertisements, they won't actually make YOU cool, and nobody needs a garment that draws additional attention to their sweaty armpits.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#72
I was temporally prescribed metoprolol for some palpitations but also discovered it does helps with anxiety symptoms, so I still use it sometimes. At first it gave me nightmares but they stopped. I wanted to try propranolol (probably better) but I read the side effects are worse than those of metoprolol so I didn’t.

Edit: I read the side effects are basically the same, including ED.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#73

> Fifteen received 40 mg of propranolol after spending 2 minutes in proximity to a large tarantula, 15 got placebo, and another 15 received propranolol without exposure to a tarantula. What about a group who was exposed to the tarantula without the propranolol?

The 15 that got placebo didn’t get propranolol

But it's not clear if they were exposed to the tarantula.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#74

I was temporally prescribed metoprolol for some palpitations but also discovered it does helps with anxiety symptoms, so I still use it sometimes. At first it gave me nightmares but they stopped. I wanted to try propranolol (probably better) but I read the side effects are worse than those of metoprolol so I didn’t. Edit: I read the side effects are basically the same, including ED.

As described at the link above, it would be inappropriate/harmful for a physician to prescribe more than a single dose of propranolol for this purpose — to be taken in concert with a therapeutic session and likely never again — but absolutely not as a take-home prescription of more than a single pill. This is the same type of prescribing regimen that we’re finding out psilocybin works with too, and you wouldn’t get a take-home supply of that either.

That you can acquire the drug readily for other medical reasons is not in any way a reason to start self-prescribing it for anxiety. Without the trauma-inducing psych session, the anti-PTSD benefit they describe has no chance to occur. And it’s a bad plan to give yourself traumatic recall flashbacks - a bad trip by any definition - without some sort of competent mental support from competent human beings.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#76

Living with someone with crippling PTSD and anxiety disorders, I'm thrilled to hear about this study. As someone who's dealt with an oppressive government (which is where the PTSD and anxiety came from), I wonder if this therapy can be weaponized by the powerful to oppress the powerless. The rise of the warrior cop is bad enough, but what about a crack squad that has been chemically desensitized to killing in cold bl…

That worry feels like a stretch, because right now, the many oppressive governments of the world are not in the least suffering logistical difficulties due to their stormtroopers getting PTSD. There are I think 2 main reasons why not: - Stormtroopers are people who have non functioning empathy, by nature or nurture, they don't experience killing in cold blood as horrific. - Stormtroopers are a cheap commodity. The op…

A Black Mirror episode considers a flip side of that coin: the threat of PTSD as a blackmail device. Granted, alongside some other far-fetched circumstances.

https://en.m.wikipedia.org/wiki/Men_Against_Fire

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#78

Living with someone with crippling PTSD and anxiety disorders, I'm thrilled to hear about this study. As someone who's dealt with an oppressive government (which is where the PTSD and anxiety came from), I wonder if this therapy can be weaponized by the powerful to oppress the powerless. The rise of the warrior cop is bad enough, but what about a crack squad that has been chemically desensitized to killing in cold bl…

> The rise of the warrior cop is bad enough, but what about a crack squad that has been chemically desensitized to killing in cold blood, taking orders from corrupt officials?

I read Eichmann in Jerusalem recently. One of the main arguments of the book is that people don't need to be extraordinary (i.e. lacking a conscience or particularly fanatical) in order to do terrible things.

The book is controversial but I think that argument is correct. The problem with Nazi Germany was not a generation of Germans who happened to be born without consciences. And, horrifyingly, we've seen this pattern repeat across time and space. It just isn't necessary to chemically alter people to get them to perform actions that we would describe as evil.

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#79

This is also pictured in NOVA: memory hackers on Netflix (last accessed in Brazil, in case it is region locked). It documents the process of treating arachnophobia in a patient that clearly has an extreme aversion to spiders and it is incredible.

Stupid question: can you watch it if you have arachnophobia yourself?

Re: Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders

#80
post #35

I have been taking low dosage Propranolol for about a year now. It was prescribed for me for my hemiplegic migraines. Combined with exercise and occasional CBD oil it has completely eliminated migraines from my life. This medication is absolutely brilliant and harmless. Also keeps my resting heart rate around 55. If you struggle with migraines, talk to your neurologist, for me it was a life changer.

My resting heart rate is about 55, and I don't do a lot (arguably not any) of cardio. I'm probably in the group of people who shouldn't take propranolol.

my resting heart rate was high 30s-low 40s. I was put on propranolol and now my resting heart rate is in the mid 40s. I am the exact opposite of an athlete.
Post reply on HN